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CHERYL WALKER

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleDirector
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Epidemiology & Populat Sci


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    P30ES030285     (ELFERINK, CORNELIS JOHAN;WALKER, CHERYL L.)May 15, 2019 - Mar 31, 2024
    NIH
    Gulf Coast Center for Precision Environmental Health
    Role: Principal Investigator
    R35CA231993     (WALKER, CHERYL L.)Aug 1, 2018 - Jul 31, 2025
    NIH
    A New Target for Chromatin Remodeler Defects in Cancer
    Role: Principal Investigator
    T32ES027801     (WALKER, CHERYL L.)Jul 1, 2018 - Jun 30, 2023
    NIH
    Training in Precision Environmental Health Sciences
    Role: Principal Investigator
    R21ES029493     (PETROSINO, JOSEPH FRANK)Mar 1, 2018 - Feb 28, 2021
    NIH
    Incorporating the Microbiome into DR2 Activities to Inform Health Outcomes
    Role: Co-Principal Investigator
    R01ES028615     (AL-HENDY, AYMAN)Sep 15, 2017 - Jul 31, 2023
    NIH
    Gene X Environment Interactions in the Pathogenesis of Uterine Fibroids
    Role: Co-Principal Investigator
    R01CA203012     (RATHMELL, W. KIMRYN)Jul 1, 2016 - Jun 30, 2021
    NIH
    Methyltransferase Contributions to Genomic Stability and Cancer
    Role: Co-Principal Investigator
    U01ES026719     (WALKER, CHERYL L)Jun 1, 2016 - Apr 30, 2021
    NIH
    Epigenetic Signatures of Developmental Reprogramming in Target and Surrogate Tissues
    Role: Principal Investigator
    R01ES023206     (WALKER, CHERYL L)Sep 1, 2013 - May 31, 2018
    NIH
    Epigenetic Programmers Targeted During Developmental Reprogramming
    Role: Principal Investigator
    R13HD072606     (WALKER, CHERYL L)May 14, 2012 - May 13, 2013
    NIH
    PPTOX III: Environmental Stressors in the Developmental Origins of Disease: Evide
    Role: Principal Investigator
    R21ES020055     (WALKER, CHERYL L)Jun 9, 2011 - May 31, 2013
    NIH
    Reversing the Effects of Developmental Reprogramming
    Role: Principal Investigator
    R01CA143811     (WALKER, CHERYL L)Jan 25, 2010 - Jul 31, 2020
    NIH
    Tumor Suppressor Localization and Function at the Peroxisome
    Role: Principal Investigator
    RC2ES018789     (WALKER, CHERYL L.)Sep 24, 2009 - Jul 31, 2013
    NIH
    Developmental Reprogramming of Prostate Carcinogenesis by BPA
    Role: Co-Principal Investigator
    R01HD046282     (WALKER, CHERYL L)Sep 24, 2003 - Jul 31, 2009
    NIH
    Molecular Etiology of Leiomyoma Uteri
    Role: Principal Investigator
    R13ES009751     (WALKER, CHERYL L)Jul 24, 1998 - Jul 23, 1999
    NIH
    MECHANISMS OF TOXICITY GORDON CONFERENCE
    Role: Principal Investigator
    R01ES008263     (WALKER, CHERYL L)Aug 1, 1996 - Feb 28, 2014
    NIH
    Environmental Estrogens and Uterine Leiomyoma
    Role: Principal Investigator
    R01CA072253     (WALKER, CHERYL L)May 1, 1996 - Apr 30, 2001
    NIH
    PRECLINICAL THERAPEUTIC STUDIES IN RAT LEIOMYOMA MODEL
    Role: Principal Investigator
    R41HD033605     (WALKER, CHERYL L)Sep 30, 1995 - Sep 30, 1996
    NIH
    MODEL FOR SCREENING ANTIHORMONAL THERAPIES FOR LEIOMYOMA
    Role: Principal Investigator
    R13CA065923     (WALKER, CHERYL L)Sep 30, 1994 - Sep 29, 1995
    NIH
    INTERNATIONAL CONFERENCE--CARCINOGENESIS/RISK ASSESSMENT
    Role: Principal Investigator
    R01CA063613     (WALKER, CHERYL L)Jun 3, 1994 - Mar 31, 2010
    NIH
    Genetic Determinants of Rat Renal Carcinogenesis
    Role: Principal Investigator
    R01ES006658     (WALKER, CHERYL L)Feb 9, 1994 - Jan 31, 1999
    NIH
    WILM'S TUMOR SUPPRESSOR GENE IN MESOTHELIOMA
    Role: Principal Investigator
    P30ES023512     (CHAPKIN, ROBERT STEPHEN)Mar 31, 2018
    NIH
    FC1: QUANTITATIVE BIOLOGY
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chowdhury P, Wang X, Love JF, Vargas-Hernandez S, Nakatani Y, Grimm SL, Mezquita D, Mason FM, Martinez ED, Coarfa C, Walker CL, Gustavsson AK, Dere R. Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability. bioRxiv. 2024 Feb 21. PMID: 38464252; PMCID: PMC10925129.
      Citations:    
    2. Mason FM, Kounlavong ES, Tebeje AT, Dahiya R, Guess T, Khan A, Vlach L, Norris SR, Lovejoy CA, Dere R, Strahl BD, Ohi R, Ly P, Walker CL, Rathmell WK. SETD2 safeguards the genome against isochromosome formation. Proc Natl Acad Sci U S A. 2023 09 26; 120(39):e2303752120. PMID: 37722039; PMCID: PMC10523680.
      Citations:    Fields:    Translation:HumansCells
    3. Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A. TGF? signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Cell Mol Life Sci. 2023 Sep 09; 80(10):288. PMID: 37689587; PMCID: PMC10492698.
      Citations: 4     Fields:    Translation:AnimalsCells
    4. Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A. TGF? signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Res Sq. 2023 Jun 07. PMID: 37333266; PMCID: PMC10274956.
