"Receptor, Notch1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051881
|
| MeSH Number(s) |
D12.776.543.750.725.500 D12.776.930.770.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch1".
This graph shows the total number of publications written about "Receptor, Notch1" by people in this website by year, and whether "Receptor, Notch1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 2 | 1 | 3 |
| 2006 | 3 | 0 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 4 | 1 | 5 |
| 2009 | 6 | 1 | 7 |
| 2010 | 2 | 2 | 4 |
| 2011 | 5 | 3 | 8 |
| 2012 | 4 | 2 | 6 |
| 2013 | 7 | 2 | 9 |
| 2014 | 3 | 4 | 7 |
| 2015 | 5 | 5 | 10 |
| 2016 | 4 | 2 | 6 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 4 | 7 |
| 2019 | 4 | 1 | 5 |
| 2020 | 1 | 2 | 3 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 6 | 7 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Notch1" by people in Profiles.
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Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma. Invest Ophthalmol Vis Sci. 2024 Sep 03; 65(11):4.
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Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer. Oncologist. 2022 12 09; 27(12):1004-e926.
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Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma. Cancer Res. 2022 12 02; 82(23):4444-4456.
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Notch1 signaling in keratocytes maintains corneal transparency by suppressing VEGF expression. Stem Cell Reports. 2022 06 14; 17(6):1442-1457.
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Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nat Commun. 2022 05 19; 13(1):2801.
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Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia. Leuk Res. 2022 05; 116:106827.
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Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL. Leukemia. 2022 05; 36(5):1261-1273.
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Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis. Am J Hematol. 2022 03 01; 97(3):E100-E102.
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The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis. Cells. 2021 08 25; 10(9).
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Prognostic impact of Notch1 receptor and clinicopathological High-Risk Predictors in lacrimal gland adenoid cystic carcinoma. Acta Ophthalmol. 2021 Dec; 99(8):e1467-e1473.