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RACHEL RAU

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
AddressOne Baylor Plaza
Houston, 77030
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    K08CA201611     (RAU, RACHEL E)Apr 1, 2017 - Mar 31, 2020
    NIH
    DEFINING THE ROLE OF DOT1L IN DNMT3A-MUTANT LEUKEMIA
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Maese LD, Loh ML, Choi MR, Agarwal S, Aoki E, Liang Y, Lin T, Girgis S, Chen C, Roller SG, Chandrasekaran V, Iannone R, Silverman LB, Raetz EA, Rau RE. Recombinant Erwinia Asparaginase (JZP458) in ALL/LBL: Complete Follow-Up of the Children's Oncology Group AALL1931 Study. Blood Adv. 2024 Oct 25. PMID: 39454281.
      Citations:    Fields:    
    2. Kodali S, Proietti L, Valcarcel G, L?pez-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupi?n-Garcia N, Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Mart?nez A, Velasco-Hernandez T, Tom?s-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL, Grebien F, Di Stefano B. RNA sequestration in P-bodies sustains myeloid leukaemia. Nat Cell Biol. 2024 Oct; 26(10):1745-1758. PMID: 39169219.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Kumar RD, Vossaert L, Bi W, Owen N, Rau RE, Helber HL, Sasa G, Reuther J, Roy A, Fisher KE. Brain abscesses, neutropenia, and B-ALL: Multiple testing modalities required to confirm PDCD10 and ETV6 dual diagnoses. Cancer Genet. 2024 Aug 15; 288-289:5-9. PMID: 39178500.
      Citations:    Fields:    
    4. Rau RE. 'Roids without rage via B-cell-targeted ADC? Blood. 2024 08 15; 144(7):686-687. PMID: 39145946.
      Citations:    Fields:    Translation:HumansCells
    5. Lucas BJ, Connors JS, Wang H, Conneely S, Cuglievan B, Garcia MB, Rau RE. Observation and Management of Juvenile Myelomonocytic Leukemia and Noonan Syndrome-Associated Myeloproliferative Disorder: A Real-World Experience. Cancers (Basel). 2024 Aug 02; 16(15). PMID: 39123476; PMCID: PMC11311611.
      Citations:    
    6. Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando TA, Brunet A, Parchem RJ, Rau RE, Goodell MA. Erratum: Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation. iScience. 2024 Jul 19; 27(7):110313. PMID: 39027369; PMCID: PMC11255835.
      Citations:    
    7. Rogers JH, Rosen A, Reyes JM, Ketkar S, Conneely SE, Gupta R, Yang L, Miller MB, Medrano G, Aguilar R, Uchenda N, Goodell MA, Rau RE. Dose-dependent effects of Dnmt3a in an inducible murine model of KrasG12D-driven leukemia. Exp Hematol. 2024 Jul; 135:104248. PMID: 38834136; PMCID: PMC11288274.
      Citations:    Fields:    Translation:Animals
    8. Lamble AJ, Rau RE. IFN-? and CD38 in AML: a T-cell engagement made in heaven? Blood. 2024 04 18; 143(16):1556-1557. PMID: 38635257.
      Citations:    Fields:    Translation:HumansCells
    9. DelRocco NJ, Loh ML, Borowitz MJ, Gupta S, Rabin KR, Zweidler-McKay P, Maloney KW, Mattano LA, Larsen E, Angiolillo A, Schore RJ, Burke MJ, Salzer WL, Wood BL, Carroll AJ, Heerema NA, Reshmi SC, Gastier-Foster JM, Harvey R, Chen IM, Roberts KG, Mullighan CG, Willman C, Winick N, Carroll WL, Rau RE, Teachey DT, Hunger SP, Raetz EA, Devidas M, Kairalla JA. Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report. Leukemia. 2024 Apr; 38(4):720-728. PMID: 38360863; PMCID: PMC10997503.
      Citations: 2     Fields:    Translation:Humans
    10. Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando T, Brunet A, Parchem RJ, Rau RE, Goodell MA, Rando TA. Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation. iScience. 2024 Mar 15; 27(3):109122. PMID: 38414863; PMCID: PMC10897855.
      Citations: 2     
    11. Conneely SE, Rau RE. Fusion and flow: refining risk prediction in KMT2A-rearranged pediatric acute myeloid leukemia. Transl Pediatr. 2023 Dec 26; 12(12):2099-2102. PMID: 38197101; PMCID: PMC10772840.
