MDS1 and EVI1 Complex Locus Protein
"MDS1 and EVI1 Complex Locus Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA binding protein, transcriptional regulator, and proto-oncogene protein that contains 10 CYS2-HIS2 ZINC FINGERS. It functions as a positive or negative regulator of expression for target genes involved in organism development.
| Descriptor ID |
D000074008
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| MeSH Number(s) |
D12.776.260.534 D12.776.624.664.700.129 D12.776.930.419
|
| Concept/Terms |
MDS1 and EVI1 Complex Locus Protein- MDS1 and EVI1 Complex Locus Protein
- Ecotropic Virus Integration Site 1 Protein Homolog
- Zinc Finger Protein Evi1
- MECOM Protein
- Myelodysplasia Syndrome-Associated Protein 1
- Myelodysplasia Syndrome Associated Protein 1
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Below are MeSH descriptors whose meaning is more general than "MDS1 and EVI1 Complex Locus Protein".
Below are MeSH descriptors whose meaning is more specific than "MDS1 and EVI1 Complex Locus Protein".
This graph shows the total number of publications written about "MDS1 and EVI1 Complex Locus Protein" by people in this website by year, and whether "MDS1 and EVI1 Complex Locus Protein" was a major or minor topic of these publications.
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Below are the most recent publications written about "MDS1 and EVI1 Complex Locus Protein" by people in Profiles.
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BCR-ABL fusion transcript types and levels and their interaction with secondary genetic changes in determining the phenotype of Philadelphia chromosome-positive leukemias. Blood. 2008 Dec 15; 112(13):5190-2.
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Aberrant EVI1 expression in acute myeloid leukemias associated with the t(3;8)(q26;q24). Cancer Genet Cytogenet. 2007 Aug; 177(1):37-42.
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Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer. Cancer Res. 2007 Apr 01; 67(7):3074-84.
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t(3;21)(q26;q22) in myeloid leukemia: an aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy. Cancer. 2006 Apr 15; 106(8):1730-8.
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Relationship between methylation of the p15 gene and ectopic expression of the EVI-1 gene in myelodysplastic syndromes (MDS). Leukemia. 2001 Jun; 15(6):990-1.