"Gene Editing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic engineering techniques that involve DNA REPAIR mechanisms for incorporating site-specific modifications into a cell's genome.
| Descriptor ID |
D000072669
|
| MeSH Number(s) |
E05.393.420.270
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Gene Editing".
Below are MeSH descriptors whose meaning is more specific than "Gene Editing".
This graph shows the total number of publications written about "Gene Editing" by people in this website by year, and whether "Gene Editing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2016 | 4 | 1 | 5 |
| 2017 | 6 | 1 | 7 |
| 2018 | 10 | 6 | 16 |
| 2019 | 5 | 6 | 11 |
| 2020 | 6 | 7 | 13 |
| 2021 | 5 | 9 | 14 |
| 2022 | 6 | 3 | 9 |
| 2023 | 5 | 0 | 5 |
| 2024 | 5 | 3 | 8 |
| 2025 | 2 | 2 | 4 |
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Below are the most recent publications written about "Gene Editing" by people in Profiles.
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In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. Sci Transl Med. 2025 Feb 12; 17(785):eadk3920.
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Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells. ACS Synth Biol. 2025 Feb 21; 14(2):384-397.
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Gene editing of CD3 epsilon to redirect regulatory T?cells for adoptive T?cell transfer. Mol Ther. 2025 Mar 05; 33(3):997-1013.
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Rat Models of Breast Cancer. Adv Exp Med Biol. 2025; 1464:123-148.
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Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene. Bone Res. 2024 Dec 06; 12(1):70.
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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines. Sci Rep. 2024 09 30; 14(1):22626.
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Simulation of CRISPR-Cas9 editing on evolving barcode and accuracy of lineage tracing. Sci Rep. 2024 08 19; 14(1):19213.
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Emerging therapies in hereditary ataxias. Trends Mol Med. 2025 Feb; 31(2):181-194.
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Integration of ?-deficient CARs into the CD3? gene conveys potent cytotoxicity in T and NK cells. Blood. 2024 06 20; 143(25):2599-2611.
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Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024 Jun; 163:104252.