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JAMES CROWE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Radiology
Address6621 FANNIN
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    Collapse Research 
    Collapse research activities and funding
    R01AI141661     (BUKREYEV, ALEXANDER)Nov 1, 2018 - Oct 31, 2023
    NIH/NIAID
    Epitope-Based Design and Modified RNA Platform for Bivalent Marburgvirus Vaccine
    Role: Co-Principal Investigator
    R01AI127828     (CROWE, JAMES E)Jan 1, 2017 - Dec 31, 2021
    NIH/NIAID
    Human neutralizing antibodies for Zika virus
    Role: Principal Investigator
    U19AI117905     (CROWE, JAMES E)May 1, 2015 - Apr 30, 2020
    NIH/NIAID
    Structure based design of antibodies and vaccines
    Role: Principal Investigator
    R01AI114816     (CROWE, JAMES E)Feb 10, 2015 - Jan 31, 2020
    NIH/NIAID
    Structural and functional basis of ultra potent CHKV neutralization by human mAbs
    Role: Principal Investigator
    R56AI110750     (MEILER, JENS)Sep 5, 2014 - Aug 31, 2015
    NIH/NIAID
    Hybrid Methods for Prediction and Design of Novel Human Influenza Antibodies
    Role: Co-Principal Investigator
    R21AI103834     (CROWE, JAMES E)Jun 1, 2013 - May 31, 2015
    NIH/NIAID
    Human neutralizing monoclonal antibodies for Rift Valley fever virus
    Role: Principal Investigator
    R01AI106002     (CROWE, JAMES E)Aug 15, 2012 - Jul 31, 2016
    NIH/NIAID
    Molecular Determinants of Cross-Reactive Antibody Response to Influenza in Humans
    Role: Principal Investigator
    T32AI089554     (CROWE, JAMES E)May 1, 2010 - Apr 30, 2015
    NIH/NIAID
    Virology Training Program
    Role: Principal Investigator
    S10RR027977     (CROWE, JAMES E)Mar 4, 2010 - Mar 3, 2011
    NIH/NCRR
    Multi-Laser Flow Cytometer for Polychromatic Analysis
    Role: Principal Investigator
    R21AI083574     (CROWE, JAMES E)Jul 22, 2009 - Jun 30, 2011
    NIH/NIAID
    Rotavirus VP6 Specific Human IgA Antibodies
    Role: Principal Investigator
    U01AI078407     (CROWE, JAMES E)Mar 15, 2008 - Feb 28, 2013
    NIH/NIAID
    Clonal Analysis of the Human B Cell Response to HIV
    Role: Principal Investigator
    R21AG030321     (CROWE, JAMES E)Sep 30, 2007 - Jul 31, 2010
    NIH/NIA
    Respiratory Syncytial Virus Nanoparticle Vaccines
    Role: Principal Investigator
    PN1EY016567     (CROWE, JAMES E)Sep 30, 2004 - Jul 31, 2005
    NIH/NEI
    Immunomodulation on the Nanoscale (RMI)
    Role: Principal Investigator
    R01AI057933     (CROWE, JAMES E)Jun 15, 2004 - May 31, 2009
    NIH/NIAID
    Human Antibody Responses to Rotavirus
    Role: Principal Investigator
    R01AI059597     (CROWE, JAMES E)Apr 1, 2004 - Feb 28, 2010
    NIH/NIAID
    Alphavirus-based Vaccine for Prevention of MPV Infection
    Role: Principal Investigator
    S10RR019032     (CROWE, JAMES E)Apr 1, 2004 - Mar 31, 2005
    NIH/NCRR
    High Throughput Flow Cytometry Sorter
    Role: Principal Investigator
    R01AI057661     (CROWE, JAMES E)Sep 15, 2003 - Feb 28, 2008
    NIH/NIAID
    Cell-Mediated Immune Responses to Vaccinia Viruses
    Role: Principal Investigator
    R01AI053222     (CROWE, JAMES E)Jul 1, 2003 - Jun 30, 2007
    NIH/NIAID
    Human T Cells Responses to RSV
    Role: Principal Investigator
    R01AI048677     (CROWE, JAMES E)Sep 1, 2002 - Aug 31, 2006
    NIH/NIAID
    Novel methods for generation of human B cell hybridomas
    Role: Principal Investigator
    R03TW001497     (CROWE, JAMES E)Aug 15, 2002 - Jun 30, 2005
    NIH/FIC
    Epitope Specificity of RSV Nucleoprotein-Specific T Cel*
    Role: Principal Investigator
    U01AI048512     (CROWE, JAMES E)Sep 15, 2000 - Aug 31, 2003
    NIH/NIAID
    HUMAN MONOCLONAL ANTIBODIES THAT NEUTRALIZE VACCINIA
    Role: Principal Investigator
    R21DE014039     (CROWE, JAMES E)Sep 1, 2000 - Aug 31, 2003
    NIH/NIDCR
    RESPIRATORY VIRUS NEUTRALIZATION BY INTRACELLULAR AB
    Role: Principal Investigator
    R01HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2003
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator
    R29HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2002
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Le?n AN, Rodriguez AJ, Richey ST, Torrents de la Pena A, Wolters RM, Jackson AM, Webb K, Creech CB, Yoder S, Mudd PA, Crowe JE, Han J, Ward AB. Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection. mBio. 2025 Feb 06; e0203024. PMID: 39912630.
      Citations:    Fields:    
    2. Jamieson PJ, Shen X, Abu-Shmais AA, Wasdin PT, Janowska K, Edwards RJ, Scapellato G, Richardson SI, Manamela NP, Liu S, Barr M, Gillespie RA, Mimms J, Suryadevara N, Sornberger TA, Zost S, Parks R, Flaherty S, Janke AK, Howard BN, Suresh YP, Ruprecht RM, Crowe JE, Carnahan RH, Bailey JR, Masaru K, Haynes BF, Moore PL, Acharya P, Montefiori DC, Kalams SA, Lu S, Georgiev IS, Jamieson PJ, Shen X, Abu-Shmais AA, Wasdin PT, Janowska K, Edwards RJ, Scapellato G, Richardson SI, Manamela NP, Liu S, Barr M, Gillespie RA, Mimms J, Suryadevara N, Sornberger TA, Zost S, Parks R, Flaherty S, Janke AK, Howard BN, Suresh YP, Ruprecht RM, Crowe JE, Carnahan RH, Bailey JR, Masaru K, Haynes BF, Moore PL, Acharya P, Montefiori DC, Kalams SA, Lu S, Georgiev IS. Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity. bioRxiv. 2025 Jan 20. PMID: 39896680; PMCID: PMC11785028.
      Citations:    
    3. Langel SN, Otero CE, Steppe JT, Williams CA, Travieso T, Chang J, Webster H, Williamson LE, Crowe JE, Greenberg HB, Wu H, Hornik CP, Mansouri K, Edwards RJ, Stalls V, Acharya P, Blasi M, Permar SR. Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus. Mucosal Immunol. 2025 Jan 20. PMID: 39842610.
      Citations:    Fields:    
    4. Shenoi RP, Crowe JE, Dorfman SR, Bergmann KR, Mistry RD, Hariharan S, Tavarez MM, Wai S, Jones JL, Langhan ML, Ward CE, McCallin TE, Sethuraman U, Shah N, Mendez D, Wolpert KH, Santos-Malave C, Ruttan T, Quayle KS, Okada P, Bubolz B, Buscher JF, McKee R, Mangold K, Wendt WJ, Thompson AD, Hom J, Brayer AF, Blackstone MM, Brennan C, Russell WS, Agarwal M, Khanna K, Louie J, Sheridan D, Camp EA, Pediatric Emergency Medicine Collaborative Research Committee, Shenoi RP, Bergmann KR, Mistry RD, Hariharan S, Tavarez MM, Wai S, Jones JL, Langhan ML, Ward CE, McCallin TE, Sethuraman U, Shah N, Mendez D, Wolpert KH, Santos-Malave C, Ruttan T, Quayle KS, Okada P, Bubolz B, Buscher JF, McKee R, Mangold K, Wendt WJ, Thompson AD, Hom J, Brayer AF, Blackstone MM, Brennan C, Russell WS, Agarwal M, Khanna K, Louie J, Sheridan D, Camp EA. Factors Associated with Pediatric Drowning-Associated Lung Injury. J Pediatr. 2024 Dec 28; 279:114459. PMID: 39736377.
      Citations:    Fields:    
    5. Verhoeven D, Sponseller BA, Crowe JE, Bangaru S, Webby RJ, Lee BM. Use of equine H3N8 hemagglutinin as a broadly protective influenza vaccine immunogen. NPJ Vaccines. 2024 Dec 19; 9(1):247. PMID: 39702334; PMCID: PMC11659547.
      Citations:    
    6. Suryadevara N, Kose N, Bangaru S, Binshtein E, Munt J, Martinez DR, Sch?fer A, Myers L, Scobey TD, Carnahan RH, Ward AB, Baric RS, Crowe JE, Suryadevara N, Kose N, Bangaru S, Binshtein E, Munt J, Martinez DR, Sch?fer A, Myers L, Scobey TD, Carnahan RH, Ward AB, Baric RS, Crowe JE. Structural characterization of human monoclonal antibodies targeting uncommon antigenic sites on spike glycoprotein of SARS-CoV. J Clin Invest. 2024 Nov 26; 135(3). PMID: 39589795; PMCID: PMC11785922.
      Citations:    Fields:    
    7. Nkolola JP, Hope D, Guan R, Colarusso A, Aid M, Weiss D, Misamore J, Andersen H, Lewis MG, Williamson L, Carnahan RH, Crowe JE, Barouch DH. Protective threshold of a potent neutralizing Zika virus monoclonal antibody in rhesus macaques. J Virol. 2024 Dec 17; 98(12):e0142924. PMID: 39545728; PMCID: PMC11650990.
      Citations:    Fields:    Translation:HumansAnimalsCells
    8. Abu-Shmais AA, Guo L, Khalil AM, Miller RJ, Janke AK, Vukovich MJ, Bass LE, Suresh YP, Rush SA, Wolters RM, Kose N, Carnahan RH, Crowe JE, Bonami RH, Mousa JJ, McLellan JS, Georgiev IS, Abu-Shmais AA, Guo L, Khalil AM, Miller RJ, Janke AK, Vukovich MJ, Bass LE, Suresh YP, Rush SA, Wolters RM, Kose N, Carnahan RH, Crowe JE, Bonami RH, Mousa JJ, McLellan JS, Georgiev IS. A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein. bioRxiv. 2024 Nov 01. PMID: 39554078; PMCID: PMC11565947.
      Citations:    
    9. Cabel CR, Guzman BA, Alizadeh E, Li S, Holberg C, Wichaidit C, Cusanovich DA, Paek AL, Thatcher GRJ, Doorslaer KV, Nargi RS, Sutton RE, Suryadevara N, Crowe JE, Carnahan RH, Campos SK, Thorne CA. Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors. bioRxiv. 2024 Oct 07. PMID: 39416139; PMCID: PMC11483034.
      Citations:    
    10. Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson SI, Manamela NP, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe JE, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS. Discovery and characterization of a pan-betacoronavirus S2-binding antibody. Structure. 2024 Nov 07; 32(11):1893-1909.e11. PMID: 39326419; PMCID: PMC11560675.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    11. Connors KA, Chapman NS, McMillen CM, Hoehl RM, McGaughey JJ, Frey ZD, Midgett M, Williams C, Reed DS, Crowe JE, Hartman AL, Connors KA, Chapman NS, McMillen CM, Hoehl RM, McGaughey JJ, Frey ZD, Midgett M, Williams C, Reed DS, Crowe JE, Hartman AL. Potent neutralizing human monoclonal antibodies protect from Rift Valley fever encephalitis. JCI Insight. 2024 Aug 01; 9(18). PMID: 39088277; PMCID: PMC11457859.
