Header Logo

DIMITRIOS LAURIN WAGNER

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentCenter for Cell & Gene Therapy
Address1102 BATES
Houston, TX 77030
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, K?nkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pru? A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Integration of ?-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. Blood. 2024 Mar 17. PMID: 38493479.
      Citations:    Fields:    
    2. Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, K?nkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pru? A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Integration of ?-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. bioRxiv. 2023 Nov 14. PMID: 38116030; PMCID: PMC10729737.
      Citations:    
    3. Wagner DL, Ostendorf L. New dawn of cellular therapies in autoimmune diseases. Mol Ther Methods Clin Dev. 2023 Dec 14; 31:101141. PMID: 38027062; PMCID: PMC10661845.
      Citations:    
    4. Kath J, Du W, Martini S, Elsallab M, Franke C, Hartmann L, Drosdek V, Glaser V, Stein M, Schmueck-Henneresse M, Reinke P, Volk HD, Abou-El-Enein M, Wagner DL. CAR NK-92 cell-mediated depletion of residual TCR+ cells for ultrapure allogeneic TCR-deleted CAR T-cell products. Blood Adv. 2023 08 08; 7(15):4124-4134. PMID: 37196643; PMCID: PMC10388728.
      Citations:    
    5. Wagner DL, Mamonkin M. Splendid isolation. Blood. 2023 06 01; 141(22):2665-2666. PMID: 37261853.
      Citations:    Fields:    Translation:Cells
    6. Glaser V, Flugel C, Kath J, Du W, Drosdek V, Franke C, Stein M, Pru? A, Schmueck-Henneresse M, Volk HD, Reinke P, Wagner DL. Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells. Genome Biol. 2023 04 24; 24(1):89. PMID: 37095570; PMCID: PMC10123993.
      Citations:    
    7. Braun T, Pruene A, Darguzyte M, Vom Stein AF, Nguyen PH, Wagner DL, Kath J, Roig-Merino A, Heuser M, Riehm LL, Schneider A, Awerkiew S, Talbot SR, Bleich A, Figueiredo C, Bornh?user M, Stripecke R. Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency. Front Immunol. 2023; 14:1086433. PMID: 37033919; PMCID: PMC10081580.
      Citations:    
    8. Ostendorf L, Burns M, Wagner DL, Enghard P, Amann K, Mei H, Eckardt KU, Seelow E, Schreiber A. Daratumumab for the treatment of refractory ANCA-associated vasculitis. RMD Open. 2023 01; 9(1). PMID: 36627149; PMCID: PMC9835944.
      Citations:    
    9. Flugel CL, Majzner RG, Krenciute G, Dotti G, Riddell SR, Wagner DL, Abou-El-Enein M. Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours. Nat Rev Clin Oncol. 2023 01; 20(1):49-62. PMID: 36418477; PMCID: PMC10278599.
      Citations:    
    10. Gottschalk I, K?lsch U, Wagner DL, Kath J, Martini S, Kr?ger R, Puel A, Casanova JL, Jezela-Stanek A, Rossi R, Chehadeh SE, Van Esch H, von Bernuth H. IRAK1 Duplication in MECP2 Duplication Syndrome Does Not Increase Canonical NF-?B-Induced Inflammation. J Clin Immunol. 2023 02; 43(2):421-439. PMID: 36319802; PMCID: PMC9628328.
      Citations:    
    11. Wagner DL. The uncut version: base-edited allo-CAR T cells. Blood. 2022 08 11; 140(6):526-527. PMID: 35951345.
      Citations:    
    12. Wagner DL, Koehl U, Chmielewski M, Scheid C, Stripecke R. Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing. Front Immunol. 2022; 13:865424. PMID: 35784280; PMCID: PMC9248912.
      Citations:    
    13. Kath J, Du W, Pruene A, Braun T, Thommandru B, Turk R, Sturgeon ML, Kurgan GL, Amini L, Stein M, Zittel T, Martini S, Ostendorf L, Wilhelm A, Aky?z L, Rehm A, H?pken UE, Pru? A, K?nkele A, Jacobi AM, Volk HD, Schmueck-Henneresse M, Stripecke R, Reinke P, Wagner DL. Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T?cells. Mol Ther Methods Clin Dev. 2022 Jun 09; 25:311-330. PMID: 35573047; PMCID: PMC9062427.
      Citations:    
    14. Peter L, Wendering DJ, Schlickeiser S, Hoffmann H, Noster R, Wagner DL, Zarrinrad G, M?nch S, Picht S, Schulenberg S, Moradian H, Mashreghi MF, Klein O, Gossen M, Roch T, Babel N, Reinke P, Volk HD, Amini L, Schmueck-Henneresse M. Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients. Mol Ther Methods Clin Dev. 2022 Jun 09; 25:52-73. PMID: 35252469; PMCID: PMC8882037.
      Citations:    
    15. Wagner DL, Klotzsch E. Barring the gates to the battleground: DDR1 promotes immune exclusion in solid tumors. Signal Transduct Target Ther. 2022 01 13; 7(1):17. PMID: 35027528; PMCID: PMC8758727.
