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DONGSU PARK

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
AddressOne Baylor Plaza
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    R01DE031288     (PARK, DONGSU)Jul 13, 2022 - Apr 30, 2027
    NIH
    Regulation of Skeletal progenitor cells in Osteogenesis Imperfecta
    Role: Principal Investigator
    R01DE031162     (LEE, BRENDAN)Sep 10, 2021 - Aug 31, 2026
    NIH
    WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal Tissues
    Role: Co-Principal Investigator
    R33AR078073     (MISHINA, YUJI)Sep 1, 2020 - Aug 31, 2024
    NIH
    A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclasts
    Role: Co-Principal Investigator
    R61AR078073     (MISHINA, YUJI)Sep 1, 2020 - Aug 31, 2022
    NIH
    A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclasts
    Role: Co-Principal Investigator
    R21AG064345     (DANG, WEIWEI)Jul 15, 2019 - Mar 31, 2021
    NIH
    Defining Periosteal Skeletal Stem Cell Heterogeneity and Age-associated Change
    Role: Co-Principal Investigator
    R01AR072018     (PARK, DONGSU)Jul 9, 2018 - Jun 30, 2025
    NIH
    Defining periosteal skeletal stem cells and novel migration mechanisms in bone regeneration and repair in vivo
    Role: Principal Investigator
    K01AR061434     (PARK, DONGSU)Aug 1, 2012 - Jul 31, 2017
    NIH
    Role of osteogenic stem cells in bone regeneration and repair in vivo
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Florez MA, Thatavarty A, Le DT, Hill HA, Jeong Y, Ho BM, Kus P, Wathan TK, Kain BN, Huang S, Park D, King KY, Florez MA, Thatavarty A, Le DT, Jeong Y, Ho BM, Wathan TK, Kain BN, Park D, King KY. BST2 facilitates activation of hematopoietic stem cells through ERK signaling. Exp Hematol. 2024 Dec; 140:104653. PMID: 39362577; PMCID: PMC11651051.
      Citations: 2     Fields:    Translation:AnimalsCells
    2. Marom R, Song IW, Busse EC, Washington ME, Berrier AS, Rossi VC, Ortinau L, Jeong Y, Jiang MM, Dawson BC, Adeyeye M, Leynes C, Lietman CD, Stroup BM, Batkovskyte D, Jain M, Chen Y, Cela R, Castellon A, Tran AA, Lorenzo I, Meyers DN, Huang S, Turner A, Shenava V, Wallace M, Orwoll E, Park D, Ambrose CG, Nagamani SC, Heaney JD, Lee BH, Marom R, Song IW, Busse EC, Washington ME, Berrier AS, Rossi VC, Ortinau L, Jeong Y, Jiang MM, Dawson BC, Adeyeye M, Leynes C, Lietman CD, Stroup BM, Batkovskyte D, Jain M, Chen Y, Cela R, Castellon A, Tran AA, Lorenzo I, Meyers DN, Huang S, Turner A, Shenava V, Wallace M, Orwoll E, Park D, Ambrose CG, Nagamani SC, Heaney JD, Lee BH. The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect. J Clin Invest. 2024 Jun 17; 134(15). PMID: 38885336; PMCID: PMC11290974.
      Citations: 6     Fields:    Translation:AnimalsCells
    3. Yang D, Solidum JGN, Park D. Dental Pulp Stem Cells and Current in vivo Approaches to Study Dental Pulp Stem Cells in Pulp Injury and Regeneration. J Bone Metab. 2023 Aug; 30(3):231-244. PMID: 37718901; PMCID: PMC10509030.
      Citations:    
    4. Yang D, Ortinau L, Jeong Y, Park D. Advances and challenges in intravital imaging of craniofacial and dental progenitor cells. Genesis. 2022 09; 60(8-9):e23498. PMID: 35980285; PMCID: PMC10015615.
      Citations:    
    5. Tovy A, Reyes JM, Zhang L, Huang YH, Rosas C, Daquinag AC, Guzman A, Ramabadran R, Chen CW, Gu T, Gupta S, Ortinau L, Park D, Cox AR, Rau RE, Hartig SM, Kolonin MG, Goodell MA. Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis. Elife. 2022 05 30; 11. PMID: 35635747; PMCID: PMC9150890.