      Citations:    Fields:    
    12. Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE, Bukreyev A. Author Correction: Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement system. Commun Biol. 2024 Jul 31; 7(1):921. PMID: 39085489; PMCID: PMC11291504.
      Citations:    
    13. Kuzmin IV, Soto Acosta R, Pruitt L, Wasdin PT, Kedarinath K, Hernandez KR, Gonzales KA, Hill K, Weidner NG, Mire C, Engdahl TB, Moon WJ, Popov V, Crowe JE, Georgiev IS, Garcia-Blanco MA, Abbott RK, Bukreyev A. Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine. Nat Commun. 2024 Jul 30; 15(1):6421. PMID: 39080316; PMCID: PMC11289437.
      Citations:    Fields:    Translation:HumansAnimalsCells
    14. Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE, Bukreyev A. Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement system Commun Biol. 2024 07 17; 7(1):871. PMID: 39020082; PMCID: PMC11255267.
      Citations: 2     Translation:HumansAnimalsCells
    15. Le?n AN, Rodriguez AJ, Richey ST, Torrents de la Pe?a A, Wolters RM, Jackson AM, Webb K, Creech CB, Yoder S, Mudd PA, Crowe JE, Han J, Ward AB, Le?n AN, Rodriguez AJ, Richey ST, de la Pe?a AT, Wolters RM, Jackson AM, Webb K, Creech CB, Yoder S, Mudd PA, Crowe JE, Han J, Ward AB. Structural Mapping of Polyclonal IgG Responses to HA After Influenza Virus Vaccination or Infection. bioRxiv. 2024 Jul 11. PMID: 39026813; PMCID: PMC11257458.
      Citations:    
    16. Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe JE. Functional and structural basis of human parainfluenza virus type 3 neutralization with human monoclonal antibodies. Nat Microbiol. 2024 Aug; 9(8):2128-2143. PMID: 38858594.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Wolters RM, Ferguson JA, Nu?ez IA, Chen EE, Sornberger T, Myers L, Oeverdieck S, Raghavan SSR, Kona C, Handal LS, Esilu TE, Davidson E, Doranz BJ, Engdahl TB, Kose N, Williamson LE, Creech CB, Gibson-Corley KN, Ward AB, Crowe JE. Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface. Immunity. 2024 06 11; 57(6):1413-1427.e9. PMID: 38823390; PMCID: PMC11440431.
      Citations:    Fields:    
    18. Liang CY, Raju S, Liu Z, Li Y, Asthagiri Arunkumar G, Case JB, Scheaffer SM, Zost SJ, Acreman CM, Gagne M, Andrew SF, Carvalho Dos Anjos DC, Foulds KE, McLellan JS, Crowe JE, Douek DC, Whelan SPJ, Elbashir SM, Edwards DK, Diamond MS. Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines. Nature. 2024 Jun; 630(8018):950-960. PMID: 38749479; PMCID: PMC11419699.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    19. Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Tri-lab COVID-19 Consortium, Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe JE, Carnahan RH, Faissol DM. Computationally restoring the potency of a clinical antibody against Omicron. Nature. 2024 May; 629(8013):878-885. PMID: 38720086; PMCID: PMC11111397.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    20. Abu-Shmais AA, Miller RJ, Janke AK, Wolters RM, Holt CM, Raju N, Carnahan RH, Crowe JE, Mousa JJ, Georgiev IS. Potent HPIV3-neutralizing IGHV5-51 Antibodies Identified from Multiple Individuals Show L Chain and CDRH3 Promiscuity. J Immunol. 2024 May 01; 212(9):1450-1456. PMID: 38488511; PMCID: PMC11018509.
      Citations: 1     Fields:    
    21. Larsen BB, McMahon T, Brown JT, Wang Z, Radford CE, Crowe JE, Veesler D, Bloom JD. Functional and antigenic landscape of the Nipah virus receptor binding protein. bioRxiv. 2024 Apr 19. PMID: 38659959; PMCID: PMC11042328.
      Citations:    
    22. Zeitlin L, Cross RW, Woolsey C, West BR, Borisevich V, Agans KN, Prasad AN, Deer DJ, Stuart L, McCavitt-Malvido M, Kim DH, Pettitt J, Crowe JE, Whaley KJ, Veesler D, Dimitrov A, Abelson DM, Geisbert TW, Broder CC. Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates. Sci Transl Med. 2024 Apr 03; 16(741):eadl2055. PMID: 38569014.
      Citations: 3     Fields:    Translation:AnimalsCells
    23. Bukreyev A, Meyer M, Gunn B, Pietzsch C, Subramani C, Saphire E, Crowe J, Alter G, Himansu S, Carfi A. Divergent antibody recognition profiles are generated by protective mRNA vaccines against Marburg and Ravn viruses. Res Sq. 2024 Mar 26. PMID: 38585993; PMCID: PMC10996797.
      Citations:    
    24. Hauck J, Gerard A, Crowe JE, Martinez CA, Machol K. Transient Generalized Osteosclerosis in a Newborn Mimicking Congenital Osteopetrosis with Negative Comprehensive Genetic Workup: A Case Report. J Pediatr Clin Pract. 2024 Mar; 11:200100. PMID: 38827482; PMCID: PMC11138251.
      Citations:    
    25. Emery A, Moore S, Crowe J, Murray J, Peacock O, Thompson D, Betts F, Rapps S, Ross L, Rothschild-Rodriguez D, Arana Echarri A, Davies R, Lewis R, Augustine DX, Whiteway A, Afzal Z, Heaney J, Drayson MT, Turner JE, Campbell JP. The effects of short-term, progressive exercise training on disease activity in smouldering multiple myeloma and monoclonal gammopathy of undetermined significance: a single-arm pilot study. BMC Cancer. 2024 Feb 05; 24(1):174. PMID: 38317104; PMCID: PMC10840198.
      Citations: 2     Fields:    Translation:Humans
    26. Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson S, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe JE, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS. Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody. bioRxiv. 2024 Jan 16. PMID: 38293237; PMCID: PMC10827111.
      Citations:    
    27. Adams LJ, VanBlargan LA, Liu Z, Gilchuk P, Zhao H, Chen RE, Raju S, Chong Z, Whitener BM, Shrihari S, Jethva PN, Gross ML, Crowe JE, Whelan SPJ, Diamond MS, Fremont DH. A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection. Cell Rep Med. 2023 12 19; 4(12):101305. PMID: 38039973; PMCID: PMC10772349.
      Citations:    Fields:    Translation:AnimalsCells
    28. Wall SC, Suryadevara N, Kim C, Shiakolas AR, Holt CM, Irbe EB, Wasdin PT, Suresh YP, Binshtein E, Chen EC, Zost SJ, Canfield E, Crowe JE, Thompson-Arildsen MA, Sheward DJ, Carnahan RH, Georgiev IS. SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes. Cell Rep Med. 2023 11 21; 4(11):101267. PMID: 37935199; PMCID: PMC10694659.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    29. Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE, Van Rompay KKA, Lovalenti P, Forthal DN, Haigwood NL. Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology. Nat Commun. 2023 11 03; 14(1):7062. PMID: 37923717; PMCID: PMC10624670.
      Citations:    Fields:    Translation:HumansAnimalsCells
    30. Munt JE, Henein S, Adams C, Young E, Hou YJ, Conrad H, Zhu D, Dong S, Kose N, Yount B, Meganck RM, Tse LPV, Kuan G, Balmaseda A, Ricciardi MJ, Watkins DI, Crowe JE, Harris E, DeSilva AM, Baric RS. Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination. Cell Host Microbe. 2023 11 08; 31(11):1850-1865.e5. PMID: 37909048; PMCID: PMC11221912.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    31. Powers AM, Williamson LE, Carnahan RH, Crowe JE, Hyde JL, Jonsson CB, Nasar F, Weaver SC. Developing a Prototype Pathogen Plan and Research Priorities for the Alphaviruses. J Infect Dis. 2023 10 18; 228(Suppl 6):S414-S426. PMID: 37849399; PMCID: PMC11007399.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    32. Santos RI, Ilinykh PA, Pietzsch CA, Ronk AJ, Huang K, Kuzmina NA, Zhou F, Crowe JE, Bukreyev A. Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin. Cell Rep. 2023 10 31; 42(10):113254. PMID: 37858466; PMCID: PMC10664807.
      Citations:    Fields:    Translation:HumansCells
    33. Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Sch?fer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE, Kawaoka Y, Baric RS. Host range, transmissibility and antigenicity of a pangolin coronavirus. Nat Microbiol. 2023 10; 8(10):1820-1833. PMID: 37749254; PMCID: PMC10522490.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    34. Chapman NS, Hulswit RJG, Westover JLB, Stass R, Paesen GC, Binshtein E, Reidy JX, Engdahl TB, Handal LS, Flores A, Gowen BB, Bowden TA, Crowe JE. Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses. Nat Commun. 2023 09 13; 14(1):5650. PMID: 37704627; PMCID: PMC10499838.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    35. Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe JE. Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode. Cell Host Microbe. 2023 08 09; 31(8):1288-1300.e6. PMID: 37516111; PMCID: PMC10527986.
      Citations: 1     Fields:    Translation:HumansCells
    36. McMillen CM, Chapman NS, Hoehl RM, Skvarca LB, Schwarz MM, Handal LS, Crowe JE, Hartman AL. A highly potent human neutralizing antibody prevents vertical transmission of Rift Valley fever virus in a rat model. Nat Commun. 2023 07 26; 14(1):4507. PMID: 37495594; PMCID: PMC10372071.
      Citations:    Fields:    Translation:HumansAnimalsCells
    37. Albar A, Sher AC, Rosenfeld S, Ditzler M, Kraus S, Crowe J, Sangi-Haghpeykar H, Kan JH. Improved Identification of Adolescent Hip Dysplasia Using a Screening Method Based on Lateral Center Edge Angle Measurements. Acad Radiol. 2023 10; 30(10):2140-2146. PMID: 37393178.
      Citations:    Fields:    Translation:Humans
    38. Stass R, Engdahl TB, Chapman NS, Wolters RM, Handal LS, Diaz SM, Crowe JE, Bowden TA. Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody. Nat Microbiol. 2023 07; 8(7):1293-1303. PMID: 37322112; PMCID: PMC10322703.
      Citations: 2     Fields:    Translation:HumansCells
    39. Rolsma SL, Yoder SM, Nargi RS, Brady E, Jimenez-Truque N, Thomsen I, Kontos M, Carnahan RH, Sutton RE, Armstrong E, Dally L, Crowe JE, Edwards KM, Creech CB. Development of a Kinetic ELISA and Reactive B Cell Frequency Assay to Detect Respiratory Syncytial Virus Pre-Fusion F Protein-Specific Immune Responses in Infants. J Pediatric Infect Dis Soc. 2023 May 31; 12(5):298-305. PMID: 37029694; PMCID: PMC10231354.
      Citations:    Fields:    Translation:HumansCells
    40. Raju S, Adams LJ, Earnest JT, Warfield K, Vang L, Crowe JE, Fremont DH, Diamond MS. A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans. Sci Transl Med. 2023 05 17; 15(696):eade8273. PMID: 37196061; PMCID: PMC10562830.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    41. Skinner NE, Ogega CO, Frumento N, Clark KE, Paul H, Yegnasubramanian S, Schuebel K, Meyers J, Gupta A, Wheelan S, Cox AL, Crowe JE, Ray SC, Bailey JR. Corrigendum: Convergent antibody responses are associated with broad neutralization of hepatitis C virus. Front Immunol. 2023; 14:1201033. PMID: 37180140; PMCID: PMC10167485.