      Citations:    
    5. Soeung M, Perelli L, Chen Z, Dondossola E, Ho IL, Carbone F, Zhang L, Khan H, Le CN, Zhu C, Peoples MD, Feng N, Jiang S, Zacharias NM, Minelli R, Shapiro DD, Deem AK, Gao S, Cheng EH, Lucchetti D, Walker CL, Carugo A, Giuliani V, Heffernan TP, Viale A, Tannir NM, Draetta GF, Msaouel P, Genovese G. SMARCB1 regulates the hypoxic stress response in sickle cell trait. Proc Natl Acad Sci U S A. 2023 05 23; 120(21):e2209639120. PMID: 37186844; PMCID: PMC10214195.
      Citations: 2     Fields:    Translation:HumansAnimals
    6. Shapiro DD, Zacharias NM, Tripathi DN, Karki M, Bertocchio JP, Soeung M, He R, Westerman ME, Gao J, Rao P, Lam TNA, Jonasch E, Perelli L, Cheng EH, Carugo A, Heffernan TP, Walker CL, Genovese G, Tannir NM, Karam JA, Msaouel P. Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy. Clin Transl Med. 2023 05; 13(5):e1267. PMID: 37226898; PMCID: PMC10210052.
      Citations: 2     Fields:    Translation:Humans
    7. Baccarelli A, Dolinoy DC, Walker CL. A precision environmental health approach to prevention of human disease. Nat Commun. 2023 04 28; 14(1):2449. PMID: 37117186; PMCID: PMC10147599.
      Citations: 2     Fields:    Translation:Humans
    8. Laufer BI, Hasegawa Y, Zhang Z, Hogrefe CE, Del Rosso LA, Haapanen L, Hwang H, Bauman MD, Van de Water J, Taha AY, Slupsky CM, Golub MS, Capitanio JP, VandeVoort CA, Walker CK, LaSalle JM. Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models. Nat Commun. 2022 09 21; 13(1):5538. PMID: 36130949; PMCID: PMC9492781.
      Citations:    
    9. Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM, Gutierrez Fug?n OJ. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Genome Biol. 2022 02 16; 23(1):46. PMID: 35168652; PMCID: PMC8848662.
      Citations: 1     Fields:    Translation:HumansCells
    10. Shapiro DD, Soeung M, Perelli L, Dondossola E, Surasi DS, Tripathi DN, Bertocchio JP, Carbone F, Starbuck MW, Van Alstine ML, Rao P, Katz MHG, Parker NH, Shah AY, Carugo A, Heffernan TP, Schadler KL, Logothetis C, Walker CL, Wood CG, Karam JA, Draetta GF, Tannir NM, Genovese G, Msaouel P. Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies. Cancers (Basel). 2021 Nov 30; 13(23). PMID: 34885132; PMCID: PMC8656882.
      Citations: 2     
    11. Koenning M, Wang X, Karki M, Jangid RK, Kearns S, Tripathi DN, Cianfrocco M, Verhey KJ, Jung SY, Coarfa C, Ward CS, Kalish BT, Grimm SL, Rathmell WK, Mostany R, Dere R, Rasband MN, Walker CL, Park IY. Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice. Brain. 2021 09 04; 144(8):2527-2540. PMID: 34014281; PMCID: PMC8418347.
      Citations: 2     Fields:    Translation:AnimalsCells
    12. Kearns S, Mason FM, Rathmell WK, Park IY, Walker C, Verhey KJ, Cianfrocco MA. Molecular determinants for a-tubulin methylation by SETD2. J Biol Chem. 2021 07; 297(1):100898. PMID: 34157286; PMCID: PMC8294582.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    13. Karki M, Jangid RK, Anish R, Seervai RNH, Bertocchio JP, Hotta T, Msaouel P, Jung SY, Grimm SL, Coarfa C, Weissman BE, Ohi R, Verhey KJ, Hodges HC, Burggren W, Dere R, Park IY, Prasad BVV, Rathmell WK, Walker CL, Tripathi DN. A cytoskeletal function for PBRM1 reading methylated microtubules. Sci Adv. 2021 04; 7(14). PMID: 33811077.
      Citations: 3     Fields:    Translation:Cells
    14. Symanski E, An Han H, Han I, McDaniel M, Whitworth KW, McCurdy S, Perkison WB, Rammah A, Lewis PGT, Delclos GL, Craft E, Bondy M, Walker CL, Hopkins L, James D, Cede?o Laurent JG. Responding to Natural and Industrial Disasters: Partnerships and Lessons Learned. Disaster Med Public Health Prep. 2022 06; 16(3):885-888. PMID: 33722331; PMCID: PMC8443687.
      Citations: 2     Fields:    
    15. Oluyomi AO, Panthagani K, Sotelo J, Gu X, Armstrong G, Luo DN, Hoffman KL, Rohlman D, Tidwell L, Hamilton WJ, Symanski E, Anderson K, Petrosino JF, Walker CL, Bondy M. Houston hurricane Harvey health (Houston-3H) study: assessment of allergic symptoms and stress after hurricane Harvey flooding. Environ Health. 2021 01 19; 20(1):9. PMID: 33468146; PMCID: PMC7816385.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    16. Jonasch E, Walker CL, Rathmell WK. Clear cell renal cell carcinoma ontogeny and mechanisms of lethality. Nat Rev Nephrol. 2021 04; 17(4):245-261. PMID: 33144689; PMCID: PMC8172121.
      Citations: 61     Fields:    Translation:Humans
    17. Seervai RNH, Grimm SL, Jangid RK, Tripathi DN, Coarfa C, Walker CL. An actin-WHAMM interaction linking SETD2 and autophagy. Biochem Biophys Res Commun. 2021 06 18; 558:202-208. PMID: 33036756; PMCID: PMC8021614.
