"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
|
| MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 4 | 4 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 5 | 5 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 7 | 7 |
| 2005 | 1 | 14 | 15 |
| 2006 | 0 | 23 | 23 |
| 2007 | 1 | 19 | 20 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 16 | 16 |
| 2010 | 0 | 22 | 22 |
| 2011 | 0 | 16 | 16 |
| 2012 | 1 | 19 | 20 |
| 2013 | 0 | 18 | 18 |
| 2014 | 0 | 13 | 13 |
| 2015 | 1 | 18 | 19 |
| 2016 | 0 | 21 | 21 |
| 2017 | 1 | 15 | 16 |
| 2018 | 0 | 18 | 18 |
| 2019 | 0 | 14 | 14 |
| 2020 | 1 | 12 | 13 |
| 2021 | 0 | 12 | 12 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 9 | 9 |
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click here.
Below are the most recent publications written about "Methylation" by people in Profiles.
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Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation. J Mol Biol. 2024 Apr 01; 436(7):168371.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.
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Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Nat Methods. 2023 10; 20(10):1483-1492.
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H3K36 methylation maintains cell identity by regulating opposing lineage programmes. Nat Cell Biol. 2023 Aug; 25(8):1121-1134.
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An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability. Elife. 2023 05 19; 12.
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Effectors and effects of arginine methylation. Biochem Soc Trans. 2023 04 26; 51(2):725-734.
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Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures. Oncologist. 2023 04 06; 28(4):368-372.
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Association of IFITM1 Promoter Methylation with Severity of SARS-CoV-2 Infection. Clin Lab. 2023 Apr 01; 69(4).
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Histone H4 proteoforms and post-translational modifications in the Mus musculus brain with quantitative comparison of ages and brain regions. Anal Bioanal Chem. 2023 Apr; 415(9):1627-1639.
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A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J Biol Chem. 2023 02; 299(2):102862.