"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
| Descriptor ID |
D051880
|
| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.770
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 4 | 7 |
| 2010 | 6 | 2 | 8 |
| 2011 | 6 | 6 | 12 |
| 2012 | 7 | 2 | 9 |
| 2013 | 7 | 5 | 12 |
| 2014 | 10 | 4 | 14 |
| 2015 | 5 | 2 | 7 |
| 2016 | 5 | 2 | 7 |
| 2017 | 2 | 3 | 5 |
| 2018 | 6 | 4 | 10 |
| 2019 | 5 | 1 | 6 |
| 2020 | 6 | 1 | 7 |
| 2021 | 3 | 0 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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The Notch pathway: A guardian of cell fate during neurogenesis. Curr Opin Cell Biol. 2025 Aug; 95:102543.
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Dichotomous roles of ACBD3 in NSCLC growth and metastasis. Oncogene. 2025 Jul; 44(25):2078-2090.
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Bi-directional signaling between the intestinal epithelium and type-3 innate lymphoid cells regulates secretory dynamics and interleukin-22. Mucosal Immunol. 2024 Feb; 17(1):1-12.
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Notch Missense Mutations in Drosophila Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling. Biomolecules. 2022 11 25; 12(12).
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TM2D genes regulate Notch signaling and neuronal function in Drosophila. PLoS Genet. 2021 12; 17(12):e1009962.
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Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Dev Cell. 2021 09 13; 56(17):2471-2485.e5.
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Multifaceted regulation of Notch signaling by glycosylation. Glycobiology. 2021 01 09; 31(1):8-28.
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UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. Am J Hum Genet. 2021 01 07; 108(1):134-147.
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Post-Developmental Roles of Notch Signaling in the Nervous System. Biomolecules. 2020 07 01; 10(7).
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Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Dev Biol. 2020 06 01; 462(1):74-84.