      Citations:    Fields:    Translation:HumansCells
    18. Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL. The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase. Sci Adv. 2020 10; 6(40). PMID: 33008892; PMCID: PMC7852384.
      Citations: 6     Fields:    Translation:Cells
    19. Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker CL, Moorthy B, Lingappan K. Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox Biol. 2020 10; 37:101718. PMID: 32961439; PMCID: PMC7509469.
      Citations: 8     Fields:    Translation:Animals
    20. Walker C, Burggren W. Remodeling the epigenome and (epi)cytoskeleton: a new paradigm for co-regulation by methylation. J Exp Biol. 2020 07 03; 223(Pt 13). PMID: 32620673; PMCID: PMC7338266.
      Citations: 5     Fields:    Translation:Cells
    21. Msaouel P, Walker CL, Genovese G, Tannir NM. Molecular hallmarks of renal medullary carcinoma: more to c-MYC than meets the eye. Mol Cell Oncol. 2020; 7(5):1777060. PMID: 32944636; PMCID: PMC7469578.
      Citations: 4     
    22. Dong J, Kaushal A, Katz TA, Jangid RK, Robertson MJ, Grimm SL, Ambati CSR, Putluri V, Cox AR, Kim KH, May TD, Gallo MR, Moore DD, Hartig SM, Foulds CE, Putluri N, Coarfa C, Walker CL, Trevi?o LS. Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood. Nat Commun. 2020 05 08; 11(1):2316. PMID: 32385268; PMCID: PMC7210260.
      Citations: 16     Fields:    Translation:AnimalsCells
    23. Msaouel P, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Karki M, Seervai RNH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM, Malouf GG, Pili? PG, Vokshi BH, Davidson I. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. 2020 05 11; 37(5):720-734.e13. PMID: 32359397; PMCID: PMC7288373.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    24. Katz TA, Grimm SL, Kaushal A, Dong J, Jangid RK, Bertocchio JP, Guan Y, Robertson MJ, Cabrera RM, Finegold MJ, Foulds CE, Coarfa C, Walker CL, Trevi?o LS, Gait?n AV. Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin. Environ Health Perspect. 2020 01; 128(1):17010. PMID: 31939706; PMCID: PMC7015627.
      Citations: 2     Fields:    Translation:HumansAnimals
    25. Terzo EA, Lim AR, Chytil A, Chiang YC, Farmer L, Gessner KH, Walker CL, Jansen VM, Rathmell WK. Correction: SETD2 loss sensitizes cells to PI3K? and AKT inhibition. Oncotarget. 2019 Oct 29; 10(59):6391-6392. PMID: 31695846; PMCID: PMC6824879.
      Citations:    Fields:    
    26. Stuebe AM, Meltzer-Brody S, Propper C, Pearson B, Beiler P, Elam M, Walker C, Mills-Koonce R, Grewen K. The Mood, Mother, and Infant Study: Associations Between Maternal Mood in Pregnancy and Breastfeeding Outcome. Breastfeed Med. 2019 10; 14(8):551-559. PMID: 31424266; PMCID: PMC6791474.
      Citations: 9     Fields:    Translation:Humans
    27. Zhu Y, Mordaunt CE, Yasui DH, Marathe R, Coulson RL, Dunaway KW, Jianu JM, Walker CK, Ozonoff S, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. Hum Mol Genet. 2019 08 15; 28(16):2659-2674. PMID: 31009952; PMCID: PMC6687952.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    28. Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W. SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nat Genet. 2019 05; 51(5):844-856. PMID: 31040401.
      Citations: 73     Fields:    Translation:AnimalsCells
    29. Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G, Malouf GG, Sgambato A. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019 02 11; 35(2):204-220.e9. PMID: 30753823; PMCID: PMC7876656.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    30. Terzo EA, Lim AR, Chytil A, Chiang YC, Farmer L, Gessner KH, Walker CL, Jansen VM, Rathmell WK. SETD2 loss sensitizes cells to PI3K? and AKT inhibition. Oncotarget. 2019 Jan 18; 10(6):647-659. PMID: 30774762; PMCID: PMC6363018.
      Citations: 2     Fields:    
    31. Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. Environ Health Perspect. 2018 11; 126(11):117004. PMID: 30465702; PMCID: PMC6371714.
      Citations: 38     Fields:    Translation:HumansPHPublic Health
    32. Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT, Trevi?o LS. CARM1 methylates MED12 to regulate its RNA-binding ability. Life Sci Alliance. 2018 Oct; 1(5):e201800117. PMID: 30456381; PMCID: PMC6238599.
      Citations: 19     Fields:    
    33. Msaouel P, Hong AL, Mullen EA, Atkins MB, Walker CL, Lee CH, Carden MA, Genovese G, Linehan WM, Rao P, Merino MJ, Grodman H, Dome JS, Fernandez CV, Geller JI, Apolo AB, Daw NC, Hodges HC, Moxey-Mims M, Wei D, Bottaro DP, Staehler M, Karam JA, Rathmell WK, Tannir NM. Updated Recommendations on the Diagnosis, Management, and Clinical Trial Eligibility Criteria for Patients With Renal Medullary Carcinoma. Clin Genitourin Cancer. 2019 02; 17(1):1-6. PMID: 30287223; PMCID: PMC6348017.
      Citations: 13     Fields:    Translation:Humans
    34. Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK. SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma. Cancer Res. 2018 06 15; 78(12):3135-3146. PMID: 29724720; PMCID: PMC6004258.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    35. Wang T, Pehrsson EC, Purushotham D, Li D, Zhuo X, Zhang B, Lawson HA, Province MA, Krapp C, Lan Y, Coarfa C, Katz TA, Tang WY, Wang Z, Biswal S, Rajagopalan S, Colacino JA, Tsai ZT, Sartor MA, Neier K, Dolinoy DC, Pinto J, Hamanaka RB, Mutlu GM, Patisaul HB, Aylor DL, Crawford GE, Wiltshire T, Chadwick LH, Duncan CG, Garton AE, McAllister KA, TaRGET II Consortium, Bartolomei MS, Walker CL, Tyson FL. The NIEHS TaRGET II Consortium and environmental epigenomics. Nat Biotechnol. 2018 03 06; 36(3):225-227. PMID: 29509741; PMCID: PMC5991835.
