"Pyrimidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
Descriptor ID |
D011743
|
MeSH Number(s) |
D03.383.742
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrimidines".
Below are MeSH descriptors whose meaning is more specific than "Pyrimidines".
This graph shows the total number of publications written about "Pyrimidines" by people in this website by year, and whether "Pyrimidines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
1998 | 3 | 1 | 4 |
1999 | 0 | 1 | 1 |
2000 | 2 | 0 | 2 |
2001 | 6 | 4 | 10 |
2002 | 18 | 3 | 21 |
2003 | 48 | 12 | 60 |
2004 | 39 | 16 | 55 |
2005 | 30 | 14 | 44 |
2006 | 41 | 17 | 58 |
2007 | 56 | 37 | 93 |
2008 | 53 | 29 | 82 |
2009 | 66 | 23 | 89 |
2010 | 65 | 28 | 93 |
2011 | 55 | 35 | 90 |
2012 | 46 | 39 | 85 |
2013 | 47 | 41 | 88 |
2014 | 38 | 24 | 62 |
2015 | 41 | 37 | 78 |
2016 | 41 | 34 | 75 |
2017 | 42 | 39 | 81 |
2018 | 43 | 37 | 80 |
2019 | 36 | 38 | 74 |
2020 | 23 | 29 | 52 |
2021 | 30 | 22 | 52 |
2022 | 5 | 32 | 37 |
2023 | 4 | 13 | 17 |
2024 | 5 | 1 | 6 |
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Below are the most recent publications written about "Pyrimidines" by people in Profiles.
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Clinical outcomes of patients with myelofibrosis after immediate transition to momelotinib from ruxolitinib. Haematologica. 2024 Feb 01; 109(2):676-681.
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TBCRC 039: a phase II study of preoperative ruxolitinib with or without paclitaxel for triple-negative inflammatory breast cancer. Breast Cancer Res. 2024 01 31; 26(1):20.
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Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Cell Death Dis. 2024 01 22; 15(1):80.
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Cost Effectiveness of Zanubrutinib Versus Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia. Pharmacoeconomics. 2024 Apr; 42(4):409-418.
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Sotorasib with panitumumab in chemotherapy-refractory KRASG12C-mutated colorectal cancer: a phase 1b trial. Nat Med. 2024 Jan; 30(1):265-270.
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Pralsetinib in Patients with Advanced/Metastatic Rearranged During Transfection (RET)-Altered Thyroid Cancer: Updated Efficacy and Safety Data from the ARROW Study. Thyroid. 2024 01; 34(1):26-40.
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Long-term benefit of sotorasib in patients with KRAS G12C-mutated non-small-cell lung cancer: plain language summary. Future Oncol. 2024 Jan; 20(3):113-120.
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Real-World Efficacy and Safety of Amivantamab for EGFR-Mutant NSCLC. J Thorac Oncol. 2024 Mar; 19(3):500-506.
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Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer. Sci Rep. 2023 11 18; 13(1):20223.
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Pralsetinib in patients with RET fusion-positive non-small-cell lung cancer: A plain language summary of the ARROW study. Future Oncol. 2024 Feb; 20(6):297-306.