Guanidinoacetate N-Methyltransferase
"Guanidinoacetate N-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This enzyme catalyzes the last step of CREATINE biosynthesis by catalyzing the METHYLATION of guanidinoacetate to CREATINE.
| Descriptor ID |
D050937
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| MeSH Number(s) |
D08.811.913.555.500.425
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| Concept/Terms |
Guanidinoacetate N-Methyltransferase- Guanidinoacetate N-Methyltransferase
- Guanidinoacetate N Methyltransferase
- N-Methyltransferase, Guanidinoacetate
- Guanidinoacetate Methylpherase
- Methylpherase, Guanidinoacetate
- Methionine-Guanidinoacetic Transmethylase
- Methionine Guanidinoacetic Transmethylase
- Transmethylase, Methionine-Guanidinoacetic
- Guanidinoacetate Transmethylase
- Transmethylase, Guanidinoacetate
- Guanidoacetate Methyltransferase
- Methyltransferase, Guanidoacetate
- GA Methyltransferase
- Methyltransferase, GA
- Guanidinoacetate Methyltransferase
- Methyltransferase, Guanidinoacetate
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Below are MeSH descriptors whose meaning is more general than "Guanidinoacetate N-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Guanidinoacetate N-Methyltransferase".
This graph shows the total number of publications written about "Guanidinoacetate N-Methyltransferase" by people in this website by year, and whether "Guanidinoacetate N-Methyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Guanidinoacetate N-Methyltransferase" by people in Profiles.
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Laboratory Diagnosis of Cerebral Creatine Deficiency Syndromes by Determining Creatine and Guanidinoacetate in Plasma and Urine. Methods Mol Biol. 2022; 2546:129-140.
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Guanidinoacetate methyltransferase (GAMT) deficiency: outcomes in 48 individuals and recommendations for diagnosis, treatment and monitoring. Mol Genet Metab. 2014 Jan; 111(1):16-25.
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Synthesis of guanidinoacetate and creatine from amino acids by rat pancreas. Br J Nutr. 2014 Feb; 111(4):571-7.
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Biochemical, molecular, and clinical diagnoses of patients with cerebral creatine deficiency syndromes. Mol Genet Metab. 2013 Jul; 109(3):260-8.
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Diagnosis of creatine metabolism disorders by determining creatine and guanidinoacetate in plasma and urine. Methods Mol Biol. 2010; 603:175-85.
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Expanded clinical and molecular spectrum of guanidinoacetate methyltransferase (GAMT) deficiency. Mol Genet Metab. 2009 Jan; 96(1):38-43.
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Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo. Am J Physiol Endocrinol Metab. 2009 Feb; 296(2):E256-61.
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Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo. Am J Physiol Renal Physiol. 2007 Dec; 293(6):F1799-804.
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Methyl balance and transmethylation fluxes in humans. Am J Clin Nutr. 2007 Jan; 85(1):19-25.
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Novel genomic loci influencing plasma homocysteine levels. Stroke. 2006 Jul; 37(7):1703-9.