      Citations: 35     Fields:    Translation:HumansPHPublic Health
    36. Msaouel P, Tannir NM, Walker CL. A Model Linking Sickle Cell Hemoglobinopathies and SMARCB1 Loss in Renal Medullary Carcinoma. Clin Cancer Res. 2018 05 01; 24(9):2044-2049. PMID: 29440190.
      Citations: 20     Fields:    Translation:HumansAnimals
    37. Walker CL, Pomatto LCD, Tripathi DN, Davies KJA. Redox Regulation of Homeostasis and Proteostasis in Peroxisomes. Physiol Rev. 2018 01 01; 98(1):89-115. PMID: 29167332; PMCID: PMC6335096.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    38. Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, Saffery R, Taylor JA, Teschendorff AE, Ushijima T, Vineis P, Walker CL, Waterland RA, Wiemels J, Ambatipudi S, Degli Esposti D, Hernandez-Vargas H. Roadmap for investigating epigenome deregulation and environmental origins of cancer. Int J Cancer. 2018 03 01; 142(5):874-882. PMID: 28836271; PMCID: PMC6027626.
      Citations: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    39. Sun M, Tong P, Kong W, Dong B, Huang Y, Park IY, Zhou L, Liu XD, Ding Z, Zhang X, Bai S, German P, Powell R, Wang Q, Tong X, Tannir NM, Matin SF, Rathmell WK, Fuller GN, McCutcheon IE, Walker CL, Wang J, Jonasch E. HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas. Cancer Res. 2017 10 01; 77(19):5313-5326. PMID: 28807937; PMCID: PMC5626626.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    40. Szafran AT, Stossi F, Mancini MG, Walker CL, Mancini MA. Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis. PLoS One. 2017; 12(7):e0180141. PMID: 28704378; PMCID: PMC5509144.
      Citations: 11     Fields:    Translation:HumansCells
    41. Beckermann KE, Sharma D, Chaturvedi S, Msaouel P, Abboud MR, Allory Y, Bourdeaut F, Calderaro J, de Cubas AA, Derebail VK, Hong AL, Naik RP, Malouf GG, Mullen EA, Reuter VE, Roberts CWM, Walker CL, Wood CG, DeBaun MR, Van Poppel H, Tannir NM, Rathmell WK. Renal Medullary Carcinoma: Establishing Standards in Practice. J Oncol Pract. 2017 07; 13(7):414-421. PMID: 28697319; PMCID: PMC5508447.
      Citations: 18     Fields:    Translation:Humans
    42. Foulds CE, York B, Walker CL, Trevi?o LS. Endocrine-disrupting chemicals and fatty liver disease. Nat Rev Endocrinol. 2017 08; 13(8):445-457. PMID: 28524171; PMCID: PMC5657429.
      Citations: 59     Fields:    Translation:HumansAnimals
    43. Espejo AB, Gao G, Black K, Gayatri S, Veland N, Kim J, Chen T, Sudol M, Walker C, Bedford MT. PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch. J Biol Chem. 2017 02 10; 292(6):2255-2265. PMID: 28031468; PMCID: PMC5313098.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    44. Schroeder DI, Schmidt RJ, Crary-Dooley FK, Walker CK, Ozonoff S, Tancredi DJ, Hertz-Picciotto I, LaSalle JM. Placental methylome analysis from a prospective autism study. Mol Autism. 2016; 7:51. PMID: 28018572; PMCID: PMC5159983.
      Citations: 19     Fields:    Translation:HumansCells
    45. Mas A, Stone L, O'Connor PM, Yang Q, Kleven D, Simon C, Walker CL, Al-Hendy A. Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis. Stem Cells. 2017 03; 35(3):666-678. PMID: 27739139.
      Citations: 20     Fields:    Translation:HumansAnimalsPHPublic Health
    46. Park IY, Chowdhury P, Tripathi DN, Powell RT, Dere R, Terzo EA, Rathmell WK, Walker CL. Methylated a-tubulin antibodies recognize a new microtubule modification on mitotic microtubules. MAbs. 2016 Nov/Dec; 8(8):1590-1597. PMID: 27594515; PMCID: PMC5098444.
      Citations: 10     Fields:    Translation:HumansCells
    47. Katz TA, Yang Q, Walker CL, Al-Hendy A, Trevi?o LS. Endocrine-disrupting chemicals and uterine fibroids. Fertil Steril. 2016 09 15; 106(4):967-77. PMID: 27553264; PMCID: PMC5051569.
      Citations: 16     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    48. Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL. Dual Chromatin and Cytoskeletal Remodeling by SETD2. Cell. 2016 Aug 11; 166(4):950-962. PMID: 27518565; PMCID: PMC5101839.
      Citations: 86     Fields:    Translation:HumansCells
    49. Walker CL. Minireview: Epigenomic Plasticity and Vulnerability to EDC Exposures. Mol Endocrinol. 2016 Aug; 30(8):848-55. PMID: 27355193; PMCID: PMC4965844.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    50. Krakowiak P, Walker CK, Tancredi D, Hertz-Picciotto I, Van de Water J. Autism-specific maternal anti-fetal brain autoantibodies are associated with metabolic conditions. Autism Res. 2017 Jan; 10(1):89-98. PMID: 27312731; PMCID: PMC5164872.
      Citations: 11     Fields:    Translation:Humans
    51. Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol. 2016 Aug; 30(8):856-71. PMID: 27219490; PMCID: PMC4965842.
