"Pyrithiamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency.
| Descriptor ID |
D011745
|
| MeSH Number(s) |
D03.383.725.762.760 D03.383.742.715
|
| Concept/Terms |
Pyrithiamine- Pyrithiamine
- Heterovitamin B 1
- 1, Heterovitamin B
- B 1, Heterovitamin
- Neopyrithiamine
|
Below are MeSH descriptors whose meaning is more general than "Pyrithiamine".
Below are MeSH descriptors whose meaning is more specific than "Pyrithiamine".
This graph shows the total number of publications written about "Pyrithiamine" by people in this website by year, and whether "Pyrithiamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrithiamine" by people in Profiles.
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Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions. J Neuropathol Exp Neurol. 1995 Mar; 54(2):255-67.
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Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy. J Neurosci Res. 1994 Aug 01; 38(5):565-74.
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Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801. J Neurochem. 1993 Dec; 61(6):2175-82.