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    42. Parrington HM, Kose N, Armstrong E, Handal L, Diaz S, Reidy J, Dong J, Stewart-Jones GB, Shrivastava-Ranjan P, Jain S, Albari?o CG, Carnahan RH, Crowe JE. Potently neutralizing human mAbs against the zoonotic pararubulavirus Sosuga virus. JCI Insight. 2023 04 24; 8(8). PMID: 36853802; PMCID: PMC10243738.
      Citations:    Fields:    Translation:HumansCells
    43. Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Lillo AM, Sundaram S, Bloom J, Diamond MS, Crowe JE, Carnahan RH, Faissol DM. Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants. bioRxiv. 2023 Apr 24. PMID: 36324800; PMCID: PMC9628197.
      Citations:    
    44. Bukreyev A, Ilinykh P, Huang K, Gunn B, Kuzmina N, Gilchuk P, Alter G, Crowe J. Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system. Res Sq. 2023 Apr 21. PMID: 37131834; PMCID: PMC10153373.
      Citations:    
    45. Chen EC, Gilchuk P, Zost SJ, Ilinykh PA, Binshtein E, Huang K, Myers L, Bonissone S, Day S, Kona CR, Trivette A, Reidy JX, Sutton RE, Gainza C, Diaz S, Williams JK, Selverian CN, Davidson E, Saphire EO, Doranz BJ, Castellana N, Bukreyev A, Carnahan RH, Crowe JE. Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes. Cell Rep. 2023 04 25; 42(4):112370. PMID: 37029928; PMCID: PMC10556194.
      Citations:    Fields:    Translation:HumansAnimalsCells
    46. Engdahl TB, Binshtein E, Brocato RL, Kuzmina NA, Principe LM, Kwilas SA, Kim RK, Chapman NS, Porter MS, Handal LS, Diaz SM, Meiler J, Reidy JX, Trivette A, Bukreyev A, Hooper JW, Guardado-Calvo P, Rey FA, Zagol-Ikapitte IA, Tran MH, McDonald WH, Crowe JE. Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies. Elife. 2023 03 27; 12. PMID: 36971354; PMCID: PMC10115451.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    47. Skinner NE, Ogega CO, Frumento N, Clark KE, Yegnasubramanian S, Schuebel K, Meyers J, Gupta A, Wheelan S, Cox AL, Crowe JE, Ray SC, Bailey JR. Convergent antibody responses are associated with broad neutralization of hepatitis C virus. Front Immunol. 2023; 14:1135841. PMID: 37033983; PMCID: PMC10080129.
      Citations:    Fields:    Translation:HumansCells
    48. Williamson LE, Bandyopadhyay A, Bailey K, Sirohi D, Klose T, Julander JG, Kuhn RJ, Crowe JE. Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc Natl Acad Sci U S A. 2023 03 28; 120(13):e2213690120. PMID: 36961925; PMCID: PMC10068833.
      Citations:    Fields:    Translation:HumansAnimalsCells
    49. Martina CE, Crowe JE, Meiler J. Glycan masking in vaccine design: Targets, immunogens and applications. Front Immunol. 2023; 14:1126034. PMID: 37033915; PMCID: PMC10076883.
      Citations:    Fields:    Translation:Cells
    50. Rghei AD, Yates JGE, Lopes JA, Zhan X, Guilleman MM, Pei Y, van Lieshout LP, Santry LA, Bridle BW, Karimi K, Thompson B, Susta L, Crowe JE, Wootton SK. Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis. Gene Ther. 2025 Jan; 32(1):38-49. PMID: 36732618.
      Citations:    Fields:    
    51. Pilewski KA, Wall S, Richardson SI, Manamela NP, Clark K, Hermanus T, Binshtein E, Venkat R, Sautto GA, Kramer KJ, Shiakolas AR, Setliff I, Salas J, Mapengo RE, Suryadevara N, Brannon JR, Beebout CJ, Parks R, Raju N, Frumento N, Walker LM, Fechter EF, Qin JS, Murji AA, Janowska K, Thakur B, Lindenberger J, May AJ, Huang X, Sammour S, Acharya P, Carnahan RH, Ross TM, Haynes BF, Hadjifrangiskou M, Crowe JE, Bailey JR, Kalams S, Morris L, Georgiev IS. Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor. Cell Rep. 2023 02 28; 42(2):112044. PMID: 36708513; PMCID: PMC10372200.
      Citations: 1     Fields:    Translation:HumansCells
    52. Raju N, Zhan X, Das S, Karwal L, Dean HJ, Crowe JE, Carnahan RH, Georgiev IS. Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines. Cell Rep. 2022 12 13; 41(11):111807. PMID: 36516766.
      Citations:    Fields:    
    53. Fischer MFS, Meiler J, Crowe JE. Computational epitope mapping of class I fusion proteins using low complexity supervised learning methods. PLoS Comput Biol. 2022 12; 18(12):e1010230. PMID: 36477260; PMCID: PMC9762601.
      Citations: 1     Fields:    
    54. Vanover D, Zurla C, Peck HE, Orr-Burks N, Joo JY, Murray J, Holladay N, Hobbs RA, Jung Y, Chaves LCS, Rotolo L, Lifland AW, Olivier AK, Li D, Saunders KO, Sempowski GD, Crowe JE, Haynes BF, Lafontaine ER, Hogan RJ, Santangelo PJ. Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection. Adv Sci (Weinh). 2022 12; 9(34):e2202771. PMID: 36316224; PMCID: PMC9731714.
      Citations: 4     Fields:    Translation:HumansCells
    55. Ford-Siltz LA, Tohma K, Alvarado GS, Kendra JA, Pilewski KA, Crowe JE, Parra GI. Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein. Front Immunol. 2022; 13:1040836. PMID: 36389818; PMCID: PMC9641292.
      Citations: 1     Fields:    Translation:HumansCells
    56. Nkolola JP, Yu J, Wan H, Chang A, McMahan K, Anioke T, Jacob-Dolan C, Powers O, Ye T, Chandrashekar A, Sellers D, Barrett J, Loo YM, Esser MT, Carnahan RH, Crowe JE, Barouch DH. A bivalent SARS-CoV-2 monoclonal antibody combination does not affect the immunogenicity of a vector-based COVID-19 vaccine in macaques. Sci Transl Med. 2022 10 05; 14(665):eabo6160. PMID: 35857623; PMCID: PMC9348747.
      Citations:    Fields:    
    57. Mazur NI, Terstappen J, Baral R, Bardaj? A, Beutels P, Buchholz UJ, Cohen C, Crowe JE, Cutland CL, Eckert L, Feikin D, Fitzpatrick T, Fong Y, Graham BS, Heikkinen T, Higgins D, Hirve S, Klugman KP, Kragten-Tabatabaie L, Lemey P, Libster R, L?wensteyn Y, Mejias A, Munoz FM, Munywoki PK, Mwananyanda L, Nair H, Nunes MC, Ramilo O, Richmond P, Ruckwardt TJ, Sande C, Srikantiah P, Thacker N, Waldstein KA, Weinberger D, Wildenbeest J, Wiseman D, Zar HJ, Zambon M, Bont L. Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape. Lancet Infect Dis. 2023 01; 23(1):e2-e21. PMID: 35952703; PMCID: PMC9896921.
      Citations:    
    58. Frumento N, Figueroa A, Wang T, Zahid MN, Wang S, Massaccesi G, Stavrakis G, Crowe JE, Flyak AI, Ji H, Ray SC, Shaw GM, Cox AL, Bailey JR. Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency. J Clin Invest. 2022 08 01; 132(15). PMID: 35588376; PMCID: PMC9337827.
      Citations:    Fields:    
    59. Case JB, Mackin S, Errico JM, Chong Z, Madden EA, Whitener B, Guarino B, Schmid MA, Rosenthal K, Ren K, Dang HV, Snell G, Jung A, Droit L, Handley SA, Halfmann PJ, Kawaoka Y, Crowe JE, Fremont DH, Virgin HW, Loo YM, Esser MT, Purcell LA, Corti D, Diamond MS. Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains. Nat Commun. 2022 07 02; 13(1):3824. PMID: 35780162; PMCID: PMC9250508.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    60. Self WH, Wheeler AP, Stewart TG, Schrager H, Mallada J, Thomas CB, Cataldo VD, O'Neal HR, Shapiro NI, Higgins C, Ginde AA, Chauhan L, Johnson NJ, Henning DJ, Jaiswal SJ, Mammen MJ, Harris ES, Pannu SR, Laguio-Vila M, El Atrouni W, de Wit M, Hoda D, Cohn CS, McWilliams C, Shanholtz C, Jones AE, Raval JS, Mucha S, Ipe TS, Qiao X, Schrantz SJ, Shenoy A, Fremont RD, Brady EJ, Carnahan RH, Chappell JD, Crowe JE, Denison MR, Gilchuk P, Stevens LJ, Sutton RE, Thomsen I, Yoder SM, Bistran-Hall AJ, Casey JD, Lindsell CJ, Wang L, Pulley JM, Rhoads JP, Bernard GR, Rice TW, Passive Immunity Trial for Our Nation (PassITON) Investigators. Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled Trial. Chest. 2022 11; 162(5):982-994. PMID: 35780813; PMCID: PMC9247217.
      Citations:    Fields:    
    61. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine. Nat Commun. 2022 06 16; 13(1):3466. PMID: 35710908; PMCID: PMC9201272.
      Citations:    Fields:    Translation:HumansCells
    62. Bozhanova NG, Flyak AI, Brown BP, Ruiz SE, Salas J, Rho S, Bombardi RG, Myers L, Soto C, Bailey JR, Crowe JE, Bjorkman PJ, Meiler J. Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun. 2022 06 08; 13(1):3178. PMID: 35676279; PMCID: PMC9177688.
      Citations:    Fields:    Translation:HumansCells
    63. Suryadevara N, Shiakolas AR, VanBlargan LA, Binshtein E, Chen RE, Case JB, Kramer KJ, Armstrong EC, Myers L, Trivette A, Gainza C, Nargi RS, Selverian CN, Davidson E, Doranz BJ, Diaz SM, Handal LS, Carnahan RH, Diamond MS, Georgiev IS, Crowe JE. An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer. J Clin Invest. 2022 06 01; 132(11). PMID: 35472136; PMCID: PMC9151704.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    64. Vogt MR, Wright PF, Hickey WF, De Buysscher T, Boyd KL, Crowe JE. Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis. N Engl J Med. 2022 05 26; 386(21):2059-2060. PMID: 35613028; PMCID: PMC9321432.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    65. Pfaff-Kilgore JM, Davidson E, Kadash-Edmondson K, Hernandez M, Rosenberg E, Chambers R, Castelli M, Clementi N, Mancini N, Bailey JR, Crowe JE, Law M, Doranz BJ. Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening. Cell Rep. 2022 05 24; 39(8):110859. PMID: 35613596; PMCID: PMC9281441.
      Citations:    Fields:    Translation:HumansCells
    66. Fowler BD, Kose N, Reidy JX, Handal LS, Skaar EP, Crowe JE. Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter In Vivo Bacterial Burdens in a Murine Sepsis Model. Infect Immun. 2022 06 16; 90(6):e0017622. PMID: 35583347; PMCID: PMC9202393.