      Citations:    
    16. Pulsipher MA, Ahmed N, Hamieh M, Hegde M, Ruella M, Savoldo B, Shah NN, Turtle CJ, Wayne AS, Wagner DL, Fritsche E, Abou-El-Enein M. Immunogenicity of CAR T cells in cancer therapy. Nat Rev Clin Oncol. 2021 06; 18(6):379-393. PMID: 33633361; PMCID: PMC8923136.
      Citations: 32     Fields:    Translation:Humans
    17. Amini L, Greig J, Schmueck-Henneresse M, Volk HD, B?zie S, Reinke P, Guillonneau C, Wagner DL, Anegon I. Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications. Front Immunol. 2020; 11:611638. PMID: 33717052; PMCID: PMC7945682.
      Citations:    
    18. Wagner DL, Peter L, Schmueck-Henneresse M. Cas9-directed immune tolerance in humans-a model to evaluate regulatory T cells in gene therapy? Gene Ther. 2021 09; 28(9):549-559. PMID: 33574580; PMCID: PMC8455332.
      Citations:    
    19. Roemhild A, Otto NM, Moll G, Abou-El-Enein M, Kaiser D, Bold G, Schachtner T, Choi M, Oellinger R, Landwehr-Kenzel S, Juerchott K, Sawitzki B, Giesler C, Sefrin A, Beier C, Wagner DL, Schlickeiser S, Streitz M, Schmueck-Henneresse M, Amini L, Stervbo U, Babel N, Volk HD, Reinke P. Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial. BMJ. 2020 10 21; 371:m3734. PMID: 33087345; PMCID: PMC7576328.
      Citations:    
    20. Amini L, Wagner DL, R?ssler U, Zarrinrad G, Wagner LF, Vollmer T, Wendering DJ, Kornak U, Volk HD, Reinke P, Schmueck-Henneresse M. CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients. Mol Ther. 2021 01 06; 29(1):32-46. PMID: 32956624; PMCID: PMC7791012.
      Citations:    
    21. Toews K, Grunewald L, Schwiebert S, Klaus A, Winkler A, Ali S, Zirngibl F, Astrahantseff K, Wagner DL, Henssen AG, Deubzer HE, Schulte JH, Ochsenreither S, Eggert A, K?nkele A. Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells. Mol Carcinog. 2020 07; 59(7):724-735. PMID: 32333465.
      Citations:    
    22. Fousek K, Watanabe J, Joseph SK, George A, An X, Byrd TT, Morris JS, Luong A, Sanber K, Navai SA, Gad AZ, Salsman VS, Mathew PR, Kim HN, Wagner DL, Brunetti L, Jang A, Baker ML, Varadarajan N, Hegde M, Kim YM, Heisterkamp N, Abdel-Azim H, Ahmed N, Mart?nez-Paniagua MA. CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression. Leukemia. 2021 01; 35(1):75-89. PMID: 32205861; PMCID: PMC7519582.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    23. Bastian L, Schroeder MP, Eckert C, Schlee C, Tanchez JO, K?mpf S, Wagner DL, Schulze V, Isaakidis K, L?zaro-Navarro J, H?nzelmann S, James AR, Ekici A, Burmeister T, Schwartz S, Schrappe M, Horstmann M, Vosberg S, Krebs S, Blum H, Hecht J, Greif PA, Rieger MA, Br?ggemann M, G?kbuget N, Neumann M, Baldus CD. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia. Leukemia. 2019 08; 33(8):1895-1909. PMID: 30842609.
      Citations:    
    24. Wagner DL, Amini L, Wendering DJ, Burkhardt LM, Aky?z L, Reinke P, Volk HD, Schmueck-Henneresse M. High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population. Nat Med. 2019 02; 25(2):242-248. PMID: 30374197.
      Citations:    
    25. Shum T, Omer B, Tashiro H, Kruse RL, Wagner DL, Parikh K, Yi Z, Sauer T, Liu D, Parihar R, Castillo P, Liu H, Brenner MK, Metelitsa LS, Gottschalk S, Rooney CM. Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells. Cancer Discov. 2017 11; 7(11):1238-1247. PMID: 28830878; PMCID: PMC5669830.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    26. Gomes-Silva D, Srinivasan M, Sharma S, Lee CM, Wagner DL, Davis TH, Rouce RH, Bao G, Brenner MK, Mamonkin M. CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies. Blood. 2017 07 20; 130(3):285-296. PMID: 28539325; PMCID: PMC5520470.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    27. Gundry MC, Brunetti L, Lin A, Mayle AE, Kitano A, Hsu JI, Hoegenauer KA, Rooney CM, Goodell MA, Nakada D, Wagner D. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. Cell Rep. 2016 10 25; 17(5):1453-1461. PMID: 27783956; PMCID: PMC5087995.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    WAGNER's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (112)
    Explore
    _
    Co-Authors (16)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _