Lymphoma, Large B-Cell, Diffuse
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Lymphoma, Large B-Cell, Diffuse" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D016403
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						| MeSH Number(s) | 
						
							 C04.557.386.480.150.585 C15.604.515.569.480.150.585 C20.683.515.761.480.150.585 
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						| Concept/Terms | 
						
							Lymphoma, Large B-Cell, Diffuse- Lymphoma, Large B-Cell, Diffuse
 - Diffuse, Large B-Cell, Lymphoma
 - Histiocytic Lymphoma
 - Histiocytic Lymphomas
 - Lymphomas, Histiocytic
 - Histiocytic Lymphoma, Diffuse
 - Diffuse Histiocytic Lymphoma
 - Diffuse Histiocytic Lymphomas
 - Histiocytic Lymphomas, Diffuse
 - Lymphoma, Diffuse Histiocytic
 - Lymphomas, Diffuse Histiocytic
 - Large Lymphoid Lymphoma, Diffuse
 - Lymphoma, Large-Cell, Diffuse
 - Lymphoma, Diffuse Large-Cell
 - Lymphoma, Diffuse Large Cell
 - Lymphoma, Histiocytic
 - Lymphoma, Large Lymphoid, Diffuse
 - Lymphoma, Histiocytic, Diffuse
 - Lymphoma, Large Cell, Diffuse
 - Diffuse Large-Cell Lymphoma
 - Diffuse Large Cell Lymphoma
 - Diffuse Large-Cell Lymphomas
 - Large-Cell Lymphomas, Diffuse
 - Lymphomas, Diffuse Large-Cell
 - Large-Cell Lymphoma, Diffuse
 - Large Cell Lymphoma, Diffuse
 
  
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				Below are MeSH descriptors whose meaning is more general than "Lymphoma, Large B-Cell, Diffuse".
				
					
						- Diseases [C]
 - Neoplasms [C04]
 - Neoplasms by Histologic Type [C04.557]
 - Lymphoma [C04.557.386]
 - Lymphoma, Non-Hodgkin [C04.557.386.480]
 - Lymphoma, B-Cell [C04.557.386.480.150]
 - Lymphoma, Large B-Cell, Diffuse [C04.557.386.480.150.585]
 - Hemic and Lymphatic Diseases [C15]
 - Lymphatic Diseases [C15.604]
 - Lymphoproliferative Disorders [C15.604.515]
 - Lymphoma [C15.604.515.569]
 - Lymphoma, Non-Hodgkin [C15.604.515.569.480]
 - Lymphoma, B-Cell [C15.604.515.569.480.150]
 - Lymphoma, Large B-Cell, Diffuse [C15.604.515.569.480.150.585]
 - Immune System Diseases [C20]
 - Immunoproliferative Disorders [C20.683]
 - Lymphoproliferative Disorders [C20.683.515]
 - Lymphoma [C20.683.515.761]
 - Lymphoma, Non-Hodgkin [C20.683.515.761.480]
 - Lymphoma, B-Cell [C20.683.515.761.480.150]
 - Lymphoma, Large B-Cell, Diffuse [C20.683.515.761.480.150.585]
 
					
				 
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Lymphoma, Large B-Cell, Diffuse".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Lymphoma, Large B-Cell, Diffuse" by people in this website by year, and whether "Lymphoma, Large B-Cell, Diffuse" was a major or minor topic of these publications. 
				
					
                    To see the data from this visualization as text, 
click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1996 | 1 | 1 | 2 | 
| 1997 | 2 | 0 | 2 | 
| 1998 | 1 | 0 | 1 | 
| 2002 | 3 | 1 | 4 | 
| 2003 | 2 | 0 | 2 | 
| 2004 | 0 | 1 | 1 | 
| 2005 | 1 | 0 | 1 | 
| 2006 | 3 | 0 | 3 | 
| 2008 | 1 | 0 | 1 | 
| 2009 | 2 | 0 | 2 | 
| 2010 | 3 | 0 | 3 | 
| 2011 | 6 | 1 | 7 | 
| 2012 | 4 | 0 | 4 | 
| 2013 | 4 | 0 | 4 | 
| 2014 | 6 | 0 | 6 | 
| 2015 | 6 | 2 | 8 | 
| 2016 | 9 | 1 | 10 | 
| 2017 | 3 | 1 | 4 | 
| 2018 | 4 | 0 | 4 | 
| 2019 | 4 | 0 | 4 | 
| 2020 | 8 | 0 | 8 | 
| 2021 | 6 | 1 | 7 | 
| 2022 | 11 | 0 | 11 | 
| 2023 | 7 | 0 | 7 | 
| 2024 | 7 | 3 | 10 | 
| 2025 | 9 | 0 | 9 | 
                    To return to the timeline, 
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				Below are the most recent publications written about "Lymphoma, Large B-Cell, Diffuse" by people in Profiles.
						
					
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Infection after CD19 chimeric antigen receptor T-cell therapy for large B-cell lymphoma: real-world analysis from CIBMTR. Blood Adv. 2025 Nov 11; 9(21):5460-5472.
															
								 
							
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Large B cell lymphoma microenvironment archetype profiles. Cancer Cell. 2025 Jul 14; 43(7):1347-1364.e13.
															
								 
							
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Real-world healthcare costs for patients treated with chimeric antigen receptor T-cell therapy in Canada. Leuk Lymphoma. 2025 Oct; 66(10):1875-1883.
															
								 
							
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Hematology-oncology provider perspectives regarding lymphoma treatment and cardioprotective strategies in patients with lymphoma at high risk for heart failure. Leuk Lymphoma. 2025 Aug; 66(8):1437-1446.
															
								 
							
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Odronextamab monotherapy in R/R DLBCL after progression with CAR T-cell therapy: primary analysis of the ELM-1 study. Blood. 2025 Apr 03; 145(14):1498-1509.
															
								 
							
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Odronextamab monotherapy in patients with relapsed/refractory diffuse large B cell lymphoma: primary efficacy and safety analysis in phase 2 ELM-2 trial. Nat Cancer. 2025 Mar; 6(3):528-539.
															
								 
							
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Real-world comparison of lisocabtagene maraleucel and axicabtagene ciloleucel in large B-cell lymphoma: an inverse probability of treatment weighting analysis with 3-year follow-up. Haematologica. 2025 Sep 01; 110(9):2040-2054.
															
								 
							
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Lisocabtagene maraleucel for relapsed/refractory large B-cell lymphoma: a cell therapy consortium real-world analysis. Blood Adv. 2025 Mar 11; 9(5):1232-1241.
															
								 
							
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Loncastuximab in high-risk and heavily pretreated relapsed/refractory diffuse large B-cell lymphoma: a realworld analysis from 21 US centers. Haematologica. 2025 Mar 01; 110(3):706-714.
															
								 
							
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MGMT epimutations and risk of incident cancer of the colon, glioblastoma multiforme, and diffuse large B cell lymphomas. Clin Epigenetics. 2025 Feb 20; 17(1):28.