      Citations:    Fields:    Translation:HumansAnimalsCells
    67. Schoeder CT, Gilchuk P, Sangha AK, Ledwitch KV, Malherbe DC, Zhang X, Binshtein E, Williamson LE, Martina CE, Dong J, Armstrong E, Sutton R, Nargi R, Rodriguez J, Kuzmina N, Fiala B, King NP, Bukreyev A, Crowe JE, Meiler J. Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region. PLoS Pathog. 2022 05; 18(5):e1010518. PMID: 35584193; PMCID: PMC9170092.
      Citations:    Fields:    Translation:AnimalsCells
    68. Zhang Y, Clarke A, Regan KH, Campbell K, Donaldson S, Crowe J, Rossi AG, Hill AT. Isolated IgG2 deficiency is an independent risk factor for exacerbations in bronchiectasis. QJM. 2022 May 10; 115(5):292-297. PMID: 33970283; PMCID: PMC9086763.
      Citations:    
    69. Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, Crowe JE, Ward AB, de la Pe?a AT. Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv. 2022 05 06; 8(18):eabn2911. PMID: 35507649; PMCID: PMC9067923.
      Citations: 2     Fields:    Translation:HumansCells
    70. August A, Attarwala HZ, Himansu S, Kalidindi S, Lu S, Pajon R, Han S, Lecerf JM, Tomassini JE, Hard M, Ptaszek LM, Crowe JE, Zaks T. Author Correction: A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus. Nat Med. 2022 May; 28(5):1095-1096. PMID: 35449420; PMCID: PMC9117134.
      Citations:    Fields:    
    71. Suryadevara N, Gilchuk P, Zost SJ, Mittal N, Zhao LL, Crowe JE, Carnahan RH. Real-time cell analysis: A high-throughput approach for testing SARS-CoV-2 antibody neutralization and escape. STAR Protoc. 2022 06 17; 3(2):101387. PMID: 35578733; PMCID: PMC9023333.
      Citations:    Fields:    Translation:HumansCells
    72. Doyle MP, Genualdi JR, Bailey AL, Kose N, Gainza C, Rodriguez J, Reeder KM, Nelson CA, Jethva PN, Sutton RE, Bombardi RG, Gross ML, Julander JG, Fremont DH, Diamond MS, Crowe JE. Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus. mBio. 2022 06 28; 13(3):e0051222. PMID: 35420472; PMCID: PMC9239089.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    73. Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS. Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J Exp Med. 2022 04 04; 219(4). PMID: 35297953; PMCID: PMC9195047.
      Citations:    Fields:    Translation:AnimalsCells
    74. Hu L, Salmen W, Chen R, Zhou Y, Neill F, Crowe JE, Atmar RL, Estes MK, Prasad BVV. Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity. Nat Commun. 2022 03 10; 13(1):1241. PMID: 35273142; PMCID: PMC8913647.
      Citations: 1     Fields:    Translation:HumansCells
    75. Loo YM, McTamney PM, Arends RH, Abram ME, Aksyuk AA, Diallo S, Flores DJ, Kelly EJ, Ren K, Roque R, Rosenthal K, Streicher K, Tuffy KM, Bond NJ, Cornwell O, Bouquet J, Cheng LI, Dunyak J, Huang Y, Rosenbaum AI, Pilla Reddy V, Andersen H, Carnahan RH, Crowe JE, Kuehne AI, Herbert AS, Dye JM, Bright H, Kallewaard NL, Pangalos MN, Esser MT. The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans. Sci Transl Med. 2022 03 09; 14(635):eabl8124. PMID: 35076282; PMCID: PMC8939769.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    76. Shiakolas AR, Kramer KJ, Johnson NV, Wall SC, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker LM, Setliff I, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking. Nat Biotechnol. 2022 08; 40(8):1270-1275. PMID: 35241839; PMCID: PMC9378442.
      Citations: 3     Fields:    
    77. Crowe JE. Bispecific antiviral neutralizing antibodies are twice as nice. Nat Immunol. 2022 03; 23(3):346-347. PMID: 35228693.
      Citations:    Fields:    Translation:HumansCells
    78. Crowe JE, Carnahan RH. Even old foes can learn sweet new tricks. Cell Host Microbe. 2022 02 09; 30(2):151-153. PMID: 35143767.
      Citations:    Fields:    Translation:HumansCells
    79. Cobb RR, Nkolola J, Gilchuk P, Chandrashekar A, Yu J, House RV, Earnhart CG, Dorsey NM, Hopkins SA, Snow DM, Chen RE, VanBlargan LA, Hechenblaickner M, Hoppe B, Collins L, Tomic MT, Nonet GH, Hackett K, Slaughter JC, Lewis MG, Andersen H, Cook A, Diamond MS, Carnahan RH, Barouch DH, Crowe JE. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques. Med. 2022 Mar 11; 3(3):188-203.e4. PMID: 35132398; PMCID: PMC8810411.
      Citations: 4     Translation:HumansAnimalsCells
    80. Crowe JE. Human Antibodies for Viral Infections. Annu Rev Immunol. 2022 04 26; 40:349-386. PMID: 35113730.
      Citations: 4     Fields:    Translation:HumansAnimals
    81. VanBlargan LA, Errico JM, Halfmann PJ, Zost SJ, Crowe JE, Purcell LA, Kawaoka Y, Corti D, Fremont DH, Diamond MS. An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies. Nat Med. 2022 03; 28(3):490-495. PMID: 35046573; PMCID: PMC8767531.
      Citations: 127     Fields:    Translation:HumansCells
    82. Murin CD, Gilchuk P, Crowe JE, Ward AB. Structural Biology Illuminates Molecular Determinants of Broad Ebolavirus Neutralization by Human Antibodies for Pan-Ebolavirus Therapeutic Development. Front Immunol. 2021; 12:808047. PMID: 35082794; PMCID: PMC8784787.
      Citations:    Fields:    Translation:HumansCells
    83. Ogega CO, Skinner NE, Flyak AI, Clark KE, Board NL, Bjorkman PJ, Crowe JE, Cox AL, Ray SC, Bailey JR. B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. PLoS Pathog. 2022 01; 18(1):e1010179. PMID: 34990486; PMCID: PMC8769295.
      Citations:    Fields:    Translation:HumansCells
    84. Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK. Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236. PMID: 34967699; PMCID: PMC8726723.
      Citations: 1     Fields:    Translation:AnimalsCells
    85. Schmitz S, Schmitz EA, Crowe JE, Meiler J. The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta. MAbs. 2022 Jan-Dec; 14(1):2068212. PMID: 35544469; PMCID: PMC9103704.
      Citations:    Fields:    Translation:HumansAnimalsCells
    86. August A, Attarwala HZ, Himansu S, Kalidindi S, Lu S, Pajon R, Han S, Lecerf JM, Tomassini JE, Hard M, Ptaszek LM, Crowe JE, Zaks T. A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus. Nat Med. 2021 12; 27(12):2224-2233. PMID: 34887572; PMCID: PMC8674127.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    87. Gilchuk P, Thomsen I, Yoder S, Brady E, Chappell JD, Stevens LJ, Denison MR, Sutton RE, Chen RE, VanBlargan LA, Suryadevara N, Zost SJ, Schmitz J, Pulley JM, Diamond MS, Rhoads JP, Bernard GR, Self WH, Rice TW, Wheeler AP, Crowe JE, Carnahan RH. Standardized two-step testing of antibody activity in COVID-19 convalescent plasma. iScience. 2022 Jan 21; 25(1):103602. PMID: 34901783; PMCID: PMC8653399.
      Citations: 3     
    88. Gilchuk P, Murin CD, Cross RW, Ilinykh PA, Huang K, Kuzmina N, Borisevich V, Agans KN, Geisbert JB, Zost SJ, Nargi RS, Sutton RE, Suryadevara N, Bombardi RG, Carnahan RH, Bukreyev A, Geisbert TW, Ward AB, Crowe JE. Pan-ebolavirus protective therapy by two multifunctional human antibodies. Cell. 2021 10 28; 184(22):5593-5607.e18. PMID: 34715022; PMCID: PMC8716180.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    89. Alvarado G, Salmen W, Ettayebi K, Hu L, Sankaran B, Estes MK, Venkataram Prasad BV, Crowe JE. Author Correction: Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses. Nat Commun. 2021 Oct 14; 12(1):6090. PMID: 34650069; PMCID: PMC8516901.
      Citations:    Fields:    
    90. Wessel AW, Doyle MP, Engdahl TB, Rodriguez J, Crowe JE, Diamond MS. Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection. mBio. 2021 10 26; 12(5):e0244021. PMID: 34634945; PMCID: PMC8510529.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    91. Gilchuk IM, Bangaru S, Kose N, Bombardi RG, Trivette A, Li S, Turner HL, Carnahan RH, Ward AB, Crowe JE. Human antibody recognition of H7N9 influenza virus HA following natural infection. JCI Insight. 2021 10 08; 6(19). PMID: 34437301; PMCID: PMC8525637.
      Citations: 1     Fields:    Translation:HumansCells
    92. Dong J, Zost SJ, Greaney AJ, Starr TN, Dingens AS, Chen EC, Chen RE, Case JB, Sutton RE, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi RS, Binshtein E, Xie X, Zhang X, Shi PY, Logue J, Weston S, McGrath ME, Frieman MB, Brady T, Tuffy KM, Bright H, Loo YM, McTamney PM, Esser MT, Carnahan RH, Diamond MS, Bloom JD, Crowe JE. Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail. Nat Microbiol. 2021 10; 6(10):1233-1244. PMID: 34548634; PMCID: PMC8543371.
      Citations: 64     Fields:    Translation:HumansCells
    93. Kramer KJ, Johnson NV, Shiakolas AR, Suryadevara N, Periasamy S, Raju N, Williams JK, Wrapp D, Zost SJ, Walker LM, Wall SC, Holt CM, Hsieh CL, Sutton RE, Paulo A, Nargi RS, Davidson E, Doranz BJ, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep. 2021 10 05; 37(1):109784. PMID: 34592170; PMCID: PMC8443366.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    94. Drury SL, Miller AR, Laut CL, Walter AB, Bennett MR, Su M, Bai M, Jing B, Joseph SB, Metzger EJ, Bane CE, Black CC, Macdonald MT, Dutter BF, Romaine IM, Waterson AG, Sulikowski GA, Jansen ED, Crowe JE, Sciotti RJ, Skaar EP. Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections. Antimicrob Agents Chemother. 2021 11 17; 65(12):e0091921. PMID: 34516248; PMCID: PMC8597735.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    95. Doyle MP, Kose N, Borisevich V, Binshtein E, Amaya M, Nagel M, Annand EJ, Armstrong E, Bombardi R, Dong J, Schey KL, Broder CC, Zeitlin L, Kuang EA, Bornholdt ZA, West BR, Geisbert TW, Cross RW, Crowe JE. Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein. Cell Rep. 2021 08 31; 36(9):109628. PMID: 34469726; PMCID: PMC8527959.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    96. VanBlargan LA, Adams LJ, Liu Z, Chen RE, Gilchuk P, Raju S, Smith BK, Zhao H, Case JB, Winkler ES, Whitener BM, Droit L, Aziati ID, Bricker TL, Joshi A, Shi PY, Creanga A, Pegu A, Handley SA, Wang D, Boon ACM, Crowe JE, Whelan SPJ, Fremont DH, Diamond MS. A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope. Immunity. 2021 10 12; 54(10):2399-2416.e6. PMID: 34481543; PMCID: PMC8373659.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    97. Kim AS, Kafai NM, Winkler ES, Gilliland TC, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, Mack M, Crowe JE, Doranz BJ, Lai JR, Alter G, Gross ML, Klimstra WB, Fremont DH, Diamond MS. Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope. Cell. 2021 08 19; 184(17):4414-4429.e19. PMID: 34416146; PMCID: PMC8382027.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    98. Williamson LE, Reeder KM, Bailey K, Tran MH, Roy V, Fouch ME, Kose N, Trivette A, Nargi RS, Winkler ES, Kim AS, Gainza C, Rodriguez J, Armstrong E, Sutton RE, Reidy J, Carnahan RH, McDonald WH, Schoeder CT, Klimstra WB, Davidson E, Doranz BJ, Alter G, Meiler J, Schey KL, Julander JG, Diamond MS, Crowe JE. Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress. Cell. 2021 08 19; 184(17):4430-4446.e22. PMID: 34416147; PMCID: PMC8418820.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    99. Chen EC, Gilchuk P, Zost SJ, Suryadevara N, Winkler ES, Cabel CR, Binshtein E, Chen RE, Sutton RE, Rodriguez J, Day S, Myers L, Trivette A, Williams JK, Davidson E, Li S, Doranz BJ, Campos SK, Carnahan RH, Thorne CA, Diamond MS, Crowe JE. Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals. Cell Rep. 2021 08 24; 36(8):109604. PMID: 34411541; PMCID: PMC8352653.
