(Katherine King, Hugo Bellen, Richard Gibbs)Aug 1, 2023 - Jul 31, 2027 Chan Zuckerberg Institute Identifying the Genetic Basis of Rare Disease in Children Role Description: The goal of this study is to perform whole genome sequencing of children with rare disease and their parents to identify rare disease gene variants and study their function in cell and animal models. The long term goal is to diagnose and treat disease in humans. Role: Co-Principal Investigator |
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5P01CA265748 (Goodell, Margaret)Apr 1, 2022 - Mar 31, 2027 NIH Modifiable Drivers of Expansion and Malignant Transformation from Clonal Hematopoiesis Role Description: The overall goal of this Program, with three interactive Projects and two Cores, is to identify modifiable risk factors of CH-associated HSPC expansion and subsequent malignant transformation, with a long-term view toward developing cancer prevention strategies. Role: Project 1 Lead, Administrative Core Co-Lead |
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R35HL155672 (KING, KATHERINE YUDEH)Jul 1, 2021 - Jun 30, 2028 NIH Impact of Infection and Inflammation on Primitive Hematopoiesis Role: Principal Investigator |
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T32GM136611 (KING, KATHERINE YUDEH)Jul 1, 2020 - Jun 30, 2030 NIH Medical Scientist Training Program Role: Principal Investigator |
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(Margaret Goodell)Jul 1, 2019 - Jun 30, 2022 Helis Medical Research Foundation Environmental Drivers of Clonal Hematopoiesis Role: Co-PI |
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R01AI141716 (BALDRIDGE, MEGAN T)Nov 7, 2018 - Oct 31, 2023 NIH Microbiota-dependent regulation of primitive hematopoieses Role Description: The goal of this study is to quantify the impact of a variety of environmental stressors on clonal dynamics of a panel of genetically distinct hematopoietic stem cell clones. Role: Co-PI |
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R01HL134880 (KING, KATHERINE YUDEH)Aug 1, 2017 - Jun 30, 2021 NIH Inflammatory Regulation of Hematopoietic Stem and Progenitor Cells to Enhance Innate Immunity Role: Principal Investigator |
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R01HL136333 (KING, KATHERINE YUDEH)May 1, 2017 - Apr 30, 2023 NIH The Contribution ofInfection to Preleukemic Clonal Hematopoiesis Role: Principal Investigator |
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K08HL098898 (KING, KATHERINE YUDEH)May 1, 2010 - Feb 28, 2015 NIH The Role of Interferon-gamma in the Regulation of Hematopoietic Stem Cells Role: Principal Investigator |
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T32HL092332 (HESLOP, HELEN E)Jul 1, 2003 - Jul 31, 2028 NIH Training In Cell and Gene Therapy Role: Co-Principal Investigator |