      Citations: 37     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    52. Tripathi DN, Walker CL. The peroxisome as a cell signaling organelle. Curr Opin Cell Biol. 2016 Apr; 39:109-12. PMID: 26967755; PMCID: PMC5657427.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    53. Tripathi DN, Zhang J, Jing J, Dere R, Walker CL. A new role for ATM in selective autophagy of peroxisomes (pexophagy). Autophagy. 2016; 12(4):711-2. PMID: 27050462; PMCID: PMC4836024.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    54. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Akematsu T, Akporiaye ET, Al-Rubeai M, Albanese C, Albani D, Albert ML, Aldudo J, Alirezaei M, Alloza I, Almasan A, Alnemri ES, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bao H, Barrachina MD, Barreiro E, Bartel B, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beck GR, Beckham JD, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernassola F, Bertolotti A, Bess AS, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bingol B, Bird SW, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Bonaldo P, Bordi M, Boulton ME, Bouret SG, Bozhkov PV, Brady N, Braga VM, Brancolini C, Brennan LA, Bresnick EH, Brest P, Bridges D, Brini M, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burke RE, Burmeister M, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Campanella M, Campbell GR, Campbell M, Campello S, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carroll B, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cervia D, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clarke PG, Clarke R, Clementi E, Cnop M, Cocco T, Cohen EE, Colecchia D, Coletto L, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
      Citations: 2567     Fields:    Translation:HumansAnimals
    55. Sowers JL, Mirfattah B, Xu P, Tang H, Park IY, Walker C, Wu P, Laezza F, Sowers LC, Zhang K. Quantification of histone modifications by parallel-reaction monitoring: a method validation. Anal Chem. 2015 Oct 06; 87(19):10006-14. PMID: 26356480; PMCID: PMC7986961.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    56. Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015 Oct; 17(10):1259-1269. PMID: 26344566; PMCID: PMC4589490.
      Citations: 167     Fields:    Translation:HumansAnimalsCells
    57. Krakowiak P, Walker CK, Tancredi DJ, Hertz-Picciotto I. Maternal Recall Versus Medical Records of Metabolic Conditions from the Prenatal Period: A Validation Study. Matern Child Health J. 2015 Sep; 19(9):1925-35. PMID: 25656730; PMCID: PMC4522222.
      Citations: 15     Fields:    Translation:Humans
    58. Jing J, He L, Sun A, Quintana A, Ding Y, Ma G, Tan P, Liang X, Zheng X, Chen L, Shi X, Zhang SL, Zhong L, Huang Y, Dong MQ, Walker CL, Hogan PG, Wang Y, Zhou Y. Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca?? influx. Nat Cell Biol. 2015 Oct; 17(10):1339-47. PMID: 26322679; PMCID: PMC4589512.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    59. Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel RA, Gray KA, Ha EH, Junien C, Karagas M, Kawamoto T, Paige Lawrence B, Perera FP, Prins GS, Puga A, Rosenfeld CS, Sherr DH, Sly PD, Suk W, Sun Q, Toppari J, van den Hazel P, Walker CL, Heindel JJ. Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives. Endocrinology. 2015 Oct; 156(10):3408-15. PMID: 26241067; PMCID: PMC4588822.
      Citations: 71     Fields:    Translation:HumansCellsPHPublic Health
    60. Wang Q, Walker CL, Trevi?o LS. Phosphorylation of epigenetic "readers, writers and erasers": Implications for developmental reprogramming and the epigenetic basis for health and disease. Prog Biophys Mol Biol. 2015 Jul; 118(1-2):8-13. PMID: 25841987; PMCID: PMC4580755.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    61. Sahin K, Cross B, Sahin N, Ciccone K, Suleiman S, Osunkoya AO, Master V, Harris W, Carthon B, Mohammad R, Bilir B, Wertz K, Moreno CS, Walker CL, Kucuk O. Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model. Arch Biochem Biophys. 2015 Apr 15; 572:36-39. PMID: 25602702; PMCID: PMC5657428.
      Citations: 4     Fields:    Translation:Animals
    62. Wong RL, Wang Q, Bosland MC, Chen J, Medvedovic M, Prins GS, Kannan K, Ho SM, Walker CL, Trevi?o LS. Identification of secretaglobin Scgb2a1 as a target for developmental reprogramming by BPA in the rat prostate. Epigenetics. 2015; 10(2):127-34. PMID: 25612011; PMCID: PMC4623267.
      Citations: 27     Fields:    Translation:AnimalsCells
    63. Wang Q, Walker CL, Trevi?o LS. Hypothesis: Activation of rapid signaling by environmental estrogens and epigenetic reprogramming in breast cancer. Reprod Toxicol. 2015 Jul; 54:136-40. PMID: 25554384; PMCID: PMC4563990.
      Citations: 16     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    64. Dere R, Perkins AL, Bawa-Khalfe T, Jonasch D, Walker CL. ?-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma. J Am Soc Nephrol. 2015 Mar; 26(3):553-64. PMID: 25313256; PMCID: PMC4341469.
      Citations: 37     Fields:    Translation:HumansCells
    65. Stossi F, Bolt MJ, Ashcroft FJ, Lamerdin JE, Melnick JS, Powell RT, Dandekar RD, Mancini MG, Walker CL, Westwick JK, Mancini MA. Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays. Chem Biol. 2014 Jun 19; 21(6):743-53. PMID: 24856822; PMCID: PMC4301571.
      Citations: 26     Fields:    Translation:HumansCells
    66. Chen XW, Saltiel AR, Walker CL, Martin TD, Kaplan RE, Reiner DJ, Der CJ. Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion. Mol Cell. 2014 Jan 23; 53(2):209-20. PMID: 24389102; PMCID: PMC3955741.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    67. Prins GS, Hu WY, Shi GB, Hu DP, Majumdar S, Li G, Huang K, Nelles JL, Ho SM, Walker CL, Kajdacsy-Balla A, van Breemen RB. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology. 2014 Mar; 155(3):805-17. PMID: 24424067; PMCID: PMC3929731.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    68. Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nat Cell Biol. 2013 Oct; 15(10):1186-96. PMID: 23955302; PMCID: PMC3789865.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    69. Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):E2950-7. PMID: 23878245; PMCID: PMC3740898.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    70. Wong RL, Walker CL. Molecular pathways: environmental estrogens activate nongenomic signaling to developmentally reprogram the epigenome. Clin Cancer Res. 2013 Jul 15; 19(14):3732-7. PMID: 23549878; PMCID: PMC3879948.
