Myristoylated Alanine-Rich C Kinase Substrate
"Myristoylated Alanine-Rich C Kinase Substrate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.
| Descriptor ID |
D000076250
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| MeSH Number(s) |
D05.750.078.730.556 D12.644.360.537 D12.776.157.142.375 D12.776.157.687.496 D12.776.220.525.556 D12.776.476.539 D12.776.543.637 D12.776.660.720.496
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myristoylated Alanine-Rich C Kinase Substrate".
Below are MeSH descriptors whose meaning is more specific than "Myristoylated Alanine-Rich C Kinase Substrate".
This graph shows the total number of publications written about "Myristoylated Alanine-Rich C Kinase Substrate" by people in this website by year, and whether "Myristoylated Alanine-Rich C Kinase Substrate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myristoylated Alanine-Rich C Kinase Substrate" by people in Profiles.
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CLL cells are moved by the MARCKS brothers. Blood. 2021 08 19; 138(7):503-504.
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Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors. Oncotarget. 2016 Nov 15; 7(46):74779-74796.
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Essential role of MARCKS in cortical actin dynamics during gastrulation movements. J Cell Biol. 2004 Jan 19; 164(2):169-74.
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Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10587-92.