Catechol O-Methyltransferase
"Catechol O-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine.
Descriptor ID |
D002394
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MeSH Number(s) |
D08.811.913.555.500.250
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Concept/Terms |
Catechol O-Methyltransferase- Catechol O-Methyltransferase
- O-Methyltransferase, Catechol
- Catechol-O-Methyltransferase
- Catechol O Methyltransferase
- Catechol Methyltransferase
- Methyltransferase, Catechol
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Below are MeSH descriptors whose meaning is more general than "Catechol O-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Catechol O-Methyltransferase".
This graph shows the total number of publications written about "Catechol O-Methyltransferase" by people in this website by year, and whether "Catechol O-Methyltransferase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 2 | 0 | 2 |
2008 | 1 | 0 | 1 |
2010 | 1 | 2 | 3 |
2011 | 0 | 1 | 1 |
2012 | 3 | 0 | 3 |
2013 | 3 | 1 | 4 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Catechol O-Methyltransferase" by people in Profiles.
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Cognitive impairment in patients with melanoma before adjuvant immune checkpoint inhibitor therapy and associations with brain gray matter, catechol-O-methyltransferase genotype, and psychological factors. Cancer. 2025 Jan 15; 131(2):e35683.
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Effectiveness of a social problem solving training in youth in detention or on probation: An RCT and pre-post community implementation. Int J Law Psychiatry. 2020 Sep - Oct; 72:101626.
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Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity. Am J Addict. 2017 Jan; 26(1):42-49.
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Association of catechol-O-methyltransferase Val(108/158) Met genetic polymorphism with schizophrenia, P50 sensory gating, and negative symptoms in a Chinese population. Psychiatry Res. 2016 Aug 30; 242:271-276.
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Sex-dichotomous effects of functional COMT genetic variations on cognitive functions disappear after menopause in both health and schizophrenia. Eur Neuropsychopharmacol. 2015 Dec; 25(12):2349-63.
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Variations in opioid receptor genes in neonatal abstinence syndrome. Drug Alcohol Depend. 2015 Oct 01; 155:253-9.
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Genetic predictor of working memory and prefrontal function in women with HIV. J Neurovirol. 2015 Feb; 21(1):81-91.
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COMT Genetic Reduction Produces Sexually Divergent Effects on Cortical Anatomy and Working Memory in Mice and Humans. Cereb Cortex. 2015 Sep; 25(9):2529-41.
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Implications of COMT long-range interactions on the phenotypic variability of 22q11.2 deletion syndrome. Nucleus. 2013 Nov-Dec; 4(6):487-93.
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Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer. Anesthesiology. 2013 Dec; 119(6):1422-33.