      Citations: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    71. Schroeder DI, Blair JD, Lott P, Yu HO, Hong D, Crary F, Ashwood P, Walker C, Korf I, Robinson WP, LaSalle JM. The human placenta methylome. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6037-42. PMID: 23530188; PMCID: PMC3625261.
      Citations: 139     Fields:    Translation:HumansCells
    72. Walker CL, Ho SM. Developmental reprogramming of cancer susceptibility. Nat Rev Cancer. 2012 Jun 14; 12(7):479-86. PMID: 22695395; PMCID: PMC3820510.
      Citations: 68     Fields:    Translation:Humans
    73. Koenig CM, Walker CK, Qi L, Pessah IN, Berman RF. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice. PLoS One. 2012; 7(6):e38911. PMID: 22719983; PMCID: PMC3374803.
      Citations: 1     Fields:    Translation:AnimalsPHPublic Health
    74. Jonasch E, Futreal PA, Davis IJ, Bailey ST, Kim WY, Brugarolas J, Giaccia AJ, Kurban G, Pause A, Frydman J, Zurita AJ, Rini BI, Sharma P, Atkins MB, Walker CL, Rathmell WK. State of the science: an update on renal cell carcinoma. Mol Cancer Res. 2012 Jul; 10(7):859-80. PMID: 22638109; PMCID: PMC3399969.
      Citations: 78     Fields:    Translation:HumansCells
    75. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bourquin JP, Boya P, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490; PMCID: PMC3404883.
      Citations: 1751     Fields:    Translation:HumansAnimals
    76. Greathouse KL, Bredfeldt T, Everitt JI, Lin K, Berry T, Kannan K, Mittelstadt ML, Ho SM, Walker CL. Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. Mol Cancer Res. 2012 Apr; 10(4):546-57. PMID: 22504913; PMCID: PMC3879949.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    77. Kim J, Otto N, Conti CJ, Gimenz-Conti IB, Walker CL. Immunohistochemical analysis of mTOR activity in tissues. Methods Mol Biol. 2012; 821:215-25. PMID: 22125067.
      Citations: 2     Fields:    Translation:HumansAnimals
    78. Walker CK, Sweet RL. Gonorrhea infection in women: prevalence, effects, screening, and management. Int J Womens Health. 2011; 3:197-206. PMID: 21845064; PMCID: PMC3150204.
      Citations: 27     
    79. Itamochi H, Yoshida T, Walker CL, Bartholomeusz C, Aoki D, Ishihara H, Suzuki N, Kigawa J, Terakawa N, Ueno NT. Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: cytoplasmic sequestration of CDK2 by p27. Gynecol Oncol. 2011 Sep; 122(3):641-7. PMID: 21652059.
      Citations: 12     Fields:    Translation:HumansCells
    80. Walker CL. Epigenomic reprogramming of the developing reproductive tract and disease susceptibility in adulthood. Birth Defects Res A Clin Mol Teratol. 2011 Aug; 91(8):666-71. PMID: 21656660; PMCID: PMC4266586.
      Citations: 11     Fields:    Translation:HumansAnimals
    81. Alexander A, Walker CL. The role of LKB1 and AMPK in cellular responses to stress and damage. FEBS Lett. 2011 Apr 06; 585(7):952-7. PMID: 21396365.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    82. Alexander A, Walker CL. Differential localization of ATM is correlated with activation of distinct downstream signaling pathways. Cell Cycle. 2010 Sep 15; 9(18):3685-6. PMID: 20890104; PMCID: PMC3030254.
      Citations: 34     Fields:    Translation:HumansCells
    83. Slomovitz BM, Lu KH, Johnston T, Coleman RL, Munsell M, Broaddus RR, Walker C, Ramondetta LM, Burke TW, Gershenson DM, Wolf J. A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma. Cancer. 2010 Dec 01; 116(23):5415-9. PMID: 20681032; PMCID: PMC5120730.
      Citations: 81     Fields:    Translation:HumansCTClinical Trials
    84. McCampbell AS, Broaddus RR, Walker CL. Loss of inhibitory insulin receptor substrate-1 phosphorylation: An early event in endometrial hyperplasia and progression to carcinoma. Cell Cycle. 2010 Jul 15; 9(14):2698-9. PMID: 20676044.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    85. Alexander A, Kim J, Walker CL. ATM engages the TSC2/mTORC1 signaling node to regulate autophagy. Autophagy. 2010 Jul; 6(5):672-3. PMID: 20581436; PMCID: PMC3259740.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    86. Short JD, Dere R, Houston KD, Cai SL, Kim J, Bergeron JM, Shen J, Liang J, Bedford MT, Mills GB, Walker CL. AMPK-mediated phosphorylation of murine p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stability. Mol Carcinog. 2010 May; 49(5):429-39. PMID: 20146253; PMCID: PMC3818129.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    87. Bredfeldt TG, Greathouse KL, Safe SH, Hung MC, Bedford MT, Walker CL. Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT. Mol Endocrinol. 2010 May; 24(5):993-1006. PMID: 20351197; PMCID: PMC2870935.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    88. Darling TN, Pacheco-Rodriguez G, Gorio A, Lesma E, Walker C, Moss J. Lymphangioleiomyomatosis and TSC2-/- cells. Lymphat Res Biol. 2010 Mar; 8(1):59-69. PMID: 20235888; PMCID: PMC2883471.
