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JEANINE VAN NOSTRAND

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
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    Collapse Research 
    Collapse research activities and funding
    R35GM146762     (VAN NOSTRAND, JEANINE L)Sep 16, 2022 - Jul 31, 2027
    NIH
    The functional role of mTORC1 regulation by AMPK in cellular metabolic reprogramming
    Role: Principal Investigator
    F31CA167917     (FREY, JEANINE L)Mar 1, 2012 - Mar 15, 2017
    NIH
    Elucidating the in vivo Role of the p53 Apoptosis-Specific Target Gene Siva
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ashraf N, Van Nostrand JL. Fine-tuning AMPK in physiology and disease using point-mutant mouse models. Dis Model Mech. 2024 Aug 01; 17(8). PMID: 39136185; PMCID: PMC11340815.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Oravecz-Wilson K, Lauder E, Taylor A, Maneix L, Van Nostrand JL, Sun Y, Li L, Zhao D, Liu C, Reddy P. Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models. J Clin Invest. 2024 Mar 01; 134(5). PMID: 38426503; PMCID: PMC10904048.
      Citations:    Fields:    Translation:AnimalsCells
    3. Hung CM, Lombardo PS, Malik N, Brun SN, Hellberg K, Van Nostrand JL, Garcia D, Baumgart J, Diffenderfer K, Asara JM, Shaw RJ. AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Sci Adv. 2021 04; 7(15). PMID: 33827825; PMCID: PMC8026119.
      Citations: 17     Fields:    
    4. Van Nostrand JL, Hellberg K, Luo EC, Van Nostrand EL, Dayn A, Yu J, Shokhirev MN, Dayn Y, Yeo GW, Shaw RJ. AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. Genes Dev. 2020 10 01; 34(19-20):1330-1344. PMID: 32912901; PMCID: PMC7528705.
      Citations: 15     Fields:    Translation:AnimalsCells
    5. Bowen ME, McClendon J, Long HK, Sorayya A, Van Nostrand JL, Wysocka J, Attardi LD. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Dev Cell. 2019 07 22; 50(2):212-228.e6. PMID: 31178404; PMCID: PMC6650355.
      Citations: 23     Fields:    Translation:AnimalsCells
    6. Jacobs SBR, Van Nostrand JL, Bowen ME, Baker JC, Attardi LD. Siva plays a critical role in mouse embryonic development. Cell Death Differ. 2020 01; 27(1):297-309. PMID: 31164717; PMCID: PMC7205994.
      Citations: 2     Fields:    Translation:Animals
    7. Van Nostrand JL, Bowen ME, Vogel H, Barna M, Attardi LD. The p53 family members have distinct roles during mammalian embryonic development. Cell Death Differ. 2017 04; 24(4):575-579. PMID: 28211873; PMCID: PMC5384018.
      Citations: 21     Fields:    Translation:Animals
    8. Svensson RU, Parker SJ, Eichner LJ, Kolar MJ, Wallace M, Brun SN, Lombardo PS, Van Nostrand JL, Hutchins A, Vera L, Gerken L, Harriman G, Westlin WF, Harwood HJ, Saghatelian A, Kapeller R, Metallo CM, Shaw RJ, Greenwood J, Bhat S. Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models. Nat Med. 2016 10; 22(10):1108-1119. PMID: 27643638; PMCID: PMC5053891.
      Citations: 171     Fields:    Translation:HumansAnimalsCells
    9. Young NP, Kamireddy A, Van Nostrand JL, Eichner LJ, Shokhirev MN, Dayn Y, Shaw RJ. AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes. Genes Dev. 2016 Mar 01; 30(5):535-52. PMID: 26944679; PMCID: PMC4782048.
      Citations: 68     Fields:    Translation:AnimalsCells
    10. Van Nostrand JL, Mello SS, Jacobs SB, Luong R, Attardi LD, Brisac A. The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development. Cancer Discov. 2015 Jun; 5(6):622-35. PMID: 25813352; PMCID: PMC4456277.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    11. Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Chang CP, Wysocka J, Martin DM, Attardi LD, Atti?-Bitach T. Inappropriate p53 activation during development induces features of CHARGE syndrome. Nature. 2014 Oct 09; 514(7521):228-32. PMID: 25119037; PMCID: PMC4192026.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    12. Van Nostrand JL, Attardi LD. Guilty as CHARGED: p53's expanding role in disease. Cell Cycle. 2014; 13(24):3798-807. PMID: 25483057; PMCID: PMC4613992.
      Citations: 12     Fields:    Translation:AnimalsCells
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