      Citations: 21     Fields:    
    100. Zost SJ, Dong J, Gilchuk IM, Gilchuk P, Thornburg NJ, Bangaru S, Kose N, Finn JA, Bombardi R, Soto C, Chen EC, Nargi RS, Sutton RE, Irving RP, Suryadevara N, Westover JB, Carnahan RH, Turner HL, Li S, Ward AB, Crowe JE. Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface. J Clin Invest. 2021 08 02; 131(15). PMID: 34156974; PMCID: PMC8321569.
      Citations: 5     Fields:    Translation:HumansCells
    101. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. bioRxiv. 2021 Jul 28. PMID: 34341788; PMCID: PMC8328055.
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    102. Engdahl TB, Kuzmina NA, Ronk AJ, Mire CE, Hyde MA, Kose N, Josleyn MD, Sutton RE, Mehta A, Wolters RM, Lloyd NM, Valdivieso FR, Ksiazek TG, Hooper JW, Bukreyev A, Crowe JE. Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection. Cell Rep. 2021 Jul 20; 36(3):109453. PMID: 34289361; PMCID: PMC8357190.
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    103. Gilchuk P, Guthals A, Bonissone SR, Shaw JB, Ilinykh PA, Huang K, Bombardi RG, Liang J, Grinyo A, Davidson E, Chen EC, Gunn BM, Alter G, Saphire EO, Doranz BJ, Bukreyev A, Zeitlin L, Castellana N, Crowe JE. Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma. Front Immunol. 2021; 12:706757. PMID: 34335620; PMCID: PMC8322977.
      Citations: 1     Fields:    Translation:HumansCells
    104. Meyer M, Gunn BM, Malherbe DC, Gangavarapu K, Yoshida A, Pietzsch C, Kuzmina NA, Saphire EO, Collins PL, Crowe JE, Zhu JJ, Suchard MA, Brining DL, Mire CE, Cross RW, Geisbert JB, Samal SK, Andersen KG, Alter G, Geisbert TW, Bukreyev A. Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects. Sci Transl Med. 2021 07 14; 13(602). PMID: 34261800; PMCID: PMC8675601.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    105. Alvarado G, Salmen W, Ettayebi K, Hu L, Sankaran B, Estes MK, Venkataram Prasad BV, Crowe JE. Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses. Nat Commun. 2021 07 14; 12(1):4320. PMID: 34262046; PMCID: PMC8280134.
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    106. Kodali P, Schoeder CT, Schmitz S, Crowe JE, Meiler J. RosettaCM for antibodies with very long HCDR3s and low template availability. Proteins. 2021 11; 89(11):1458-1472. PMID: 34176159; PMCID: PMC8492515.
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    107. Shiakolas AR, Johnson N, Kramer KJ, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker L, Setliff I, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking. bioRxiv. 2021 Jun 30. PMID: 34100018; PMCID: PMC8183015.
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    108. Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Liu Z, Jo H, Lee N, Tenneti K, Eschbach JE, Shema Mugisha C, Cousins EM, Cloer EW, Vuong HR, VanBlargan LA, Bailey AL, Gilchuk P, Crowe JE, Diamond MS, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep. 2021 07 13; 36(2):109364. PMID: 34214467; PMCID: PMC8220945.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    109. Chen RE, Winkler ES, Case JB, Aziati ID, Bricker TL, Joshi A, Darling TL, Ying B, Errico JM, Shrihari S, VanBlargan LA, Xie X, Gilchuk P, Zost SJ, Droit L, Liu Z, Stumpf S, Wang D, Handley SA, Stine WB, Shi PY, Davis-Gardner ME, Suthar MS, Knight MG, Andino R, Chiu CY, Ellebedy AH, Fremont DH, Whelan SPJ, Crowe JE, Purcell L, Corti D, Boon ACM, Diamond MS. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Nature. 2021 08; 596(7870):103-108. PMID: 34153975; PMCID: PMC8349859.
      Citations: 76     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    110. Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE, Baric RS, Morris L, McLellan JS, Georgiev IS, Sch?fer A. Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions. Cell Rep Med. 2021 06 15; 2(6):100313. PMID: 34056628; PMCID: PMC8139315.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    111. Engdahl TB, Kuzmina NA, Ronk AJ, Mire CE, Hyde MA, Kose N, Josleyn MD, Sutton RE, Mehta A, Wolters RM, Lloyd NM, Ksiazek TG, Hooper JW, Bukreyev A, Crowe JE, Valdivieso FR. Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection. Cell Rep. 2021 05 04; 35(5):109086. PMID: 33951434; PMCID: PMC8142553.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    112. Chen EC, Gilchuk P, Zost SJ, Suryadevara N, Winkler ES, Cabel CR, Binshtein E, Sutton RE, Rodriguez J, Day S, Myers L, Trivette A, Williams JK, Davidson E, Li S, Doranz BJ, Campos SK, Carnahan RH, Thorne CA, Diamond MS, Crowe JE. Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals. bioRxiv. 2021 May 03. PMID: 33972937; PMCID: PMC8109196.
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    113. VanBlargan L, Adams L, Liu Z, Chen RE, Gilchuk P, Raju S, Smith B, Zhao H, Case JB, Winkler ES, Whitener B, Droit L, Aziati I, Shi PY, Creanga A, Pegu A, Handley S, Wang D, Boon A, Crowe JE, Whelan SPJ, Fremont D, Diamond M. A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope. bioRxiv. 2021 Apr 26. PMID: 33907753; PMCID: PMC8077627.
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    114. Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, Droit L, Liu Z, Stumpf S, Wang D, Handley S, Stine W, Shi PY, Garcia-Knight M, Andino R, Chiu C, Ellebedy A, Fremont D, Whelan S, Crowe J, Purcell L, Corti D, Boon A. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Res Sq. 2021 Apr 23. PMID: 34013259; PMCID: PMC8132254.
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    115. Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe JE, Ward AB. Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep. 2021 04 13; 35(2):108984. PMID: 33852862; PMCID: PMC8133395.
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    116. Chapman NS, Zhao H, Kose N, Westover JB, Kalveram B, Bombardi R, Rodriguez J, Sutton R, Genualdi J, LaBeaud AD, Mutuku FM, Pittman PR, Freiberg AN, Gowen BB, Fremont DH, Crowe JE. Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition. Proc Natl Acad Sci U S A. 2021 04 06; 118(14). PMID: 33782133; PMCID: PMC8040655.
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    117. Jones T, Day SB, Myers L, Crowe JE, Soto C. ClonoMatch: a tool for identifying homologous immunoglobulin and T-cell receptor sequences in large databases. Bioinformatics. 2021 Apr 05; 36(24):5695-5697. PMID: 33325481; PMCID: PMC8023686.
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    118. Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Chen RE, Shi PY, Carnahan RH, Thackray LB, Diamond MS, Crowe JE. Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein. Cell. 2021 04 29; 184(9):2316-2331.e15. PMID: 33773105; PMCID: PMC7962591.
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    119. Schoeder CT, Schmitz S, Adolf-Bryfogle J, Sevy AM, Finn JA, Sauer MF, Bozhanova NG, Mueller BK, Sangha AK, Sheehan JH, Kuenze G, Marlow B, Smith ST, Woods H, Bender BJ, Martina CE, Del Alamo D, Kodali P, Gulsevin A, Schief WR, Crowe JE, Meiler J, Moretti R, Bonet J, Correia BE. Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design. Biochemistry. 2021 Mar 23; 60(11):825-846. PMID: 33705117; PMCID: PMC7992133.
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    120. Chen RE, Zhang X, Case JB, Winkler ES, Liu Y, VanBlargan LA, Liu J, Errico JM, Xie X, Suryadevara N, Gilchuk P, Zost SJ, Tahan S, Droit L, Turner JS, Kim W, Schmitz AJ, Thapa M, Wang D, Boon ACM, Presti RM, O'Halloran JA, Kim AHJ, Deepak P, Pinto D, Fremont DH, Crowe JE, Corti D, Virgin HW, Ellebedy AH, Shi PY, Diamond MS. Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies. Nat Med. 2021 04; 27(4):717-726. PMID: 33664494; PMCID: PMC8058618.
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    121. Dong J, Zost S, Greaney A, Starr TN, Dingens AS, Chen EC, Chen R, Case B, Sutton R, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi R, Binshtein E, Xie X, Zhang X, Shi PY, Logue J, Weston S, McGrath M, Frieman M, Brady T, Tuffy K, Bright H, Loo YM, McvTamney P, Esser M, Carnahan R, Diamond M, Bloom J, Crowe JE. Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail. bioRxiv. 2021 Mar 01. PMID: 33532768; PMCID: PMC7852235.
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    122. Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe JE, Lok SM. Antibody affinity versus dengue morphology influences neutralization. PLoS Pathog. 2021 02; 17(2):e1009331. PMID: 33621239; PMCID: PMC7935256.
      Citations: 2     Fields:    Translation:HumansCells
    123. Winkler ES, Gilchuk P, Yu J, Bailey AL, Chen RE, Chong Z, Zost SJ, Jang H, Huang Y, Allen JD, Case JB, Sutton RE, Carnahan RH, Darling TL, Boon ACM, Mack M, Head RD, Ross TM, Crowe JE, Diamond MS. Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection. Cell. 2021 04 01; 184(7):1804-1820.e16. PMID: 33691139; PMCID: PMC7879018.
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    124. Diamond M, Chen R, Xie X, Case J, Zhang X, VanBlargan L, Liu Y, Liu J, Errico J, Winkler E, Suryadevara N, Tahan S, Turner J, Kim W, Schmitz A, Thapa M, Wang D, Boon A, Pinto D, Presti R, O'Halloran J, Kim A, Deepak P, Fremont D, Corti D, Virgin H, Crowe J, Droit L, Ellebedy A, Shi PY, Gilchuk P. SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies. Res Sq. 2021 Feb 10. PMID: 33594356; PMCID: PMC7885928.
      Citations: 5     
    125. Dagotto G, Mercado NB, Martinez DR, Hou YJ, Nkolola JP, Carnahan RH, Crowe JE, Baric RS, Barouch DH. Comparison of Subgenomic and Total RNA in SARS-CoV-2 Challenged Rhesus Macaques. J Virol. 2021 03 25; 95(8). PMID: 33472939; PMCID: PMC8103707.