      Citations: 15     Fields:    Translation:HumansAnimals
    89. McCampbell AS, Harris HA, Crabtree JS, Winneker RC, Walker CL, Broaddus RR. Loss of inhibitory insulin receptor substrate-1 phosphorylation is an early event in mammalian target of rapamycin-dependent endometrial hyperplasia and carcinoma. Cancer Prev Res (Phila). 2010 Mar; 3(3):290-300. PMID: 20179297; PMCID: PMC4103009.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    90. Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4153-8. PMID: 20160076; PMCID: PMC2840158.
      Citations: 319     Fields:    Translation:HumansAnimalsCells
    91. Dere R, Wilson PD, Sandford RN, Walker CL. Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR. PLoS One. 2010 Feb 16; 5(2):e9239. PMID: 20169078; PMCID: PMC2821926.
      Citations: 43     Fields:    Translation:HumansCells
    92. Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environ Health Perspect. 2010 Jan; 118(1):161-6. PMID: 20056569; PMCID: PMC2831962.
      Citations: 34     Fields:    Translation:HumansAnimalsPHPublic Health
    93. Crabtree JS, Jelinsky SA, Harris HA, Choe SE, Cotreau MM, Kimberland ML, Wilson E, Saraf KA, Liu W, McCampbell AS, Dave B, Broaddus RR, Brown EL, Kao W, Skotnicki JS, Abou-Gharbia M, Winneker RC, Walker CL. Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway. Cancer Res. 2009 Aug 01; 69(15):6171-8. PMID: 19622772.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    94. Blando J, Portis M, Benavides F, Alexander A, Mills G, Dave B, Conti CJ, Kim J, Walker CL. PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth. Am J Pathol. 2009 May; 174(5):1869-79. PMID: 19395652; PMCID: PMC2671275.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    95. Hassan M, Zhang D, Salama S, Hamada F, Arafa H, Fouad H, Walker C, Al-Hendy A. Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model. Gynecol Obstet Invest. 2009; 68(1):19-32. PMID: 19325244; PMCID: PMC4677717.
      Citations:    
    96. Yu JJ, Robb VA, Morrison TA, Ariazi EA, Karbowniczek M, Astrinidis A, Wang C, Hernandez-Cuebas L, Seeholzer LF, Nicolas E, Hensley H, Jordan VC, Walker CL, Henske EP. Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2635-40. PMID: 19202070; PMCID: PMC2637277.
      Citations: 85     Fields:    Translation:Animals
    97. Kim J, Jonasch E, Alexander A, Short JD, Cai S, Wen S, Tsavachidou D, Tamboli P, Czerniak BA, Do KA, Wu KJ, Marlow LA, Wood CG, Copland JA, Walker CL. Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma. Clin Cancer Res. 2009 Jan 01; 15(1):81-90. PMID: 19118035; PMCID: PMC3030253.
      Citations: 31     Fields:    Translation:HumansCells
    98. Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ. Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril. 2008 Oct; 90(4):911-40. PMID: 18929049; PMCID: PMC4086418.
      Citations: 115     Fields:    Translation:Humans
    99. Short JD, Houston KD, Dere R, Cai SL, Kim J, Johnson CL, Broaddus RR, Shen J, Miyamoto S, Tamanoi F, Kwiatkowski D, Mills GB, Walker CL. AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27. Cancer Res. 2008 Aug 15; 68(16):6496-506. PMID: 18701472; PMCID: PMC3011867.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    100. Lu KH, Wu W, Dave B, Slomovitz BM, Burke TW, Munsell MF, Broaddus RR, Walker CL. Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2543-50. PMID: 18451215.
      Citations: 29     Fields:    Translation:HumansCells
    101. McCampbell AS, Walker CL, Broaddus RR, Cook JD, Davies PJ. Developmental reprogramming of IGF signaling and susceptibility to endometrial hyperplasia in the rat. Lab Invest. 2008 Jun; 88(6):615-26. PMID: 18427555.
      Citations: 15     Fields:    Translation:AnimalsCells
    102. Wei C, Amos CI, Zhang N, Wang X, Rashid A, Walker CL, Behringer RR, Frazier ML. Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling. Clin Cancer Res. 2008 Feb 15; 14(4):1167-71. PMID: 18281551.
      Citations: 29     Fields:    Translation:AnimalsCells
    103. Woodruff TK, Walker CL. Fetal and early postnatal environmental exposures and reproductive health effects in the female. Fertil Steril. 2008 Feb; 89(2 Suppl):e47-51. PMID: 18308062; PMCID: PMC2527475.
      Citations: 13     Fields:    Translation:HumansAnimalsPHPublic Health
    104. Isobe A, Takeda T, Sakata M, Miyake A, Yamamoto T, Minekawa R, Nishimoto F, Oskamoto Y, Walker CL, Kimura T. Dual repressive effect of angiotensin II-type 1 receptor blocker telmisartan on angiotensin II-induced and estradiol-induced uterine leiomyoma cell proliferation. Hum Reprod. 2008 Feb; 23(2):440-6. PMID: 17993476.
      Citations: 17     Fields:    Translation:AnimalsCells
    105. Laping NJ, Everitt JI, Frazier KS, Burgert M, Portis MJ, Cadacio C, Gold LI, Walker CL. Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats. Clin Cancer Res. 2007 May 15; 13(10):3087-99. PMID: 17505012.
      Citations: 27     Fields:    Translation:AnimalsCells
    106. Hall WC, Elder B, Walker CL, Cai SL, Peters DG, Goodman DG, Ulland BM, Borzelleca JF. Spontaneous renal tubular hyperplastic and neoplastic lesions in three Sprague-Dawley rats from a 90-day toxicity study. Toxicol Pathol. 2007 Feb; 35(2):233-41. PMID: 17366317.
      Citations: 2     Fields:    Translation:Animals
    107. Cook JD, Davis BJ, Goewey JA, Berry TD, Walker CL. Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats. Reprod Sci. 2007 Feb; 14(2):121-36. PMID: 17636224.