      Citations:    
    12. Withycombe JS, Kubaney HR, Okada M, Yun CS, Gupta S, Bloom C, Parker V, Rau RE, Zupanec S. Delivery of Care for Pediatric Patients Receiving Blinatumomab: A Children's Oncology Group Study. Cancer Nurs. 2024 Nov-Dec 01; 47(6):451-459. PMID: 38016041; PMCID: PMC11128477.
      Citations:    Fields:    
    13. Kumar P, Zhang N, Lee J, Cheng H, Kurtz K, Conneely SE, Sasidharan R, Rau RE, Pati D. Cohesin Subunit RAD21 Regulates the Differentiation and Self-Renewal of Hematopoietic Stem and Progenitor Cells. Stem Cells. 2023 10 08; 41(10):971-985. PMID: 37534584.
      Citations:    Fields:    Translation:AnimalsCells
    14. Elgarten CW, Kairalla JA, Thompson JC, Miller TP, Wang C, Conway S, Loh ML, Raetz EA, Gupta S, Rau RE, Angiolillo A, Rabin KR, Alexander S. SARS-CoV-2 infections in patients enrolled on the Children's Oncology Group standard-risk B-cell acute lymphoblastic leukemia trial, AALL1731. EJHaem. 2023 Aug; 4(3):745-750. PMID: 37601850; PMCID: PMC10435702.
      Citations: 1     
    15. Ramabadran R, Wang JH, Reyes JM, Guzman AG, Gupta S, Rosas C, Brunetti L, Gundry MC, Tovy A, Long H, Gu T, Cullen SM, Tyagi S, Rux D, Kim JJ, Kornblau SM, Kyba M, Stossi F, Rau RE, Takahashi K, Westbrook TF, Goodell MA. DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 04; 25(4):528-539. PMID: 37024683; PMCID: PMC10337578.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Chambers C, Cermakova K, Chan YS, Kurtz K, Wohlan K, Lewis AH, Wang C, Pham A, Dejmek M, Sala M, Loeza Cabrera M, Aguilar R, Nencka R, Lacorazza HD, Rau RE, Hodges HC. SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia. Cancer Res. 2023 04 04; 83(7):983-996. PMID: 36662812; PMCID: PMC10071820.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Fries C, Lee LW, Devidas M, Dai Y, Rabin KR, Gupta S, Loh ML, Kirsch IR, Wood B, Rau RE. Prognostic impact of pretreatment immunoglobulin clonal composition in pediatric B-lymphoblastic leukemia. Haematologica. 2023 03 01; 108(3):900-904. PMID: 36325891; PMCID: PMC9973485.
      Citations: 1     Fields:    Translation:Humans
    18. Kurtz KJ, Conneely SE, O'Keefe M, Wohlan K, Rau RE. Corrigendum: Murine models of acute myeloid leukemia. Front Oncol. 2022; 12:1089874. PMID: 36911791; PMCID: PMC9997673.
      Citations:    
    19. Maese L, Loh ML, Choi MR, Lin T, Aoki E, Zanette M, Agarwal S, Iannone R, Silverman JA, Silverman LB, Raetz EA, Rau RE. Recombinant Erwinia asparaginase (JZP458) in acute lymphoblastic leukemia: results from the phase 2/3 AALL1931 study. Blood. 2023 02 16; 141(7):704-712. PMID: 36108304; PMCID: PMC10651770.
      Citations:    
    20. Pinchinat A, Gupta S, Cooper SL, Rau RE. SOHO State of the Art Updates and Next Questions | Optimal Timing of Blinatumomab for the Treatment of B-Acute Lymphoblastic Leukemia. Clin Lymphoma Myeloma Leuk. 2023 03; 23(3):159-167. PMID: 36642665.
      Citations:    Fields:    Translation:Humans
    21. Elgarten CW, Thompson JC, Angiolillo A, Chen Z, Conway S, Devidas M, Gupta S, Kairalla JA, McNeer JL, O'Brien MM, Rabin KR, Rau RE, Rheingold SR, Wang C, Wood C, Raetz EA, Loh ML, Alexander S, Miller TP. Improving infectious adverse event reporting for children and adolescents enrolled in clinical trials for acute lymphoblastic leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2022 11; 69(11):e29937. PMID: 36083863; PMCID: PMC9529813.
