"Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
Descriptor ID |
D008780
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MeSH Number(s) |
D08.811.913.555.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Methyltransferases".
This graph shows the total number of publications written about "Methyltransferases" by people in this website by year, and whether "Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
1997 | 1 | 0 | 1 |
1998 | 3 | 0 | 3 |
1999 | 1 | 0 | 1 |
2001 | 2 | 1 | 3 |
2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2005 | 3 | 3 | 6 |
2006 | 3 | 1 | 4 |
2007 | 2 | 2 | 4 |
2008 | 3 | 2 | 5 |
2010 | 6 | 1 | 7 |
2011 | 4 | 3 | 7 |
2012 | 2 | 2 | 4 |
2013 | 2 | 1 | 3 |
2014 | 3 | 0 | 3 |
2015 | 3 | 0 | 3 |
2016 | 3 | 3 | 6 |
2017 | 3 | 1 | 4 |
2018 | 4 | 2 | 6 |
2019 | 4 | 0 | 4 |
2020 | 3 | 2 | 5 |
2021 | 3 | 2 | 5 |
2022 | 2 | 4 | 6 |
2023 | 1 | 2 | 3 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methyltransferases" by people in Profiles.
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One form and two functions: MBD of SETDB2 is a protein-interacting domain. Structure. 2024 Mar 07; 32(3):258-260.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.
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Roving methyltransferases generate a mosaic epigenetic landscape and influence evolution in Bacteroides fragilis group. Nat Commun. 2023 07 10; 14(1):4082.
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Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase. ACS Chem Biol. 2023 04 21; 18(4):734-745.
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Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. J Med Chem. 2023 01 12; 66(1):934-950.
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Triple combination targeting methyltransferase, BCL-2, and PD-1 facilitates antileukemia responses in acute myeloid leukemia. Cancer. 2023 02 15; 129(4):531-540.
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GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism. Redox Biol. 2022 10; 56:102458.
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Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells. Int J Biol Sci. 2022; 18(8):3337-3357.
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Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition. Cancer Cell. 2022 05 09; 40(5):439-440.
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Enzymatic characterization of mRNA cap adenosine-N6 methyltransferase PCIF1 activity on uncapped RNAs. J Biol Chem. 2022 04; 298(4):101751.