"Endoglin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
| Descriptor ID |
D000071063
|
| MeSH Number(s) |
D12.776.543.750.250
|
| Concept/Terms |
Endoglin- Endoglin
- CD105 Antigen
- Antigen, CD105
- Endoglin Protein
|
Below are MeSH descriptors whose meaning is more general than "Endoglin".
Below are MeSH descriptors whose meaning is more specific than "Endoglin".
This graph shows the total number of publications written about "Endoglin" by people in this website by year, and whether "Endoglin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endoglin" by people in Profiles.
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Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas. Cancer Immunol Res. 2025 Oct 01; 13(10):1591-1608.
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Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Clin Cancer Res. 2013 Jan 01; 19(1):170-82.
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Novel 9q34.11 gene deletions encompassing combinations of four Mendelian disease genes: STXBP1, SPTAN1, ENG, and TOR1A. Genet Med. 2012 Oct; 14(10):868-76.
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Circulating endoglin concentration is not elevated in chronic kidney disease. PLoS One. 2011; 6(8):e23718.
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Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome. Oncogene. 2011 Mar 03; 30(9):1046-58.
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GATA transcription in a small rhodamine 123(low)CD34(+) subpopulation of a peripheral blood-derived CD34(-)CD105(+) mesenchymal cell line. Exp Hematol. 2002 Aug; 30(8):887-95.
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TGF-beta receptor signaling. Biochim Biophys Acta. 1997 Oct 24; 1333(2):F105-50.