Tumor Suppressor Protein p53
"Tumor Suppressor Protein p53" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
| Descriptor ID |
D016159
|
| MeSH Number(s) |
D12.776.157.687.650 D12.776.260.820 D12.776.624.776.775 D12.776.660.720.650 D12.776.744.845
|
| Concept/Terms |
Tumor Suppressor Protein p53- Tumor Suppressor Protein p53
- p53 Antigen
- TP53 Protein
- TRP53 Protein
- p53 Tumor Suppressor Protein
- pp53 Phosphoprotein
- Phosphoprotein, pp53
- Cellular Tumor Antigen p53
- Oncoprotein p53
|
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Protein p53".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Protein p53".
This graph shows the total number of publications written about "Tumor Suppressor Protein p53" by people in this website by year, and whether "Tumor Suppressor Protein p53" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 1 | 7 |
| 1997 | 3 | 4 | 7 |
| 1998 | 2 | 7 | 9 |
| 1999 | 7 | 2 | 9 |
| 2000 | 9 | 7 | 16 |
| 2001 | 6 | 4 | 10 |
| 2002 | 8 | 4 | 12 |
| 2003 | 16 | 8 | 24 |
| 2004 | 9 | 7 | 16 |
| 2005 | 7 | 7 | 14 |
| 2006 | 5 | 5 | 10 |
| 2007 | 7 | 3 | 10 |
| 2008 | 3 | 6 | 9 |
| 2009 | 11 | 11 | 22 |
| 2010 | 13 | 5 | 18 |
| 2011 | 15 | 12 | 27 |
| 2012 | 8 | 11 | 19 |
| 2013 | 8 | 16 | 24 |
| 2014 | 17 | 11 | 28 |
| 2015 | 16 | 17 | 33 |
| 2016 | 11 | 14 | 25 |
| 2017 | 12 | 5 | 17 |
| 2018 | 15 | 6 | 21 |
| 2019 | 16 | 11 | 27 |
| 2020 | 9 | 10 | 19 |
| 2021 | 12 | 5 | 17 |
| 2022 | 3 | 10 | 13 |
| 2023 | 5 | 4 | 9 |
| 2024 | 3 | 7 | 10 |
| 2025 | 8 | 10 | 18 |
| 2026 | 1 | 4 | 5 |
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Below are the most recent publications written about "Tumor Suppressor Protein p53" by people in Profiles.
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Interpretable Active Learning for Pedigree Data Deduplication in Cancer Genetics. JCO Clin Cancer Inform. 2026 Mar; 10:e2500252.
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Final Report of a Phase II Study of Ibrutinib and Venetoclax in Previously Untreated Waldenstr?m Macroglobulinemia. Am J Hematol. 2026 06; 101(6):1255-1263.
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Spectrum, prevalence, and clinical correlates of PPM1D mutations in patients with clonal hematopoiesis and clonal cytopenias. Blood Adv. 2026 Mar 10; 10(5):1746-1755.
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Venetoclax or Pirtobrutinib in Relapsed/Refractory Waldenstr?m Macroglobulinemia: Clinical and Molecular Predictors and Sequencing Implications. Am J Hematol. 2026 May; 101(5):1045-1055.
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Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth. Mol Cancer Ther. 2026 Feb 04; 25(2):257-271.
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Establishment and characterization of a new immortalized human oral keratinocyte (HOK) cell line harboring various TP53 mutations. Oral Oncol. 2026 Jan; 172:107799.
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Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition. Commun Biol. 2025 Nov 05; 8(1):1522.
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Clonal hematopoiesis and subsequent venous thromboembolism among survivors of autologous transplantation for lymphoma. J Natl Cancer Inst. 2025 Nov 01; 117(11):2394-2398.
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Magnolol Traverses the Blood-brain Barrier and Enhances Temozolomide-induced Intrinsic Apoptosis of Glioblastoma Cells via a p53 Redox Signaling Mechanism. Anticancer Res. 2025 Nov; 45(11):5001-5017.
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Downregulation of the Tumor Suppressor P53 Gene associated with the Progression of Clinical Staging and the Incidence of Distant Metastasis in Indonesian Colorectal Cancer. Korean J Gastroenterol. 2025 10 25; 85(4):527-536.