"Paraproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
| Descriptor ID |
D010266
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| MeSH Number(s) |
D12.776.124.486.485.900 D12.776.124.790.651.900 D12.776.377.715.548.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paraproteins".
Below are MeSH descriptors whose meaning is more specific than "Paraproteins".
This graph shows the total number of publications written about "Paraproteins" by people in this website by year, and whether "Paraproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Paraproteins" by people in Profiles.
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Solitary plasmacytomas: outcome and prognostic factors after definitive radiation therapy. Cancer. 2011 Oct 01; 117(19):4468-74.
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Lymphoplasmacytic lymphoma/waldenstrom macroglobulinemia: an evolving concept. Adv Anat Pathol. 2005 Sep; 12(5):246-55.
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Chronic lymphocytic leukemia/small lymphocytic lymphoma associated with IgM paraprotein. Am J Clin Pathol. 2005 Apr; 123(4):594-602.
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Lymphoid neoplasms associated with IgM paraprotein: a study of 382 patients. Am J Clin Pathol. 2005 Feb; 123(2):200-5.
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Measurement of beta1- and beta2-globulins improves detection of M-spikes on high-resolution electrophoresis. Clin Chem. 2003 Apr; 49(4):676-8.