      Citations:    
    22. Maese L, Rau RE. Current Use of Asparaginase in Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. Front Pediatr. 2022; 10:902117. PMID: 35844739; PMCID: PMC9279693.
      Citations:    
    23. Kurtz KJ, Conneely SE, O'Keefe M, Wohlan K, Rau RE. Murine Models of Acute Myeloid Leukemia. Front Oncol. 2022; 12:854973. PMID: 35756660; PMCID: PMC9214208.
      Citations:    
    24. Tovy A, Reyes JM, Zhang L, Huang YH, Rosas C, Daquinag AC, Guzman A, Ramabadran R, Chen CW, Gu T, Gupta S, Ortinau L, Park D, Cox AR, Rau RE, Hartig SM, Kolonin MG, Goodell MA. Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis. Elife. 2022 05 30; 11. PMID: 35635747; PMCID: PMC9150890.
      Citations: 1     Fields:    Translation:Animals
    25. Tovy A, Rosas C, Gaikwad AS, Medrano G, Zhang L, Reyes JM, Huang YH, Arakawa T, Kurtz K, Conneely SE, Guzman AG, Aguilar R, Gao A, Chen CW, Kim JJ, Carter MT, Lasa-Aranzasti A, Valenzuela I, Brunetti L, Hicks MJ, Marcogliese AN, Goodell MA, Rau RE, Van Maldergem L. Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome. Haematologica. 2022 04 01; 107(4):887-898. PMID: 34092059; PMCID: PMC8968878.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    26. Conneely SE, McAtee CL, Gupta R, Lubega J, Scheurer ME, Rau RE. Association of race and ethnicity with clinical phenotype, genetics, and survival in pediatric acute myeloid leukemia. Blood Adv. 2021 12 14; 5(23):4992-5001. PMID: 34619758; PMCID: PMC9153027.
      Citations:    Fields:    Translation:Humans
    27. Rau RE. A viral cause of APL. Blood. 2021 11 04; 138(18):1653-1655. PMID: 34734999.
      Citations:    Fields:    
    28. Rogers JH, Gupta R, Reyes JM, Gundry MC, Medrano G, Guzman A, Aguilar R, Conneely SE, Song T, Johnson C, Barnes S, Cristobal CDD, Kurtz K, Brunetti L, Goodell MA, Rau RE. Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities. Blood Adv. 2021 10 12; 5(19):3876-3890. PMID: 34492683; PMCID: PMC8679666.
      Citations:    Fields:    Translation:HumansAnimals
    29. Gupta S, Cooper SL, RAU RE. Optimal Timing of Blinatumomab for the Treatment of B-Lymphoblastic Leukemia. Clinical Lymphoma, Myeloma and Leukemia. 2021; 6(21):S99-S101. View Publication.
    30. Maese L, Rizzari C, Coleman R, Power A, Rau RE, van der Sluis I. Can recombinant technology address asparaginase Erwinia chrysanthemi shortages? Pediatr Blood Cancer. 2021 10; 68(10):e29169. PMID: 34105243.
      Citations: 5     Fields:    Translation:HumansCells
    31. Rau RE, Dai Y, Devidas M, Rabin KR, Zweidler-McKay P, Angiolillo A, Schore RJ, Burke MJ, Salzer WL, Heerema NA, Carroll AJ, Winick NJ, Hunger SP, Raetz EA, Loh ML, Wood BL, Borowitz MJ. Prognostic impact of minimal residual disease at the end of consolidation in NCI standard-risk B-lymphoblastic leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2021 04; 68(4):e28929. PMID: 33559396; PMCID: PMC8808711.
      Citations:    Fields:    Translation:Humans
    32. Junco JJ, Chen T, Rashid R, Terrell M, Gant VU, Miller M, Rau R, Lacorazza HD, Rabin KR. An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance. Leukemia. 2021 06; 35(6):1777-1781. PMID: 32918044; PMCID: PMC10204645.
      Citations: 1     Fields:    Translation:Animals
    33. Gupta S, Maude SL, O'Brien MM, Rau RE, McNeer JL. How the COG is Approaching the High-Risk Patient with ALL: Incorporation of Immunotherapy into Frontline Treatment. Clin Lymphoma Myeloma Leuk. 2020 09; 20 Suppl 1:S8-S11. PMID: 32862880.
