Histone-Lysine N-Methyltransferase
"Histone-Lysine N-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. EC 2.1.1.43.
| Descriptor ID |
D011495
|
| MeSH Number(s) |
D08.811.913.555.500.800.400
|
| Concept/Terms |
Histone-Lysine N-Methyltransferase- Histone-Lysine N-Methyltransferase
- Histone Lysine N Methyltransferase
- N-Methyltransferase, Histone-Lysine
- Protein Methylase III
- Histone-Lysine Methyltransferase
- Histone Lysine Methyltransferase
- Methyltransferase, Histone-Lysine
- Protein Lysine Methyltransferase
- Methyltransferase, Protein Lysine
- Protein Methyltransferase III
|
Below are MeSH descriptors whose meaning is more general than "Histone-Lysine N-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Histone-Lysine N-Methyltransferase".
This graph shows the total number of publications written about "Histone-Lysine N-Methyltransferase" by people in this website by year, and whether "Histone-Lysine N-Methyltransferase" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 9 | 9 |
| 2006 | 2 | 2 | 4 |
| 2007 | 4 | 4 | 8 |
| 2008 | 4 | 7 | 11 |
| 2009 | 3 | 6 | 9 |
| 2010 | 4 | 14 | 18 |
| 2011 | 4 | 6 | 10 |
| 2012 | 4 | 10 | 14 |
| 2013 | 2 | 9 | 11 |
| 2014 | 7 | 13 | 20 |
| 2015 | 3 | 7 | 10 |
| 2016 | 10 | 8 | 18 |
| 2017 | 3 | 3 | 6 |
| 2018 | 9 | 3 | 12 |
| 2019 | 6 | 3 | 9 |
| 2020 | 7 | 3 | 10 |
| 2021 | 9 | 2 | 11 |
| 2022 | 1 | 4 | 5 |
| 2023 | 2 | 1 | 3 |
| 2024 | 6 | 3 | 9 |
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Below are the most recent publications written about "Histone-Lysine N-Methyltransferase" by people in Profiles.
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MLL oncoprotein levels influence leukemia lineage identities. Nat Commun. 2024 Oct 29; 15(1):9341.
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Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia. Commun Biol. 2024 Oct 04; 7(1):1257.
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Perturbing TET2 condensation promotes aberrant genome-wide DNA methylation and curtails leukaemia cell growth. Nat Cell Biol. 2024 Dec; 26(12):2154-2167.
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Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder. Life Sci Alliance. 2024 Nov; 7(11).
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SMYD5 is a regulator of the mild hypothermia response. Cell Rep. 2024 Aug 27; 43(8):114554.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature. 2024 Aug; 632(8025):656-663.
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Comprehensive EHMT1 variants analysis broadens genotype-phenotype associations and molecular mechanisms in Kleefstra syndrome. Am J Hum Genet. 2024 Aug 08; 111(8):1605-1625.
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Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation. J Biol Chem. 2024 Aug; 300(8):107527.
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Palbociclib and chemotherapy followed by blinatumomab consolidation to CAR-T cell therapy in KMT2A-rearranged, therapy-related acute lymphoblastic leukemia. Pediatr Blood Cancer. 2024 Jun; 71(6):e30964.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.