"Gene Editing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic engineering techniques that involve DNA REPAIR mechanisms for incorporating site-specific modifications into a cell's genome.
| Descriptor ID |
D000072669
|
| MeSH Number(s) |
E05.393.420.270
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Gene Editing".
Below are MeSH descriptors whose meaning is more specific than "Gene Editing".
This graph shows the total number of publications written about "Gene Editing" by people in this website by year, and whether "Gene Editing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 4 | 1 | 5 |
| 2017 | 8 | 2 | 10 |
| 2018 | 11 | 7 | 18 |
| 2019 | 8 | 10 | 18 |
| 2020 | 5 | 6 | 11 |
| 2021 | 9 | 10 | 19 |
| 2022 | 9 | 5 | 14 |
| 2023 | 5 | 5 | 10 |
| 2024 | 7 | 3 | 10 |
| 2025 | 9 | 6 | 15 |
| 2026 | 6 | 3 | 9 |
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Below are the most recent publications written about "Gene Editing" by people in Profiles.
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In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. Sci Transl Med. 2025 02 12; 17(785):eadk3920.
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An oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing. Genesis. 2024 04; 62(2):e23589.
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Engineered PROTAC-CID Systems for Mammalian Inducible Gene Regulation. J Am Chem Soc. 2023 01 25; 145(3):1593-1606.
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Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. Int J Biochem Cell Biol. 2018 12; 105:134-143.
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Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles. BMC Biol. 2018 Jun 21; 16(1):69.
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Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing. Stem Cell Res. 2018 05; 29:215-219.
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A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing. Stem Cell Res. 2018 03; 27:131-135.
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Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling. Mol Cell Proteomics. 2017 04; 16(4):594-607.
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Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. Cell Rep. 2016 10 25; 17(5):1453-1461.