      Citations:    Fields:    Translation:Humans
    34. Conneely SE, Cooper SL, Rau RE. Use of Allopurinol to Mitigate 6-Mercaptopurine Associated Gastrointestinal Toxicity in Acute Lymphoblastic Leukemia. Front Oncol. 2020; 10:1129. PMID: 32766146; PMCID: PMC7378397.
      Citations: 1     
    35. Rau RE. SIRPAssing other xenograft murine models? Blood. 2020 05 07; 135(19):1612-1614. PMID: 32379878.
      Citations:    Fields:    Translation:HumansAnimalsCells
    36. McNeer JL, Rau RE, Gupta S, Maude SL, O'Brien MM. Cutting to the Front of the Line: Immunotherapy for Childhood Acute Lymphoblastic Leukemia. Am Soc Clin Oncol Educ Book. 2020 Mar; 40:1-12. PMID: 32320280.
      Citations: 6     Fields:    Translation:Humans
    37. Conneely SE, Rau RE. The genomics of acute myeloid leukemia in children. Cancer Metastasis Rev. 2020 03; 39(1):189-209. PMID: 31925603; PMCID: PMC7324027.
      Citations: 12     Fields:    Translation:Humans
    38. Rossoff J, Huynh V, Rau RE, Macy ME, Sulis ML, Schultz KR, Burke MJ, Athale U, O'Brien MM, Gregory JJ, Keller FG, Suttorp M, Hijiya N, van der Sluis IM, Zwaan CM. Experience with ponatinib in paediatric patients with leukaemia. Br J Haematol. 2020 04; 189(2):363-368. PMID: 31975387.
      Citations: 4     Fields:    Translation:Humans
    39. Park CS, Lewis AH, Chen TJ, Bridges CS, Shen Y, Suppipat K, Puppi M, Tomolonis JA, Pang PD, Mistretta TA, Ma L, Green MR, Rau R, Lacorazza HD. A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells. Blood. 2019 11 28; 134(22):1960-1972. PMID: 31515251; PMCID: PMC6887114.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    40. Hashmi SK, Navai SA, Chambers TM, Scheurer ME, Hicks MJ, Rau RE, Gramatges MM. Incidence and predictors of treatment-related conjugated hyperbilirubinemia during early treatment phases for children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2020 02; 67(2):e28063. PMID: 31736183; PMCID: PMC7382403.
      Citations: 3     Fields:    Translation:Humans
    41. Schafer ES, Rau RE, Berg SL, Liu X, Minard CG, Bishop AJR, Romero JC, Hicks MJ, Nelson MD, Voss S, Reid JM, Fox E, Weigel BJ, Blaney SM. Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411). Pediatr Blood Cancer. 2020 02; 67(2):e28073. PMID: 31724813; PMCID: PMC9134216.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    42. Gruner SE, Sayeed H, Suarez-Ferguson L, Perez C, Rouce R, Fisher KE, Rau RE. Ponatinib use in two pediatric patients with relapsed Ph?+?ALL with ABL1 kinase domain mutations. Pediatr Hematol Oncol. 2019 11; 36(8):514-519. PMID: 31510844.
      Citations: 1     Fields:    Translation:Humans
    43. Hashmi SK, Punia JN, Marcogliese AN, Gaikwad AS, Fisher KE, Roy A, Rao P, Lopez-Terrada DH, Ringrose J, Loh ML, Niemeyer CM, Rau RE. Sustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia. Pediatr Blood Cancer. 2019 10; 66(10):e27905. PMID: 31250550; PMCID: PMC7328527.
      Citations: 3     Fields:    Translation:HumansCells
    44. Rau RE, Goodell MA. Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning. Cell Stem Cell. 2019 04 04; 24(4):511-512. PMID: 30951659.
      Citations:    Fields:    Translation:Cells
    45. Miller MB, Brackett J, Schafer ES, Rau RE. Prevention of mercaptopurine-induced hypoglycemia using allopurinol to reduce methylated thiopurine metabolites. Pediatr Blood Cancer. 2019 04; 66(4):e27577. PMID: 30548777.
      Citations: 4     Fields:    Translation:Humans
    46. Rau RE, Loh ML. Using genomics to define pediatric blood cancers and inform practice. Hematology Am Soc Hematol Educ Program. 2018 11 30; 2018(1):286-300. PMID: 30504323; PMCID: PMC6245969.
