DNA (Cytosine-5-)-Methyltransferases
"DNA (Cytosine-5-)-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.
| Descriptor ID |
D004248
|
| MeSH Number(s) |
D08.811.913.555.500.350.100.500
|
| Concept/Terms |
DNA (Cytosine-5-)-Methyltransferases- DNA (Cytosine-5-)-Methyltransferases
- DNA (Cytosine-5-)-Methyltransferase
- DNA Cytosine-5-Methylase
- Cytosine-5-Methylase, DNA
- DNA Cytosine 5 Methylase
- DNA (Cytosine 5) Methyltransferase
|
Below are MeSH descriptors whose meaning is more general than "DNA (Cytosine-5-)-Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "DNA (Cytosine-5-)-Methyltransferases".
This graph shows the total number of publications written about "DNA (Cytosine-5-)-Methyltransferases" by people in this website by year, and whether "DNA (Cytosine-5-)-Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 3 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2013 | 5 | 1 | 6 |
| 2014 | 2 | 2 | 4 |
| 2015 | 4 | 2 | 6 |
| 2016 | 4 | 0 | 4 |
| 2017 | 5 | 1 | 6 |
| 2018 | 3 | 3 | 6 |
| 2019 | 1 | 4 | 5 |
| 2020 | 7 | 1 | 8 |
| 2021 | 1 | 0 | 1 |
| 2022 | 4 | 1 | 5 |
| 2023 | 1 | 1 | 2 |
| 2024 | 3 | 2 | 5 |
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Below are the most recent publications written about "DNA (Cytosine-5-)-Methyltransferases" by people in Profiles.
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Recurrent carotid paragangliomas in a syndromic patient with a heterozygous missense variant in DNA Methyltransferase 3 Alpha. Am J Med Genet A. 2025 Jan; 197(1):e63849.
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TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25; 187(15):4030-4042.e13.
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Loss of Dnmt3a increases self-renewal and resistance to pegIFN-a in JAK2-V617F-positive myeloproliferative neoplasms. Blood. 2024 06 13; 143(24):2490-2503.
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Dose-dependent effects of Dnmt3a in an inducible murine model of KrasG12D-driven leukemia. Exp Hematol. 2024 Jul; 135:104248.
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Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1. JAMA Cardiol. 2024 Jun 01; 9(6):497-506.
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Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms After Autologous Transplant for Hodgkin Lymphoma. J Clin Oncol. 2024 Jul 10; 42(20):2415-2424.
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EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential. Blood Adv. 2023 04 11; 7(7):1308-1311.
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DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 04; 25(4):528-539.
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Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases. Curr Opin Struct Biol. 2022 08; 75:102433.
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First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation. J Med Chem. 2022 08 11; 65(15):10554-10566.