"Immunoglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
| Descriptor ID |
D007136
|
| MeSH Number(s) |
D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548
|
| Concept/Terms |
Immunoglobulins- Immunoglobulins
- Immunoglobulin
- Globulins, Immune
- Immune Globulins
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulins".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins".
This graph shows the total number of publications written about "Immunoglobulins" by people in this website by year, and whether "Immunoglobulins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 0 | 3 | 3 |
| 1996 | 2 | 3 | 5 |
| 1997 | 3 | 1 | 4 |
| 1998 | 2 | 4 | 6 |
| 1999 | 2 | 2 | 4 |
| 2000 | 0 | 3 | 3 |
| 2001 | 4 | 2 | 6 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 4 | 2 | 6 |
| 2005 | 2 | 3 | 5 |
| 2006 | 3 | 2 | 5 |
| 2007 | 1 | 4 | 5 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 5 | 6 |
| 2010 | 1 | 5 | 6 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 0 | 3 | 3 |
| 2015 | 4 | 2 | 6 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 5 | 7 |
| 2020 | 4 | 2 | 6 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 5 | 6 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Immunoglobulins" by people in Profiles.
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Immunoglobulins act as predictors of chronicity in pediatric immune thrombocytopenia. Blood Adv. 2024 10 08; 8(19):5118-5121.
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Novel SAMD9 Variant Causing MIRAGE Syndrome Treated with Subcutaneous Immunoglobulin. J Clin Immunol. 2024 09 30; 45(1):19.
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SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion. Oncoimmunology. 2024; 13(1):2376264.
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Immunoglobulin High Throughput Sequencing (Ig-HTS) Minimal Residual Disease (MRD) Analysis is an Effective Surveillance Tool in Patients With Mantle Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2024 04; 24(4):254-259.
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Tumor-Infiltrating Normal B Cells Revealed by Immunoglobulin Repertoire Clonotype Analysis Are Highly Prognostic and Crucial for Antitumor Immune Responses in DLBCL. Clin Cancer Res. 2023 12 01; 29(23):4808-4821.
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Antibody neutralisation of emerging SARS-CoV-2 subvariants: EG.5.1 and XBC.1.6. Lancet Infect Dis. 2023 10; 23(10):e397-e398.
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In-vivo and human evidence for potential efficacy of therapeutic polyclonal RSV neutralizing antibodies for palivizumab-resistant RSV infections. Virology. 2023 09; 586:115-121.
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CancerHERVdb: Human Endogenous Retrovirus (HERV) Expression Database for Human Cancer Accelerates Studies of the Retrovirome and Predictions for HERV-Based Therapies. J Virol. 2023 06 29; 97(6):e0005923.
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Prognostic impact of pretreatment immunoglobulin clonal composition in pediatric B-lymphoblastic leukemia. Haematologica. 2023 03 01; 108(3):900-904.
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Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation. Neuron. 2023 03 01; 111(5):682-695.e9.