      Citations: 30     Fields:    
    126. Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Carnahan RH, Thackray LB, Diamond MS, Crowe JE. Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein. bioRxiv. 2021 Jan 20. PMID: 33501445; PMCID: PMC7836115.
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    127. Winkler ES, Gilchuk P, Yu J, Bailey AL, Chen RE, Zost SJ, Jang H, Huang Y, Allen JD, Case JB, Sutton RE, Carnahan RH, Darling TL, Boon ACM, Mack M, Head RD, Ross TM, Crowe JE, Diamond MS. Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection. bioRxiv. 2020 Dec 28. PMID: 33398272; PMCID: PMC7781307.
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    128. Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE, Baric RS, Morris L, McLellan JS, Georgiev IS, Sch?fer A. Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions. bioRxiv. 2020 Dec 20. PMID: 33398266; PMCID: PMC7781301.
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    129. Dong J, Cross RW, Doyle MP, Kose N, Mousa JJ, Annand EJ, Borisevich V, Agans KN, Sutton R, Nargi R, Majedi M, Fenton KA, Reichard W, Bombardi RG, Geisbert TW, Crowe JE. Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein. Cell. 2020 12 10; 183(6):1536-1550.e17. PMID: 33306954; PMCID: PMC7771633.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    130. Williamson LE, Gilliland T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE. Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection. Cell. 2020 12 23; 183(7):1884-1900.e23. PMID: 33301709; PMCID: PMC7806206.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    131. Bozhanova NG, Sangha AK, Sevy AM, Gilchuk P, Huang K, Nargi RS, Reidy JX, Trivette A, Carnahan RH, Bukreyev A, Crowe JE, Meiler J. Discovery of Marburg virus neutralizing antibodies from virus-na?ve human antibody repertoires using large-scale structural predictions. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31142-31148. PMID: 33229516; PMCID: PMC7733803.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    132. Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE, Bloom JD. Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition. Cell Host Microbe. 2021 01 13; 29(1):44-57.e9. PMID: 33259788; PMCID: PMC7676316.
      Citations: 382     Fields:    Translation:HumansAnimalsCells
    133. Wessel AW, Kose N, Bombardi RG, Roy V, Chantima W, Mongkolsapaya J, Edeling MA, Nelson CA, Bosch I, Alter G, Screaton GR, Fremont DH, Crowe JE, Diamond MS. Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy. Nat Commun. 2020 10 19; 11(1):5278. PMID: 33077712; PMCID: PMC7572419.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    134. Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE, Hu WT, Lee FE, Sanz I. Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19. Nat Immunol. 2020 12; 21(12):1506-1516. PMID: 33028979; PMCID: PMC7739702.
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    135. Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Crowe JE, Coffey RJ. Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein. Gastroenterology. 2021 02; 160(3):958-961.e3. PMID: 33022277; PMCID: PMC7832655.
      Citations: 14     Fields:    Translation:HumansCells
    136. Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE, Bloom JD. Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition. bioRxiv. 2020 Sep 28. PMID: 32935107; PMCID: PMC7491521.
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    137. Reif DM, Chanock SJ, Edwards KM, Crowe JE. Inappropriate Citation of Vaccine Article. J Infect Dis. 2020 09 14; 222(8):1413-1414. PMID: 31158294; PMCID: PMC7749189.
      Citations:    Fields:    Translation:HumansPHPublic Health
    138. Dong J, Gilchuk I, Li S, Irving R, Goff MT, Turner HL, Ward AB, Carnahan RH, Crowe JE. Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface. J Clin Invest. 2020 09 01; 130(9):4734-4739. PMID: 32749241; PMCID: PMC7456233.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    139. Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE. Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe. 2020 11 11; 28(5):699-711.e7. PMID: 32783883; PMCID: PMC7666055.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    140. Finn JA, Dong J, Sevy AM, Parrish E, Gilchuk I, Nargi R, Scarlett-Jones M, Reichard W, Bombardi R, Voss TG, Meiler J, Crowe JE. Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring. Structure. 2020 10 06; 28(10):1124-1130.e5. PMID: 32783953; PMCID: PMC7544681.
      Citations: 6     Fields:    Translation:HumansCells
    141. Fox JM, Huang L, Tahan S, Powell LA, Crowe JE, Wang D, Diamond MS. A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice. PLoS Pathog. 2020 08; 16(8):e1008743. PMID: 32760128; PMCID: PMC7433899.
      Citations: 3     Fields:    Translation:AnimalsCells
    142. Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE, Van Hoeven N, Thackray LB, Carnahan RH. Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics. Nat Biomed Eng. 2020 11; 4(11):1030-1043. PMID: 32747832; PMCID: PMC7655621.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    143. Soto C, Finn JA, Willis JR, Day SB, Sinkovits RS, Jones T, Schmitz S, Meiler J, Branchizio A, Crowe JE. PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST. BMC Bioinformatics. 2020 Jul 16; 21(1):314. PMID: 32677886; PMCID: PMC7364545.
      Citations: 6     Fields:    Translation:HumansCells
    144. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE, Sch?fer A. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 08; 584(7821):443-449. PMID: 32668443; PMCID: PMC7584396.
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    145. Engdahl TB, Crowe JE. Humoral Immunity to Hantavirus Infection. mSphere. 2020 07 15; 5(4). PMID: 32669473; PMCID: PMC7364217.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    146. Soto C, Bombardi RG, Kozhevnikov M, Sinkovits RS, Chen EC, Branchizio A, Kose N, Day SB, Pilkinton M, Gujral M, Mallal S, Crowe JE. High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires. Cell Rep. 2020 07 14; 32(2):107882. PMID: 32668251; PMCID: PMC7433715.
      Citations: 12     Fields:    Translation:HumansCells
    147. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Nat Med. 2020 09; 26(9):1422-1427. PMID: 32651581; PMCID: PMC8194108.
      Citations: 205     Fields:    Translation:HumansCellsPHPublic Health
    148. Chen EC, Rubinstein S, Soto C, Bombardi RG, Day SB, Myers L, Zaytsev A, Majedi M, Cornell RF, Crowe JE. Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713. PMID: 32634163; PMCID: PMC7340310.
      Citations:    Fields:    Translation:HumansCells
    149. Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe JE. Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol. 2020 07 03; 5(49). PMID: 32620559; PMCID: PMC7418079.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    150. Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE. Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure. 2020 10 06; 28(10):1114-1123.e4. PMID: 32610044; PMCID: PMC7544621.
      Citations: 5     Fields:    Translation:AnimalsCells
    151. Erasmus JH, Archer J, Fuerte-Stone J, Khandhar AP, Voigt E, Granger B, Bombardi RG, Govero J, Tan Q, Durnell LA, Coler RN, Diamond MS, Crowe JE, Reed SG, Thackray LB, Carnahan RH, Van Hoeven N. Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection. Mol Ther Methods Clin Dev. 2020 Sep 11; 18:402-414. PMID: 32695842; PMCID: PMC7363633.
      Citations: 16     
    152. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE, Sch?fer A. Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals. bioRxiv. 2020 May 22. PMID: 32511409; PMCID: PMC7263556.
      Citations:    
    153. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Lee FE, Nguyen DC, Sanz I, Martinez DR, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. bioRxiv. 2020 May 13. PMID: 32511414; PMCID: PMC7263562.
      Citations:    
    154. Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, Metz S, Wong MP, Espinosa DA, Montoya M, Biering SB, Sukulpolvi-Petty S, Balmaseda A, Diamond MS, Harris E, Crowe JE, Baric RS, Kuan G. Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies. Cell Host Microbe. 2020 05 13; 27(5):710-724.e7. PMID: 32407709; PMCID: PMC7309352.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    155. Powell LA, Fox JM, Kose N, Kim AS, Majedi M, Bombardi R, Carnahan RH, Slaughter JC, Morrison TE, Diamond MS, Crowe JE. Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease. PLoS Pathog. 2020 05; 16(5):e1008517. PMID: 32365139; PMCID: PMC7252634.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    156. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Correction: Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 04; 16(4):e1008545. PMID: 32348355; PMCID: PMC7190102.
      Citations:    Fields:    
    157. Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, Saphire EO, Alter G, Crowe JE, Bukreyev A. Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host Microbe. 2020 06 10; 27(6):976-991.e11. PMID: 32320678; PMCID: PMC7292764.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    158. Hirsch J, Faber BW, Crowe JE, Verstrepen B, Cornelissen G. E. coli production process yields stable dengue 1 virus-sized particles (VSPs). Vaccine. 2020 04 09; 38(17):3305-3312. PMID: 32197924.
      Citations: 2     Fields:    Translation:AnimalsCells
    159. Sauer MF, Sevy AM, Crowe JE, Meiler J. Multi-state design of flexible proteins predicts sequences optimal for conformational change. PLoS Comput Biol. 2020 02; 16(2):e1007339. PMID: 32032348; PMCID: PMC7032724.
      Citations: 6     Fields:    Translation:Cells
    160. Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. 2020 02 18; 52(2):388-403.e12. PMID: 32023489; PMCID: PMC7111202.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    161. Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 2020 02 03; 217(2). PMID: 31757867; PMCID: PMC7041715.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    162. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE. Correction:?Tissue-Specific Expressed Antibody Variable Gene Repertoires. PLoS One. 2020; 15(1):e0228412. PMID: 31978140; PMCID: PMC6980481.
      Citations:    Fields:    
    163. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 01; 16(1):e1008103. PMID: 31945137; PMCID: PMC6964813.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    164. Ho BJ, Crowe JE, Dorfman SR, Camp EA, Yusuf S, Shenoi RP. Correlation of clinical and chest radiograph findings in pediatric submersion cases. Pediatr Radiol. 2020 04; 50(4):492-500. PMID: 31897567.
      Citations:    Fields:    Translation:Humans
    165. Schmitz S, Soto C, Crowe JE, Meiler J. Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires. MAbs. 2020 Jan-Dec; 12(1):1758291. PMID: 32397786; PMCID: PMC8648325.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    166. van de Sandt CE, Clemens EB, Grant EJ, Rowntree LC, Sant S, Halim H, Crowe J, Cheng AC, Kotsimbos TC, Richards M, Miller A, Tong SYC, Rossjohn J, Nguyen THO, Gras S, Chen W, Kedzierska K. Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph. Nat Commun. 2019 12 06; 10(1):5579. PMID: 31811120; PMCID: PMC6898063.
      Citations:    
    167. Sevy AM, Soto C, Bombardi RG, Meiler J, Crowe JE. Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures. BMC Bioinformatics. 2019 Dec 04; 20(1):629. PMID: 31801472; PMCID: PMC6894320.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    168. Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA. Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe. 2019 12 11; 26(6):729-738.e4. PMID: 31757767; PMCID: PMC6908751.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    169. Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE. Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice. Cell Host Microbe. 2019 12 11; 26(6):715-728.e8. PMID: 31757769; PMCID: PMC6941661.
      Citations: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    170. Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE, McBride JW. Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization. Infect Immun. 2019 12; 87(12). PMID: 31548319; PMCID: PMC6867850.
      Citations: 6     Fields:    Translation:HumansCells
    171. Martinez Viedma MDP, Kose N, Harris E, Crowe JE, Pickett BE, Parham L, Balmaseda A, Kuan G, Lorenzana I. Peptide arrays of three collections of human sera from patients infected with mosquito-borne viruses. F1000Res. 2019; 8:1875. PMID: 32201571; PMCID: PMC7065662.