      Citations: 3     Fields:    Translation:Humans
    47. Annesley CE, Rabik C, Duffield AS, Rau RE, Magoon D, Li L, Huff V, Small D, Loeb DM, Brown P. Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice. Oncotarget. 2018 Oct 19; 9(82):35313-35326. PMID: 30450160; PMCID: PMC6219680.
      Citations: 6     Fields:    
    48. Schraw JM, Yiu TT, Lupo PJ, Tsavachidis S, Rau R, Bondy ML, Rabin KR, Shen L, Scheurer ME. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408. PMID: 29763473; PMCID: PMC5953491.
      Citations: 2     Fields:    Translation:HumansCells
    49. Schafer ES, Rau RE, Berg S, Liu X, Minard CG, D'Adamo D, Scott R, Reyderman L, Martinez G, Devarajan S, Reid JM, Fox E, Weigel BJ, Blaney SM. A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: A Children's Oncology Group Phase 1 Consortium study (ADVL1314). Pediatr Blood Cancer. 2018 08; 65(8):e27066. PMID: 29719113; PMCID: PMC6019176.
      Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
    50. Rau RE, Dreyer Z, Choi MR, Liang W, Skowronski R, Allamneni KP, Devidas M, Raetz EA, Adamson PC, Blaney SM, Loh ML, Hunger SP. Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2018 03; 65(3). PMID: 29090524; PMCID: PMC5839116.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    51. Rau RE. CMML/JMML PDXs: as easy as 1, 2, NSG-SGM3. Blood. 2017 07 27; 130(4):385-386. PMID: 28751353.
      Citations: 1     Fields:    Translation:HumansAnimals
    52. Heikamp E, Rau R. 50 Years Ago in The Journal of Pediatrics: Sequential Therapy of Acute Leukemia in Childhood. J Pediatr. 2017 04; 183:140. PMID: 28343531.
      Citations:    Fields:    Translation:Humans
    53. Gramatges MM, Deshpande A, Lupo PJ, Rau RE, Redell ML, Horton TM, Scheurer ME, Rabin KR. Ethnic disparities relative to disease features and outcomes in children with acute myeloid leukemia. Pediatr Blood Cancer. 2017 Sep; 64(9). PMID: 28266784.
      Citations: 5     Fields:    Translation:Humans
    54. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Lee JS, Rau R, Li W, Goodell MA, G?ttgens B. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 08 08; 30(2):363-365. PMID: 27505680.
      Citations: 20     Fields:    
    55. Rau RE, Carroll AJ, Arland L, Carroll WL, Winick NJ, Raetz EA, Loh ML, Yang W, Relling MV, Dai Y, Devidas M, Hunger SP, Heerema NA. Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia. Br J Haematol. 2017 12; 179(5):843-846. PMID: 27434379; PMCID: PMC5247399.
      Citations: 2     Fields:    Translation:Humans
    56. Rau RE, Rodriguez BA, Luo M, Jeong M, Rosen A, Rogers JH, Campbell CT, Daigle SR, Deng L, Song Y, Sweet S, Chevassut T, Andreeff M, Kornblau SM, Li W, Goodell MA. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81. PMID: 27335278; PMCID: PMC4990856.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    57. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Gottgens B, Lee JS, Rau R, Li W, Goodell MA. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 06 13; 29(6):922-934. PMID: 27300438; PMCID: PMC4908977.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    58. Rau RE. Beyond KIT in CBF-AML: chromatin and cohesin. Blood. 2016 05 19; 127(20):2370-1. PMID: 27207321; PMCID: PMC9278272.
      Citations: 3     Fields:    Translation:Cells
    59. Eckstein OS, Wang L, Punia JN, Kornblau SM, Andreeff M, Wheeler DA, Goodell MA, Rau RE. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 08; 44(8):740-4. PMID: 27208809; PMCID: PMC4956537.
      Citations: 17     Fields:    Translation:HumansCells
    60. Schafer ES, RAU RE, Liu X, Minard, CG, D’Adamo D, Scott R, Reyderman L, Martinez G, Fox E, Weigel BJ, Blaney SB. A phase 1 study of eribulin mesylate (E7389), a novel microtubule targeting chemotherapeutic agent in children with refractory or recurrent solid tumors (excluding CNS), including lymphomas: a Children’s Oncology Group Phase 1 Consortium study (ADVL1314). American Society of Clinical Oncology Annual Meeting. Poster presentation. Abstract #2567. 2016.
