"Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
| Descriptor ID |
D008780
|
| MeSH Number(s) |
D08.811.913.555.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Methyltransferases".
This graph shows the total number of publications written about "Methyltransferases" by people in this website by year, and whether "Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 1 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 3 | 3 | 6 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 1 | 3 |
| 2023 | 1 | 3 | 4 |
| 2024 | 1 | 3 | 4 |
| 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Methyltransferases" by people in Profiles.
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Synthesis, Structure-Activity Relationships, and Antitumor Activities of Quinoxiline-Containing Inhibitors of the Protein-Protein Interactions between Transcription Coactivator AF9/ENL and DOT1L/AF4. J Med Chem. 2025 Sep 25; 68(18):19396-19414.
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Clinical impact of pharmacogenetic risk variants in a large chinese cohort. Nat Commun. 2025 Jul 09; 16(1):6344.
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RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS. Nat Commun. 2025 Feb 17; 16(1):1703.
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The effect of m6A methyltransferase METTL3 mediated TMEM30A regulation on tumor energy metabolism and cisplatin anti-tumor activity in oral squamous cell carcinoma. Life Sci. 2024 Dec 01; 358:123122.
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Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis. Acta Neuropathol Commun. 2024 08 28; 12(1):138.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature. 2024 Aug; 632(8025):656-663.
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SETD3 is a mechanosensitive enzyme that methylates actin on His73 to regulate mitochondrial dynamics and function. J Cell Sci. 2024 07 15; 137(14).
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Insights into E. coli Cyclopropane Fatty Acid Synthase (CFAS) Towards Enantioselective Carbene Free Biocatalytic Cyclopropanation. Angew Chem Int Ed Engl. 2024 07 15; 63(29):e202403493.
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One form and two functions: MBD of SETDB2 is a protein-interacting domain. Structure. 2024 03 07; 32(3):258-260.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.