"Endoglin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
| Descriptor ID |
D000071063
|
| MeSH Number(s) |
D12.776.543.750.250
|
| Concept/Terms |
Endoglin- Endoglin
- CD105 Antigen
- Antigen, CD105
- Endoglin Protein
|
Below are MeSH descriptors whose meaning is more general than "Endoglin".
Below are MeSH descriptors whose meaning is more specific than "Endoglin".
This graph shows the total number of publications written about "Endoglin" by people in this website by year, and whether "Endoglin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Endoglin" by people in Profiles.
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Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas. Cancer Immunol Res. 2025 Oct 01; 13(10):1591-1608.
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Pravastatin Protects Cytotrophoblasts from Hyperglycemia-Induced Preeclampsia Phenotype. Cells. 2024 09 13; 13(18).
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Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. Hepatology. 2023 02 01; 77(2):530-545.
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Preeclampsia at delivery is associated with lower serum vitamin D and higher antiangiogenic factors: a case control study. Reprod Biol Endocrinol. 2022 Jan 06; 20(1):8.
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Ticagrelor Improves Remodeling, Reduces Apoptosis, Inflammation and Fibrosis and Increases the Number of Progenitor Stem Cells After Myocardial Infarction in a Rat Model of Ischemia Reperfusion. Cell Physiol Biochem. 2019; 53(6):961-981.
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Endoglin (CD105) coordinates the process of endometrial receptivity for embryo implantation. Mol Cell Endocrinol. 2016 Apr 15; 425:69-83.
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Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics. PLoS One. 2015; 10(9):e0137175.
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Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy. J Biol Chem. 2015 Jun 12; 290(24):14884-92.
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Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. J Biol Chem. 2014 Sep 12; 289(37):25486-96.
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Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Clin Cancer Res. 2013 Jan 01; 19(1):170-82.