"Homeobox Protein Nkx-2.5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
| Descriptor ID |
D000072576
|
| MeSH Number(s) |
D12.776.260.400.234 D12.776.930.324
|
| Concept/Terms |
Homeobox Protein Nkx-2.5- Homeobox Protein Nkx-2.5
- Homeobox Protein Nkx 2.5
- Nkx-2.5, Homeobox Protein
- NK2 Homeobox 5 Protein
- Homeobox Transcription Factor Csx-Nkx2-5
- Homeobox Transcription Factor Csx Nkx2 5
- Homeobox Protein Csx-Nkx2.5
- Csx-Nkx2.5, Homeobox Protein
- Homeobox Protein Csx Nkx2.5
- Cardiac-Specific Homeobox Protein
- Cardiac Specific Homeobox Protein
- Homeobox Protein, Cardiac-Specific
- Transcription Factor Nkx-2.5
- Nkx-2.5, Transcription Factor
- Transcription Factor Nkx 2.5
|
Below are MeSH descriptors whose meaning is more general than "Homeobox Protein Nkx-2.5".
Below are MeSH descriptors whose meaning is more specific than "Homeobox Protein Nkx-2.5".
This graph shows the total number of publications written about "Homeobox Protein Nkx-2.5" by people in this website by year, and whether "Homeobox Protein Nkx-2.5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Homeobox Protein Nkx-2.5" by people in Profiles.
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Sall4 and Gata4 induce cardiac fibroblast transition towards a partially multipotent state with cardiogenic potential. Sci Rep. 2024 10 15; 14(1):24182.
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?1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation. Cardiovasc Res. 2024 Sep 21; 120(11):1279-1294.
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Epigenomic and Transcriptomic Dynamics During Human Heart Organogenesis. Circ Res. 2020 10 09; 127(9):e184-e209.
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Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017 Nov 07; 21(6):1562-1573.
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Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts. Genesis. 2017 08; 55(8).
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Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell. 2016 Feb 25; 164(5):999-1014.
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Curcumin induces differentiation of embryonic stem cells through possible modulation of nitric oxide-cyclic GMP pathway. Protein Cell. 2012 Jul; 3(7):535-44.
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Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature. Arterioscler Thromb Vasc Biol. 2011 Oct; 31(10):2193-202.
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Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27; 193(7):1181-96.
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Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. Clin Cancer Res. 2010 Jul 15; 16(14):3539-47.