      Citations: 21     Fields:    Translation:Animals
    6. Lim J, Lietman C, Grol MW, Castellon A, Dawson B, Adeyeye M, Rai J, Weis M, Keene DR, Schweitzer R, Park D, Eyre DR, Krakow D, Lee BH. Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta. Proc Natl Acad Sci U S A. 2021 06 22; 118(25). PMID: 34161280; PMCID: PMC8237619.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Grol MW, Haelterman NA, Lim J, Munivez EM, Archer M, Hudson DM, Tufa SF, Keene DR, Lei K, Park D, Kuzawa CD, Ambrose CG, Eyre DR, Lee BH. Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta. Elife. 2021 05 26; 10. PMID: 34036937; PMCID: PMC8186905.
      Citations:    Fields:    Translation:AnimalsCells
    8. Florez MA, Matatall KA, Jeong Y, Ortinau L, Shafer PW, Lynch AM, Jaksik R, Kimmel M, Park D, King KY. Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. Cell Rep. 2020 12 22; 33(12):108530. PMID: 33357430; PMCID: PMC7816211.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    9. Ortinau LC, Park D. Do adipogenic stromal cells undergo lineage plasticity in response to bone injury? Bioessays. 2021 01; 43(1):e2000296. PMID: 33616991; PMCID: PMC8162742.
      Citations:    Fields:    Translation:Cells
    10. Xu L, Liu X, Peng F, Zhang W, Zheng L, Ding Y, Gu T, Lv K, Wang J, Ortinau L, Hu T, Shi X, Shi G, Shang G, Sun S, Iwawaki T, Ji Y, Li W, Rosen JM, Zhang XH, Park D, Adoro S, Catic A, Tong W, Qi L, Nakada D, Chen X. Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nat Cell Biol. 2020 10; 22(10):1162-1169. PMID: 32958856; PMCID: PMC7888538.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    11. Ortinau L, Lei K, Jeong Y, Park D. Real-Time Imaging of CCL5-Induced Migration of Periosteal Skeletal Stem Cells in Mice. J Vis Exp. 2020 09 16; (163). PMID: 33016934; PMCID: PMC9119154.
      Citations:    Fields:    Translation:AnimalsCells
    12. Jeong Y, Park D. Targeting periosteal SSCs for aged bone defects. Aging (Albany NY). 2020 02 23; 12(4):3124-3125. PMID: 32090980; PMCID: PMC7066890.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Ortinau LC, Wang H, Lei K, Deveza L, Jeong Y, Hara Y, Grafe I, Rosenfeld SB, Lee D, Lee B, Scadden DT, Park D. Identification of Functionally Distinct Mx1+aSMA+ Periosteal Skeletal Stem Cells. Cell Stem Cell. 2019 12 05; 25(6):784-796.e5. PMID: 31809737; PMCID: PMC7055207.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    14. Ilenic N, Copar A, Pretnar A, Toplak M, Hartman J, Wang H, Bellazzi R, Garagna S, Zuccotti M, Park D, Shaulsky G, Godec P, Pancur M, Stra?ar M, Erjavec A, Dem?ar J, Staric A, ?agar L, Petrovic U, Zupan B. Democratized image analytics by visual programming through integration of deep models and small-scale machine learning. Nat Commun. 2019 10 07; 10(1):4551. PMID: 31591416; PMCID: PMC6779910.
      Citations: 22     Fields:    Translation:AnimalsCells
    15. Lee D, Ha M, Hong CM, Kim J, Park SM, Park D, Sohn DH, Shin HJ, Yu HS, Kim CD, Kang CD, Han ME, Oh SO, Kim YH. GABRQ expression is a potential prognostic marker for patients with clear cell renal cell carcinoma. Oncol Lett. 2019 Dec; 18(6):5731-5738. PMID: 31788046; PMCID: PMC6865077.
