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SHOBA NAVAI

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
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    Collapse Biography 
    Collapse education and training
    Medical College of Georgia, Augusta, GeorgiaMD05/2010Medicine
    Baylor College of Medicine, Houston, Texas06/2014Residency in Pediatrics and Global Child Health
    Baylor College of Medicine, Houston, Texas09/2017Fellowship in Pediatric Hematology/Oncology

    Collapse Research 
    Collapse research activities and funding
         (Meenakshi Hegde)Jan 1, 2021 - Dec 31, 2023
    The Faris Foundation
    HEROS 3.0 Clinical Trial
         (Shoba Navai)Jan 1, 2021 - Dec 31, 2021
    Curing Kids Cancer
    Cancer Immunotherapy Scholar Award
    K12CA090433     (BLANEY, SUSAN M.)Apr 1, 2001 - Jun 30, 2027
    NIH
    PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAM
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Landi D, Navai SA, Brock RM, Fousek K, Nawas Z, Sanber K, Chauvin-Fleurence C, Bhat RR, Xu S, Krishnamurthy P, Choe M, Campbell M, Morris JS, Gad AZ, Shree A, Echeandia A, Saadeldin A, Matthew PR, Mullikin D, Bielamowicz K, Kurenbekova L, Major AM, Salsman VS, Byrd TT, Hicks MJ, Zhang YJ, Yustein J, Carisey AF, Joseph SK, Ahmed N, Hegde M. A checkpoint reversal receptor mediates bipartite activation and enhances CAR T-cell function. Cancer Res Commun. 2025 Feb 20. PMID: 39973814.
      Citations:    Fields:    
    2. Ross AB, Puri K, Johnson TL, Correa LD, John TD, Friend B, Navai SA, Ahmed N, Hegde MG, Omer B, Heczey A, Salem BM, Tcharmtchi H, Rouce RH, Steffin DH, Krance RA, Rainusso NC, Bhar S. Cardiovascular Complications of Immune Effector Cell Therapies in Pediatric Hematological and Solid Tumors. Pediatr Blood Cancer. 2025 Apr; 72(4):e31557. PMID: 39833487.
      Citations:    Fields:    
    3. Navai SA, Mahajan P, Venkatramani R. National virtual tumor boards to inform the management of children with rare cancers. Curr Opin Pediatr. 2025 Feb 01; 37(1):56-58. PMID: 39699101.
      Citations:    Translation:Humans
    4. Miller A, Daum R, Wang T, Wu M, Tat C, Pfeiffer T, Navai S, Heczey A, Hegde M, Ahmed N, Whittle SB, Hill L, Martinez C, Krance R, Ramos CA, Rouce RH, Lulla P, Heslop HE, Omer B, Shekar M. Prolonged cytopenias after immune effector cell therapy and lymphodepletion in patients with leukemia, lymphoma and solid tumors. Cytotherapy. 2024 Sep; 26(9):1026-1032. PMID: 38819365; PMCID: PMC11344664.
      Citations: 1     Fields:    Translation:HumansCells
    5. Hegde M, Navai S, DeRenzo C, Joseph SK, Sanber K, Wu M, Gad AZ, Janeway KA, Campbell M, Mullikin D, Nawas Z, Robertson C, Mathew PR, Zhang H, Mehta B, Bhat RR, Major A, Shree A, Gerken C, Kalra M, Chakraborty R, Thakkar SG, Dakhova O, Salsman VS, Grilley B, Lapteva N, Gee A, Dotti G, Bao R, Salem AH, Wang T, Brenner MK, Heslop HE, Wels WS, Hicks MJ, Gottschalk S, Ahmed N. Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nat Cancer. 2024 Jun; 5(6):880-894. PMID: 38658775; PMCID: PMC11588040.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    6. Mahajan P, Navai S, Smith V, Potter S, Venkatramani R. Advancing the Care of Pediatric Rare Solid Tumors: A virtual rare tumor board. Pediatr Hematol Oncol. 2022 10; 39(7):678-680. PMID: 35262463.
      Citations:    Fields:    
    7. Baday YI, Navai SA, Hicks MJ, Venkatramani R, Whittle SB. Pediatric liposarcoma: A case series and literature review. Pediatr Blood Cancer. 2021 12; 68(12):e29327. PMID: 34520106.
      Citations: 1     Fields:    Translation:Humans
    8. Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2021 07 01; 131(13). PMID: 34196303; PMCID: PMC8245163.
      Citations: 2     Fields:    
    9. Smith VR, Whittle SB, Coleman RD, Munoz FM, De Guzman MM, Foster JH, Navai SA. Severe COVID-19 infection in a child receiving immunotherapy for cancer. Pediatr Blood Cancer. 2021 03; 68(3):e28710. PMID: 32930438; PMCID: PMC7861044.
      Citations: 4     Fields:    Translation:HumansCells
    10. Hegde M, Joseph SK, Pashankar F, DeRenzo C, Sanber K, Navai S, Byrd TT, Hicks J, Xu ML, Gerken C, Kalra M, Robertson C, Zhang H, Shree A, Mehta B, Dakhova O, Salsman VS, Grilley B, Gee A, Dotti G, Heslop HE, Brenner MK, Wels WS, Gottschalk S, Ahmed N. Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma. Nat Commun. 2020 07 15; 11(1):3549. PMID: 32669548; PMCID: PMC7363864.
      Citations: 33     Fields:    Translation:HumansCells
    11. Fousek K, Watanabe J, Joseph SK, George A, An X, Byrd TT, Morris JS, Luong A, Sanber K, Navai SA, Gad AZ, Salsman VS, Mathew PR, Kim HN, Wagner DL, Brunetti L, Jang A, Baker ML, Varadarajan N, Hegde M, Kim YM, Heisterkamp N, Abdel-Azim H, Ahmed N, Mart?nez-Paniagua MA. CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression. Leukemia. 2021 01; 35(1):75-89. PMID: 32205861; PMCID: PMC7519582.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    12. Hashmi SK, Navai SA, Chambers TM, Scheurer ME, Hicks MJ, Rau RE, Gramatges MM. Incidence and predictors of treatment-related conjugated hyperbilirubinemia during early treatment phases for children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2020 02; 67(2):e28063. PMID: 31736183; PMCID: PMC7382403.
      Citations: 3     Fields:    Translation:Humans
    13. Danysh HE, Navai SA, Scheurer ME, Hunt R, Venkatramani R. Malignant melanoma incidence among children and adolescents in Texas and SEER 13, 1995-2013. Pediatr Blood Cancer. 2019 06; 66(6):e27648. PMID: 30729662; PMCID: PMC6472974.
      Citations: 2     Fields:    Translation:Humans
    14. Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2016 08 01; 126(8):3036-52. PMID: 27427982; PMCID: PMC4966331.
      Citations: 249     Fields:    Translation:HumansAnimalsCells
    15. Navai SA, Ahmed N. Targeting the tumour profile using broad spectrum chimaeric antigen receptor T-cells. Biochem Soc Trans. 2016 Apr 15; 44(2):391-6. PMID: 27068945.
      Citations: 9     Fields:    Translation:Humans
    16. Reddy-Holdcraft S, Mehta PS, Agrawal AK. Paclitaxel for relapsed or recurrent HIV-associated pediatric Kaposi's sarcoma. AIDS. 2014 Mar 13; 28(5):800-2. PMID: 24983546.
      Citations: 3     Fields:    Translation:Humans
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