"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
| Descriptor ID |
D051880
|
| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.770
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 1 | 4 | 5 |
| 2007 | 3 | 3 | 6 |
| 2008 | 3 | 3 | 6 |
| 2009 | 5 | 6 | 11 |
| 2010 | 13 | 3 | 16 |
| 2011 | 13 | 9 | 22 |
| 2012 | 10 | 3 | 13 |
| 2013 | 12 | 8 | 20 |
| 2014 | 14 | 4 | 18 |
| 2015 | 5 | 2 | 7 |
| 2016 | 7 | 3 | 10 |
| 2017 | 5 | 3 | 8 |
| 2018 | 8 | 8 | 16 |
| 2019 | 8 | 3 | 11 |
| 2020 | 8 | 1 | 9 |
| 2021 | 4 | 2 | 6 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling. Cell Death Dis. 2022 08 05; 13(8):678.
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TM2D genes regulate Notch signaling and neuronal function in Drosophila. PLoS Genet. 2021 12; 17(12):e1009962.
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Notch Signaling and MicroRNA: The Dynamic Duo Steering Between Neurogenesis and Glioblastomas. Cell Mol Biol (Noisy-le-grand). 2021 Aug 15; 67(2):33-43.
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Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Dev Cell. 2021 09 13; 56(17):2471-2485.e5.
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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte ?-selection. Elife. 2021 07 09; 10.
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Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers. Molecules. 2021 Feb 07; 26(4).
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Multifaceted regulation of Notch signaling by glycosylation. Glycobiology. 2021 01 09; 31(1):8-28.
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Notch Signaling & MicroRNAs - two tumblers of neurogenesis and Gliomas. J Pak Med Assoc. 2021 Jan; 71(1(B)):310-318.
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UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. Am J Hum Genet. 2021 01 07; 108(1):134-147.
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Post-Developmental Roles of Notch Signaling in the Nervous System. Biomolecules. 2020 07 01; 10(7).