      Citations: 7     
    16. Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Brack AS, Crist C. Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell. 2019 06 06; 24(6):944-957.e5. PMID: 31006621; PMCID: PMC6597014.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    17. Ha M, Moon H, Choi D, Kang W, Kim JH, Lee KJ, Park D, Kang CD, Oh SO, Han ME, Kim YH, Lee D. Prognostic Role of TMED3 in Clear Cell Renal Cell Carcinoma: A Retrospective Multi-Cohort Analysis. Front Genet. 2019; 10:355. PMID: 31057605; PMCID: PMC6478656.
      Citations: 13     
    18. Lee EJ, Kim M, Kim YD, Chung MJ, Elfadl A, Ulah HMA, Park D, Lee S, Park HS, Kim TH, Hwang D, Jeong KS. Establishment of stably expandable induced myogenic stem cells by four transcription factors. Cell Death Dis. 2018 10 25; 9(11):1092. PMID: 30361642; PMCID: PMC6202407.
      Citations: 8     Fields:    Translation:AnimalsCells
    19. Deveza L, Ortinau L, Lei K, Park D. Comparative analysis of gene expression identifies distinct molecular signatures of bone marrow- and periosteal-skeletal stem/progenitor cells. PLoS One. 2018; 13(1):e0190909. PMID: 29342188; PMCID: PMC5771600.
      Citations: 11     Fields:    Translation:AnimalsCells
    20. Park D, Spencer JA, Lin CP, Scadden DT. Sequential in vivo imaging of osteogenic stem/progenitor cells during fracture repair. J Vis Exp. 2014 May 23; (87). PMID: 24894331; PMCID: PMC4206246.
      Citations: 4     Fields:    Translation:AnimalsCells
    21. Li X, Romain RD, Park D, Scadden DT, Merchant JL, Arnaout MA. Stress hematopoiesis is regulated by the Kr?ppel-like transcription factor ZBP-89. Stem Cells. 2014 Mar; 32(3):791-801. PMID: 24549639; PMCID: PMC3930080.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell. 2012 Mar 02; 10(3):259-72. PMID: 22385654; PMCID: PMC3652251.
      Citations: 298     Fields:    Translation:HumansAnimalsCells
    23. Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DM. Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814. PMID: 22303459; PMCID: PMC3267738.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    24. Park D, Sykes DB, Scadden DT. The hematopoietic stem cell niche. Front Biosci (Landmark Ed). 2012 01 01; 17(1):30-9. PMID: 22201730; PMCID: PMC4020275.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    25. Park D, Park I, Lee D, Choi YB, Lee H, Yun Y. The adaptor protein Lad associates with the G protein beta subunit and mediates chemokine-dependent T-cell migration. Blood. 2007 Jun 15; 109(12):5122-8. PMID: 17327418.
      Citations: 7     Fields:    Translation:HumansCells
    26. Park D, Lapteva N, Seethammagari M, Slawin KM, Spencer DM. An essential role for Akt1 in dendritic cell function and tumor immunotherapy. Nat Biotechnol. 2006 Dec; 24(12):1581-90. PMID: 17143278.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    27. Park D, Yun Y. Tyrosine phosphorylation-dependent yeast two-hybrid system for the identification of the SH2 domain-binding proteins. Mol Cells. 2001 Oct 31; 12(2):244-9. PMID: 11710529.
      Citations: 3     Fields:    Translation:AnimalsCells
    28. Park D, Choi YB, Han MK, Kim UH, Shin J, Yun Y. Adaptor protein Lad relays PDGF signal to Grb2 in lung cells: a tissue-specific PDGF signal transduction. Biochem Biophys Res Commun. 2001 Jun 08; 284(2):275-81. PMID: 11394873.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    29. Park D, Kim H, Chung K, Kim DS, Yun Y. Expression and characterization of a novel plasminogen activator from Agkistrodon halys venom. Toxicon. 1998 Dec; 36(12):1807-19. PMID: 9839665.
      Citations: 10     Fields:    Translation:AnimalsCells
    30. Park D, Kang I, Kim H, Chung K, Kim DS, Yun Y. Cloning and characterization of novel disintegrins from Agkistrodon halys venom. Mol Cells. 1998 Oct 31; 8(5):578-84. PMID: 9856345.
      Citations: 9     Fields:    Translation:AnimalsCells
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