    61. RAU R, Brackett J. Prevention of mercaptopurine-induced hypoglycemia using allopurinol to reduce methylated thiopurine metabolites. American Society of Pediatric Hematology-Oncology Annual Meeting Abstracts. 2016.
    62. Annesley CE, Duffield AS, RAU RE, McCarty G, Magoon D, Li L, Huff V, Small D, Loeb D, Brown P. A Wilms Tumor 1 (WT1) Mutation Causes Myelodysplastic Syndrome in a Knock-in Mouse Model, and a Mixed Myelodysplastic/Myeloproliferative Neoplam in Double Knock-in Mice with WT1 and FLT3/ITD Mutations. Blood. 2015; 23(126).
    63. Cohen G, Annesley CE, RAU RE, Kelley S, Magoon D, Brown P. Targeting BCL6-Mediated Resistance to BCR-ABL Targeted Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) through the Addition of Histone Deacetylase (HDAC) Inhibitors. Blood. 2015; 23(126):1277.
    64. Deshpande A, Gramatges MM, Sasa GS, Lupo PJ, RAU RE, Redell MS, Horton TM, Scheurer ME, Rabin KR. Poorer relapse-free survival in hispanic children diagnosed with acute myeloid leukemia compared with non-hispanics: a Texas single institution experience. Blood. 2015; 23(126).
    65. Sayeed H, Fisher K, Gramatges M, Somvanshi S, RAU RE, Merritt BY, Roy A, Marcogliese A, Punia JN, Horton TM, Bertuch AA, Redell ML, Rabin KR, López-Terrada D. A customized targeted next-generation sequencing mutation panel for clinical use in pediatric hematologic malignancies: a pilot study. Blood. 2015; 23(126).
    66. Yang L, Rau R, Goodell MA. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65. PMID: 25693834; PMCID: PMC5814392.
      Citations: 188     Fields:    Translation:HumansCells
    67. Sison EA, Magoon D, Li L, Annesley CE, Rau RE, Small D, Brown P. Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition. Oncotarget. 2014 Oct 15; 5(19):8947-58. PMID: 25333254; PMCID: PMC4253409.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    68. Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21; 20(11):1352-63. PMID: 24183972; PMCID: PMC3881547.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    69. Rau R, Magoon D, Greenblatt S, Li L, Annesley C, Duffield AS, Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease. Exp Hematol. 2014 Feb; 42(2):101-13.e5. PMID: 24184354; PMCID: PMC3932758.
      Citations: 20     Fields:    Translation:AnimalsCells
    70. Sison EA, Rau RE, McIntyre E, Li L, Small D, Brown P. MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism. Br J Haematol. 2013 Mar; 160(6):785-97. PMID: 23294096; PMCID: PMC4005340.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    71. Karafin M, Romagnoli M, Fink DL, Howard T, Rau R, Milstone AM, Carroll KC. Fatal infection caused by Cupriavidus gilardii in a child with aplastic anemia. J Clin Microbiol. 2010 Mar; 48(3):1005-7. PMID: 20071544; PMCID: PMC2832434.
      Citations: 19     Fields:    Translation:HumansCells
    72. Rau R, Brown P. Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity. Hematol Oncol. 2009 Dec; 27(4):171-81. PMID: 19569254; PMCID: PMC3069851.
      Citations: 41     Fields:    Translation:Humans
    73. Rau R, Fitzhugh CD, Baird K, Cortez KJ, Li L, Fischer SH, Cowen EW, Balow JE, Walsh TJ, Cohen JI, Wayne AS. Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: utility of PCR for early recognition and therapy. Pediatr Infect Dis J. 2008 Mar; 27(3):265-8. PMID: 18277922.
      Citations: 11     Fields:    Translation:HumansCells
    74. Brown P, McIntyre E, Rau R, Meshinchi S, Lacayo N, Dahl G, Alonzo TA, Chang M, Arceci RJ, Small D. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood. 2007 Aug 01; 110(3):979-85. PMID: 17440048; PMCID: PMC1924773.
      Citations: 68     Fields:    Translation:HumansCells
    75. Cordero L, Rau R, Taylor D, Ayers LW. Enteric gram-negative bacilli bloodstream infections: 17 years' experience in a neonatal intensive care unit. Am J Infect Control. 2004 Jun; 32(4):189-95. PMID: 15175611.
      Citations: 31     Fields:    Translation:HumansCells
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