      Citations: 4     Fields:    
    172. Cable J, Srikantiah P, Crowe JE, Pulendran B, Hill A, Ginsberg A, Koff W, Mathew A, Ng T, Jansen K, Glenn G, Permar S, Wilson I, Weiner DB, Weissman D, Rappuoli R. Vaccine innovations for emerging infectious diseases-a symposium report. Ann N Y Acad Sci. 2020 02; 1462(1):14-26. PMID: 31659752.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    173. Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE. Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. mBio. 2019 10 22; 10(5). PMID: 31641091; PMCID: PMC6805997.
      Citations: 8     Fields:    Translation:HumansCells
    174. Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT. Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. ACS Nano. 2019 10 22; 13(10):10939-10960. PMID: 31553872; PMCID: PMC6832804.
      Citations: 30     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    175. Kinchen VJ, Massaccesi G, Flyak AI, Mankowski MC, Colbert MD, Osburn WO, Ray SC, Cox AL, Crowe JE, Bailey JR. Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance. J Clin Invest. 2019 08 13; 129(11):4786-4796. PMID: 31408439; PMCID: PMC6819096.
      Citations: 11     Fields:    Translation:HumansCells
    176. Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE, Bailey JR. Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2. J Virol. 2019 07 15; 93(14). PMID: 31068427; PMCID: PMC6600205.
      Citations: 17     Fields:    Translation:HumansCells
    177. Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE. A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Sci Immunol. 2019 05 17; 4(35). PMID: 31101672; PMCID: PMC6629435.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    178. Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, Li S, Ward AB, Wilson IA, Crowe JE, Garc?a-Sastre A. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 2019 05 16; 177(5):1136-1152.e18. PMID: 31100268; PMCID: PMC6629437.
      Citations: 90     Fields:    Translation:AnimalsCells
    179. King LB, West BR, Moyer CL, Gilchuk P, Flyak A, Ilinykh PA, Bombardi R, Hui S, Huang K, Bukreyev A, Crowe JE, Saphire EO. Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun. 2019 04 17; 10(1):1788. PMID: 30996276; PMCID: PMC6470140.
      Citations: 11     Fields:    Translation:HumansCells
    180. Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE. Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms. J Infect Dis. 2019 04 08; 219(8):1264-1273. PMID: 30496483; PMCID: PMC6452300.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    181. Crowe JE. Antibody Determinants of Influenza Immunity. J Infect Dis. 2019 04 08; 219(Suppl_1):S21-S29. PMID: 30715373; PMCID: PMC6452307.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    182. Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection. J Virol. 2019 04 15; 93(8). PMID: 30728263; PMCID: PMC6450119.
      Citations: 9     Fields:    Translation:HumansCells
    183. Dong J, Finn JA, Larsen PA, Smith TPL, Crowe JE. Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol. 2019; 10:558. PMID: 30967877; PMCID: PMC6440498.
      Citations: 15     Fields:    Translation:AnimalsCells
    184. Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 2019 02; 566(7744):398-402. PMID: 30760926; PMCID: PMC6949180.
      Citations: 95     Fields:    Translation:HumansCells
    185. Engelhardt BG, Savani U, Jung DK, Powers AC, Jagasia M, Chen H, Winnick JJ, Tamboli RA, Crowe JE, Abumrad NN. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biol Blood Marrow Transplant. 2019 06; 25(6):1225-1231. PMID: 30738170; PMCID: PMC6559863.
      Citations: 6     Fields:    Translation:Humans
    186. Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Rep. 2019 02 05; 26(6):1585-1597.e4. PMID: 30726740; PMCID: PMC6420780.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    187. Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A. Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine. J Virol. 2019 02 15; 93(4). PMID: 30518655; PMCID: PMC6364037.
      Citations: 6     Fields:    Translation:AnimalsCells
    188. Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS Biol. 2019 02; 17(2):e3000139. PMID: 30716060; PMCID: PMC6375650.
      Citations: 22     Fields:    Translation:AnimalsCells
    189. Crowe JE. Influenza Virus-Specific Human Antibody Repertoire Studies. J Immunol. 2019 01 15; 202(2):368-373. PMID: 30617118; PMCID: PMC6327975.
      Citations: 6     Fields:    Translation:HumansCells
    190. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE, Rossmann MG. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1591-1596. PMID: 30642974; PMCID: PMC6358714.
      Citations: 26     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    191. Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1597-1602. PMID: 30642961; PMCID: PMC6358683.
      Citations: 13     Fields:    Translation:HumansCells
    192. Vogt MR, Crowe JE. Current Understanding of Humoral Immunity to Enterovirus D68. J Pediatric Infect Dis Soc. 2018 Dec 26; 7(suppl_2):S49-S53. PMID: 30590621.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    193. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth. PLoS One. 2018; 13(12):e0209437. PMID: 30566528; PMCID: PMC6300260.
      Citations: 5     Fields:    Translation:HumansCells
    194. Gilchuk P, Mire CE, Geisbert JB, Agans KN, Deer DJ, Cross RW, Slaughter JC, Flyak AI, Mani J, Pauly MH, Velasco J, Whaley KJ, Zeitlin L, Geisbert TW, Crowe JE. Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S565-S573. PMID: 29982718; PMCID: PMC6249568.
      Citations: 6     Fields:    Translation:Animals
    195. Ilinykh PA, Graber J, Kuzmina NA, Huang K, Ksiazek TG, Crowe JE, Bukreyev A. Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies. J Infect Dis. 2018 11 22; 218(suppl_5):S418-S422. PMID: 30060231; PMCID: PMC6249583.
      Citations: 3     Fields:    Translation:AnimalsCells
    196. Wirawan M, Fibriansah G, Marzinek JK, Lim XX, Ng TS, Sim AYL, Zhang Q, Kostyuchenko VA, Shi J, Smith SA, Verma CS, Anand G, Crowe JE, Bond PJ, Lok SM. Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure. 2019 02 05; 27(2):253-267.e8. PMID: 30471923; PMCID: PMC6365167.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    197. Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nat Microbiol. 2019 01; 4(1):187-197. PMID: 30455470; PMCID: PMC6294662.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    198. Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE, Pierson TC. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nat Microbiol. 2019 01; 4(1):71-77. PMID: 30455471; PMCID: PMC6435290.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    199. Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ. HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe. 2018 11 14; 24(5):703-716.e3. PMID: 30439340; PMCID: PMC6258177.
      Citations: 52     Fields:    Translation:HumansCells
    200. Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE, Bjorkman PJ, Shaw GM, Bailey JR. Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. Cell Host Microbe. 2018 11 14; 24(5):717-730.e5. PMID: 30439341; PMCID: PMC6250073.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    201. Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB, Kobinger GP. In?Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Rep. 2018 11 13; 25(7):1982-1993.e4. PMID: 30428362; PMCID: PMC6319964.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    202. Tsai WY, Chen HL, Tsai JJ, Dejnirattisai W, Jumnainsong A, Mongkolsapaya J, Screaton G, Crowe JE, Wang WK. Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine. J Virol. 2018 12 01; 92(23). PMID: 30185598; PMCID: PMC6232466.
      Citations: 14     Fields:    Translation:HumansCells
    203. Bramble MS, Hoff N, Gilchuk P, Mukadi P, Lu K, Doshi RH, Steffen I, Nicholson BP, Lipson A, Vashist N, Sinai C, Spencer D, Olinger G, Wemakoy EO, Pettitt J, Logue J, Marchand J, Varughese J, Bennett RS, Jahrling P, Cavet G, Serafini T, Ollmann Saphire E, Vilain E, Muyembe-Tamfum JJ, Hensely LE, Simmons G, Crowe JE, Rimoin AW, Illunga BK. Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors. J Infect Dis. 2018 11 05; 218(12):1929-1936. PMID: 30107445; PMCID: PMC6217721.
      Citations: 12     Fields:    Translation:HumansCells
    204. Alvarado G, Ettayebi K, Atmar RL, Bombardi RG, Kose N, Estes MK, Crowe JE. Human Monoclonal Antibodies That Neutralize Pandemic GII.4?Noroviruses. Gastroenterology. 2018 12; 155(6):1898-1907. PMID: 30170116; PMCID: PMC6402321.
      Citations: 32     Fields:    Translation:HumansCells
    205. Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE, Bukreyev A. Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap. PLoS Pathog. 2018 08; 14(8):e1007204. PMID: 30138408; PMCID: PMC6107261.
      Citations: 10     Fields:    Translation:HumansCells
    206. Kuzmina NA, Younan P, Gilchuk P, Santos RI, Flyak AI, Ilinykh PA, Huang K, Lubaki NM, Ramanathan P, Crowe JE, Bukreyev A. Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors. Cell Rep. 2018 08 14; 24(7):1802-1815.e5. PMID: 30110637; PMCID: PMC6697154.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    207. Meyer M, Yoshida A, Ramanathan P, Saphire EO, Collins PL, Crowe JE, Samal S, Bukreyev A. Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors. Cell Rep. 2018 08 14; 24(7):1816-1829. PMID: 30110638; PMCID: PMC6145141.
      Citations: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    208. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM, Viral Hemorrhagic Fever Immunotherapeutic Consortium, Volchkov V, Kobinger GP. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 2018 08 09; 174(4):938-952.e13. PMID: 30096313; PMCID: PMC6102396.
      Citations: 101     Fields:    Translation:AnimalsCellsPHPublic Health
    209. Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE, Lauffenburger D, Kawaoka Y, Andersen KG, Dye JM, Saphire EO, Alter G, Kobinger GP. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host Microbe. 2018 08 08; 24(2):221-233.e5. PMID: 30092199; PMCID: PMC6298217.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    210. Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE, Mukadi P, Muyembe-Tamfum JJ. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018 08 21; 49(2):363-374.e10. PMID: 30029854; PMCID: PMC6104738.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    211. Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, Ward AB, Wilson IA, Crowe JE. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 07 10; 9(1):2669. PMID: 29991715; PMCID: PMC6039445.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    212. Crowe JE. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine. Cold Spring Harb Perspect Biol. 2018 07 02; 10(7). PMID: 28663208; PMCID: PMC5829045.
      Citations: 11     Fields:    Translation:Humans
    213. Setliff I, McDonnell WJ, Raju N, Bombardi RG, Murji AA, Scheepers C, Ziki R, Mynhardt C, Shepherd BE, Mamchak AA, Garrett N, Karim SA, Mallal SA, Crowe JE, Morris L, Georgiev IS. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe. 2018 06 13; 23(6):845-854.e6. PMID: 29861170; PMCID: PMC6002606.
      Citations: 38     Fields:    Translation:HumansCells
    214. Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS. Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018 05; 557(7706):570-574. PMID: 29769725; PMCID: PMC5970976.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    215. Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, King H, Sapparapu G, Doranz BJ, Ksiazek TG, Wright DW, Saphire EO, Ward AB, Bukreyev A, Crowe JE. Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nat Microbiol. 2018 06; 3(6):670-677. PMID: 29736037; PMCID: PMC6030461.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    216. Lecouturier V, Berry C, Saulnier A, Naville S, Manin C, Girerd-Chambaz Y, Crowe JE, Jackson N, Guy B. Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclonal antibodies targeting key conformational epitopes. Vaccine. 2019 07 26; 37(32):4601-4609. PMID: 29706291.
      Citations: 2     Fields:    
    217. Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE, Diamond MS. Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus. mBio. 2018 02 27; 9(1). PMID: 29487230; PMCID: PMC5829823.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    218. Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE. Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. PLoS Pathog. 2018 02; 14(2):e1006837. PMID: 29470533; PMCID: PMC5823459.
