"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
| Descriptor ID |
D051880
|
| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.770
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 5 | 8 |
| 2010 | 6 | 2 | 8 |
| 2011 | 6 | 6 | 12 |
| 2012 | 7 | 2 | 9 |
| 2013 | 7 | 6 | 13 |
| 2014 | 10 | 4 | 14 |
| 2015 | 6 | 2 | 8 |
| 2016 | 5 | 2 | 7 |
| 2017 | 3 | 3 | 6 |
| 2018 | 6 | 4 | 10 |
| 2019 | 5 | 1 | 6 |
| 2020 | 6 | 1 | 7 |
| 2021 | 3 | 1 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 2 | 3 |
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click here.
Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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The Notch pathway: A guardian of cell fate during neurogenesis. Curr Opin Cell Biol. 2025 Aug; 95:102543.
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Dichotomous roles of ACBD3 in NSCLC growth and metastasis. Oncogene. 2025 Jul; 44(25):2078-2090.
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Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nat Commun. 2025 Mar 26; 16(1):2974.
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Bi-directional signaling between the intestinal epithelium and type-3 innate lymphoid cells regulates secretory dynamics and interleukin-22. Mucosal Immunol. 2024 Feb; 17(1):1-12.
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Notch Missense Mutations in Drosophila Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling. Biomolecules. 2022 11 25; 12(12).
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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling. Cell Death Dis. 2022 08 05; 13(8):678.
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Interruption of Klf5 acetylation in basal progenitor cells promotes luminal commitment by activating Notch signaling. J Genet Genomics. 2022 06; 49(6):579-582.
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TM2D genes regulate Notch signaling and neuronal function in Drosophila. PLoS Genet. 2021 12; 17(12):e1009962.
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Notch Signaling and MicroRNA: The Dynamic Duo Steering Between Neurogenesis and Glioblastomas. Cell Mol Biol (Noisy-le-grand). 2021 Aug 15; 67(2):33-43.
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Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Dev Cell. 2021 09 13; 56(17):2471-2485.e5.