AMP-Activated Protein Kinases
"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.
| Descriptor ID |
D055372
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
|
| Concept/Terms |
AMP-Activated Protein Kinases- AMP-Activated Protein Kinases
- AMP Activated Protein Kinases
- AMP-Activated Kinase
- AMP Activated Kinase
- AMP-Activated Protein Kinase
- AMP Activated Protein Kinase
- 5'-AMP-Activated Protein Kinase
- 5' AMP Activated Protein Kinase
AMP-Activated Protein Kinase alpha Subunits- AMP-Activated Protein Kinase alpha Subunits
- AMP Activated Protein Kinase alpha Subunits
- PRKAA
- AMP-Activated Protein Kinase alpha Subunit
- AMP Activated Protein Kinase alpha Subunit
|
Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".
This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 5 | 5 |
| 2008 | 1 | 4 | 5 |
| 2009 | 2 | 3 | 5 |
| 2010 | 3 | 3 | 6 |
| 2011 | 6 | 4 | 10 |
| 2012 | 3 | 2 | 5 |
| 2013 | 4 | 5 | 9 |
| 2014 | 6 | 0 | 6 |
| 2015 | 2 | 1 | 3 |
| 2016 | 5 | 3 | 8 |
| 2017 | 1 | 2 | 3 |
| 2018 | 5 | 2 | 7 |
| 2019 | 6 | 2 | 8 |
| 2020 | 6 | 4 | 10 |
| 2021 | 3 | 3 | 6 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.
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CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing. Essays Biochem. 2024 Nov 18; 68(3):309-320.
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Fine-tuning AMPK in physiology and disease using point-mutant mouse models. Dis Model Mech. 2024 Aug 01; 17(8).
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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers. Mol Cell. 2024 May 16; 84(10):1964-1979.e6.
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Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies. Cancer Res Commun. 2024 02 12; 4(2):378-387.
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GSK-3? as a Potential Coordinator of Anabolic and Catabolic Pathways in Hepatitis C Virus Insulin Resistance. Intervirology. 2024; 67(1):6-18.
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Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes. Diabetes. 2023 09 01; 72(9):1214-1227.
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GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer. Cell Rep. 2022 09 20; 40(12):111344.
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Parenteral Nutrition Associated Hepatic Steatosis and NAFLD Intersect at AMPK. Cell Mol Gastroenterol Hepatol. 2022; 14(3):724-725.
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Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis. Am J Physiol Heart Circ Physiol. 2022 08 01; 323(2):H285-H300.
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TUSC2 immunogene enhances efficacy of chemo-immuno combination on KRAS/LKB1 mutant NSCLC in humanized mouse model. Commun Biol. 2022 02 24; 5(1):167.