      Citations: 24     Fields:    Translation:Animals
    108. Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, Larrea M, Kondo S, Dumont DJ, Gutterman JU, Walker CL, Slingerland JM, Mills GB. The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol. 2007 Feb; 9(2):218-24. PMID: 17237771.
      Citations: 408     Fields:    Translation:HumansCells
    109. Walker CL, Everitt JI, Dekant W, Vamvakas S, Mally A. Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro. Toxicology. 2006 Jul 05; 224(1-2):108-18. PMID: 16730402.
      Citations: 7     Fields:    Translation:Animals
    110. Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, Shen J, Guo R, Johnson CL, Kiguchi K, Walker CL. Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning. J Cell Biol. 2006 Apr 24; 173(2):279-89. PMID: 16636147; PMCID: PMC2063818.
      Citations: 163     Fields:    Translation:HumansCells
    111. Cai SL, Walker CL. TSC2, a key player in tumor suppression and cystic kidney disease. Nephrol Ther. 2006 Jan; 2 Suppl 2:S119-22. PMID: 17373211.
      Citations: 2     Fields:    Translation:HumansCells
    112. Walker CL, Stewart EA. Uterine fibroids: the elephant in the room. Science. 2005 Jun 10; 308(5728):1589-92. PMID: 15947177.
      Citations: 185     Fields:    Translation:HumansAnimalsCells
    113. Cook JD, Davis BJ, Cai SL, Barrett JC, Conti CJ, Walker CL. Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8644-9. PMID: 15937110; PMCID: PMC1150843.
      Citations: 48     Fields:    Translation:Animals
    114. Cook JD, Walker CL. Treatment strategies for uterine leiomyoma: the role of hormonal modulation. Semin Reprod Med. 2004 May; 22(2):105-11. PMID: 15164305.
      Citations: 14     Fields:    Translation:Humans
    115. Walker CL, Hunter D, Everitt JI. Uterine leiomyoma in the Eker rat: a unique model for important diseases of women. Genes Chromosomes Cancer. 2003 Dec; 38(4):349-56. PMID: 14566855.
      Citations: 30     Fields:    Translation:HumansAnimals
    116. Kleymenova E, Everitt JI, Pluta L, Portis M, Gnarra JR, Walker CL. Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice. Carcinogenesis. 2004 Mar; 25(3):309-15. PMID: 14604887.
      Citations: 29     Fields:    Translation:Animals
    117. Burke TW, Walker CL. Arzoxifene as therapy for endometrial cancer. Gynecol Oncol. 2003 Aug; 90(2 Pt 2):S40-6. PMID: 12928005.
      Citations: 7     Fields:    Translation:Humans
    118. Liu MY, Poellinger L, Walker CL. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene. Cancer Res. 2003 May 15; 63(10):2675-80. PMID: 12750296.
      Citations: 22     Fields:    Translation:AnimalsCells
    119. Houston KD, Copland JA, Broaddus RR, Gottardis MM, Fischer SM, Walker CL. Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. Cancer Res. 2003 Mar 15; 63(6):1221-7. PMID: 12649180.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    120. Hodges LC, Cook JD, Lobenhofer EK, Li L, Bennett L, Bushel PR, Aldaz CM, Afshari CA, Walker CL. Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells. Mol Cancer Res. 2003 Feb; 1(4):300-11. PMID: 12612058.
      Citations: 42     Fields:    Translation:HumansCells
    121. Cai S, Everitt JI, Kugo H, Cook J, Kleymenova E, Walker CL. Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development. Am J Pathol. 2003 Feb; 162(2):457-68. PMID: 12547704; PMCID: PMC1851170.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    122. Cesen-Cummings K, Houston KD, Copland JA, Moorman VJ, Walker CL, Davis BJ. Uterine leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone signaling. J Soc Gynecol Investig. 2003 Jan; 10(1):11-20. PMID: 12517588.
      Citations: 10     Fields:    Translation:AnimalsCells
    123. Astrinidis A, Cash TP, Hunter DS, Walker CL, Chernoff J, Henske EP. Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene. 2002 Dec 05; 21(55):8470-6. PMID: 12466966.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    124. Keshavarzi A, Vaezy S, Noble ML, Chi EY, Walker C, Martin RW, Fujimoto VY. Treatment of uterine leiomyosarcoma in a xenograft nude mouse model using high-intensity focused ultrasound: a potential treatment modality for recurrent pelvic disease. Gynecol Oncol. 2002 Sep; 86(3):344-50. PMID: 12217758.
      Citations: 4     Fields:    Translation:Animals
    125. Yoon HS, Monks TJ, Everitt JI, Walker CL, Lau SS. Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity. Am J Physiol Renal Physiol. 2002 Aug; 283(2):F262-70. PMID: 12110509.
      Citations: 6     Fields:    Translation:Animals
    126. Hunter DS, Kugoh H, Cai SL, Mullen JP, Manfioletti G, Fuhrman U, Walker CL, Klotzb?cher M. Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function. Cancer Res. 2002 Jul 01; 62(13):3766-72. PMID: 12097287.
      Citations: 14     Fields:    Translation:AnimalsCells
    127. Irani C, Goncharova EA, Hunter DS, Walker CL, Panettieri RA, Krymskaya VP. Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration. Am J Physiol Lung Cell Mol Physiol. 2002 Apr; 282(4):L854-62. PMID: 11880313.
      Citations: 16     Fields:    Translation:AnimalsCells
    128. Kugoh H, Kleymenova E, Walker CL. Retention of membrane-localized beta-catenin in cells lacking functional polycystin-1 and tuberin. Mol Carcinog. 2002 Mar; 33(3):131-6. PMID: 11870878.
      Citations: 8     Fields:    Translation:AnimalsCells
    129. Walker CL. Role of hormonal and reproductive factors in the etiology and treatment of uterine leiomyoma. Recent Prog Horm Res. 2002; 57:277-94. PMID: 12017548.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
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