"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
| Descriptor ID |
D051880
|
| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.770
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 4 | 4 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 4 | 7 |
| 2010 | 6 | 2 | 8 |
| 2011 | 6 | 6 | 12 |
| 2012 | 7 | 2 | 9 |
| 2013 | 7 | 5 | 12 |
| 2014 | 10 | 4 | 14 |
| 2015 | 5 | 2 | 7 |
| 2016 | 5 | 1 | 6 |
| 2017 | 2 | 2 | 4 |
| 2018 | 6 | 4 | 10 |
| 2019 | 5 | 1 | 6 |
| 2020 | 6 | 1 | 7 |
| 2021 | 3 | 0 | 3 |
| 2022 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations. Clin Cancer Res. 2019 02 15; 25(4):1280-1290.
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LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun. 2018 10 10; 9(1):4055.
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Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults. Blood. 2017 07 13; 130(2):167-175.
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Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing. PLoS One. 2016; 11(12):e0167286.
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Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. J Clin Invest. 2016 07 01; 126(7):2626-41.
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Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells. Nat Commun. 2014 Jul 22; 5:4416.
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Notch3 pathway alterations in ovarian cancer. Cancer Res. 2014 Jun 15; 74(12):3282-93.
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Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol. 2014 Jan; 12(1):e1001777.
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Introduction to Notch signaling. Methods Mol Biol. 2014; 1187:1-14.
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A high Notch pathway activation predicts response to ? secretase inhibitors in proneural subtype of glioma tumor-initiating cells. Stem Cells. 2014 Jan; 32(1):301-12.