Protein Methyltransferases
"Protein Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the methylation of amino acids after their incorporation into a polypeptide chain. S-Adenosyl-L-methionine acts as the methylating agent. EC 2.1.1.
| Descriptor ID |
D011496
|
| MeSH Number(s) |
D08.811.913.555.500.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Protein Methyltransferases".
This graph shows the total number of publications written about "Protein Methyltransferases" by people in this website by year, and whether "Protein Methyltransferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Methyltransferases" by people in Profiles.
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Integrative Molecular Characterization of Malignant Pleural Mesothelioma. Cancer Discov. 2018 12; 8(12):1548-1565.
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Lysine methylation: beyond histones. Acta Biochim Biophys Sin (Shanghai). 2012 Jan; 44(1):14-27.
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Crosstalk between Arg?1175 methylation and Tyr?1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat Cell Biol. 2011 Feb; 13(2):174-81.
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Lysine methylation of the NF-?B subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-?B signaling. Nat Immunol. 2011 Jan; 12(1):29-36.
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PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Res. 2010 Sep; 20(9):1023-33.
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KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells. 2010 Feb; 28(2):201-12.
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CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell. 2008 Dec 05; 32(5):718-26.
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The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet. 2008 Sep 12; 4(9):e1000190.
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A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev. 2008 Aug 01; 22(15):2048-61.
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Esco2 is a novel corepressor that associates with various chromatin modifying enzymes. Biochem Biophys Res Commun. 2008 Jul 25; 372(2):298-304.