      Citations: 16     Fields:    Translation:HumansCells
    219. Sevy AM, Panda S, Crowe JE, Meiler J, Vorobeychik Y. Integrating linear optimization with structural modeling to increase HIV neutralization breadth. PLoS Comput Biol. 2018 02; 14(2):e1005999. PMID: 29451898; PMCID: PMC5833279.
      Citations: 3     Fields:    Translation:HumansCells
    220. King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO. The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host Microbe. 2018 Jan 10; 23(1):101-109.e4. PMID: 29324225; PMCID: PMC5772738.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    221. Mankowski MC, Kinchen VJ, Wasilewski LN, Flyak AI, Ray SC, Crowe JE, Bailey JR. Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):E82-E91. PMID: 29255018; PMCID: PMC5776832.
      Citations: 31     Fields:    Translation:HumansCells
    222. Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Coloma J, Harris E, Crowe JE, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Watkins DI, Weiskopf D, Sette A, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Kuan G, Kallas EG. Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. J Virol. 2017 12 15; 91(24). PMID: 28978707; PMCID: PMC5709580.
      Citations: 96     Fields:    Translation:HumansCells
    223. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2. PMID: 29153506; PMCID: PMC5718948.
      Citations: 4     Fields:    Translation:Cells
    224. Matho MH, Schlossman A, Gilchuk IM, Miller G, Mikulski Z, Hupfer M, Wang J, Bitra A, Meng X, Xiang Y, Kaever T, Doukov T, Ley K, Crotty S, Peters B, Hsieh-Wilson LC, Crowe JE, Zajonc DM. Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8. J Biol Chem. 2018 01 05; 293(1):390-401. PMID: 29123031; PMCID: PMC5766908.
      Citations: 4     Fields:    Translation:HumansCells
    225. Lim XX, Chandramohan A, Lim XE, Crowe JE, Lok SM, Anand GS. Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3. PMID: 28823471.
      Citations: 20     Fields:    Translation:HumansCells
    226. Crowe JE. Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design. Cell Host Microbe. 2017 Aug 09; 22(2):193-206. PMID: 28799905; PMCID: PMC5700460.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    227. Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE, Diamond MS, Streblow DN. Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005637. PMID: 28628616; PMCID: PMC5491320.
      Citations: 23     Fields:    Translation:AnimalsCells
    228. Bailey JR, Flyak AI, Cohen VJ, Li H, Wasilewski LN, Snider AE, Wang S, Learn GH, Kose N, Loerinc L, Lampley R, Cox AL, Pfaff JM, Doranz BJ, Shaw GM, Ray SC, Crowe JE. Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance. JCI Insight. 2017 May 04; 2(9). PMID: 28469084; PMCID: PMC5414559.
      Citations: 61     Fields:    
    229. Crowe JE. Treating Flu with Skin of Frog. Immunity. 2017 04 18; 46(4):517-518. PMID: 28423328.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    230. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Sci Transl Med. 2017 04 05; 9(384). PMID: 28381540; PMCID: PMC5719873.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    231. Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE. Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action. J Infect Dis. 2017 04 01; 215(7):1124-1131. PMID: 28186295; PMCID: PMC5426380.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    232. Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG. A human antibody against Zika virus crosslinks the E protein to prevent infection. Nat Commun. 2017 03 16; 8:14722. PMID: 28300075; PMCID: PMC5356071.
      Citations: 60     Fields:    Translation:HumansCells
    233. Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE, de Silva AM. Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination. J Virol. 2017 03 01; 91(5). PMID: 28031369; PMCID: PMC5309932.
      Citations: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    234. Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Sci Transl Med. 2017 02 01; 9(375). PMID: 28148840; PMCID: PMC5448557.
      Citations: 25     Fields:    Translation:AnimalsCells
    235. Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Nat Microbiol. 2017 Jan 30; 2:16272. PMID: 28134915; PMCID: PMC5308794.
      Citations: 31     Fields:    Translation:Cells
    236. Mousa JJ, Kose N, Matta P, Gilchuk P, Crowe JE. A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein. Nat Microbiol. 2017 Jan 30; 2:16271. PMID: 28134924; PMCID: PMC5463187.
      Citations: 40     Fields:    Translation:HumansCells
    237. Sapparapu G, Fernandez E, Kose N, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature. 2016 12 15; 540(7633):443-447. PMID: 27819683; PMCID: PMC5583716.
      Citations: 212     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    238. Gilchuk I, Gilchuk P, Sapparapu G, Lampley R, Singh V, Kose N, Blum DL, Hughes LJ, Satheshkumar PS, Townsend MB, Kondas AV, Reed Z, Weiner Z, Olson VA, Hammarlund E, Raue HP, Slifka MK, Slaughter JC, Graham BS, Edwards KM, Eisenberg RJ, Cohen GH, Joyce S, Crowe JE. Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections. Cell. 2016 Oct 20; 167(3):684-694.e9. PMID: 27768891; PMCID: PMC5093772.
      Citations: 26     Fields:    Translation:HumansCells
    239. Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Meiler J, Crowe JE. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6849-E6858. PMID: 27791117; PMCID: PMC5098655.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    240. Culotta PA, Crowe JE, Tran QA, Jones JY, Mehollin-Ray AR, Tran HB, Donaruma-Kwoh M, Dodge CT, Camp EA, Cruz AT. Performance of computed tomography of the head to evaluate for skull fractures in infants with suspected non-accidental trauma. Pediatr Radiol. 2017 Jan; 47(1):74-81. PMID: 27744559.
      Citations: 4     Fields:    Translation:Humans
    241. Shanker S, Sapparapu G, Alvarado G, Viskovska M, Sankaran B, Atmar RL, Crowe JE, Estes MK, Prasad BV, Czak? R. Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):E5830-E5837. PMID: 27647885; PMCID: PMC5056091.
      Citations: 24     Fields:    Translation:HumansCells
    242. Crowe JE. Teaching a Clone to Walk, One Step at a Time. Cell. 2016 Sep 08; 166(6):1360-1361. PMID: 27610559.
      Citations: 2     Fields:    Translation:HumansCells
    243. Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K. A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses. Science. 2016 10 21; 354(6310):350-354. PMID: 27608667; PMCID: PMC5647781.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    244. Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR. Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression. Ann Rheum Dis. 2017 Mar; 76(3):612-619. PMID: 27597652; PMCID: PMC5446007.
      Citations:    
    245. Verma A, Basile AO, Bradford Y, Kuivaniemi H, Tromp G, Carey D, Gerhard GS, Crowe JE, Ritchie MD, Pendergrass SA. Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases. PLoS One. 2016; 11(8):e0160573. PMID: 27508393; PMCID: PMC4980020.
      Citations: 12     Fields:    Translation:Humans
    246. Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB. Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol. 2016 Aug 08; 1(9):16128. PMID: 27562261; PMCID: PMC5003320.
      Citations: 58     Fields:    Translation:HumansCells
    247. Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KMS, Torres RM, Crowe JE, Dermody TS, Diamond MS, Morrison TE. Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence. Cell Rep. 2016 08 02; 16(5):1326-1338. PMID: 27452455; PMCID: PMC5003573.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    248. Hicar MD, Chen X, Sulli C, Barnes T, Goodman J, Sojar H, Briney B, Willis J, Chukwuma VU, Kalams SA, Doranz BJ, Spearman P, Crowe JE. Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein. PLoS One. 2016; 11(7):e0158861. PMID: 27411063; PMCID: PMC4943599.
      Citations: 3     Fields:    Translation:HumansCells
    249. Cho MJ, Ellebrecht CT, Mukherjee EM, Sapparapu G, Boudreaux CE, McDonald SM, Crowe JE, Payne AS, Hammers CM. Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. J Immunol. 2016 08 15; 197(4):1065-73. PMID: 27402694; PMCID: PMC4976025.
      Citations: 11     Fields:    Translation:Humans
    250. Bangaru S, Nieusma T, Kose N, Thornburg NJ, Finn JA, Kaplan BS, King HG, Singh V, Lampley RM, Sapparapu G, Cisneros A, Edwards KM, Slaughter JC, Edupuganti S, Lai L, Richt JA, Webby RJ, Ward AB, Crowe JE. Recognition of influenza H3N2 variant virus by human neutralizing antibodies. JCI Insight. 2016 Jul 07; 1(10). PMID: 27482543; PMCID: PMC4962875.
      Citations: 12     Fields:    
    251. Sapparapu G, Alvarado G, Shanker S, Prasad BV, Atmar RL, Estes MK, Crowe JE, Czak? R. Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding. PLoS Pathog. 2016 06; 12(6):e1005719. PMID: 27355511; PMCID: PMC4927092.
      Citations: 15     Fields:    Translation:HumansCells
    252. Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE, Jardetzky TS. A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV. PLoS One. 2016; 11(5):e0155917. PMID: 27224013; PMCID: PMC4880302.
      Citations: 6     Fields:    Translation:AnimalsCells
    253. Boehme KW, Ikizler M, Iskarpatyoti JA, Wetzel JD, Willis J, Crowe JE, LaBranche CC, Montefiori DC, Wilson GJ, Dermody TS. Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1. mSphere. 2016 May-Jun; 1(3). PMID: 27303748; PMCID: PMC4888892.
      Citations: 4     Fields:    
    254. Finn JA, Koehler Leman J, Willis JR, Cisneros A, Crowe JE, Meiler J. Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints. PLoS One. 2016; 11(5):e0154811. PMID: 27182833; PMCID: PMC4868311.
      Citations: 11     Fields:    Translation:Cells
    255. Lowry D, Burke T, Galvin Z, Ryan JD, Russell J, Murphy A, Hegarty J, Stewart S, Crowe J. Is psychosocial and cognitive dysfunction misattributed to the virus in hepatitis C infection? Select psychosocial contributors identified. J Viral Hepat. 2016 08; 23(8):584-95. PMID: 27167497.
      Citations:    
    256. Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS. Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1. J Virol. 2016 May 15; 90(10):5090-5097. PMID: 26962223; PMCID: PMC4859728.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    257. Boyd SD, Crowe JE. Deep sequencing and human antibody repertoire analysis. Curr Opin Immunol. 2016 06; 40:103-9. PMID: 27065089; PMCID: PMC5203765.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    258. Clark KB, Hsiao HM, Bassit L, Crowe JE, Schinazi RF, Perng GC, Villinger F. Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells. Virology. 2016 06; 493:162-72. PMID: 27058763; PMCID: PMC5538722.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    259. Willis JR, Finn JA, Briney B, Sapparapu G, Singh V, King H, LaBranche CC, Montefiori DC, Meiler J, Crowe JE. Long antibody HCDR3s from HIV-na?ve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4446-51. PMID: 27044078; PMCID: PMC4843476.
      Citations: 15     Fields:    Translation:HumansCells
    260. Ilinykh PA, Shen X, Flyak AI, Kuzmina N, Ksiazek TG, Crowe JE, Bukreyev A. Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies. J Virol. 2016 Apr; 90(8):3890-3901. PMID: 26819310; PMCID: PMC4810552.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    261. Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, Li S, Wilson IA, Albrecht RA, Crowe JE, Garc?a-Sastre A. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J Clin Invest. 2016 Apr 01; 126(4):1482-94. PMID: 26950424; PMCID: PMC4811156.
      Citations: 36     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    262. Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO. Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. mBio. 2016 Feb 23; 7(1):e02154-15. PMID: 26908579; PMCID: PMC4791852.
      Citations: 56     Fields:    Translation:HumansCells
    263. Engelhardt BG, Paczesny S, Jung DK, Daguindau E, Jagasia M, Savani BN, Chinratanalab W, Cornell RF, Goodman S, Greer JP, Kassim AA, Sengsayadeth S, Yoder SM, Rock MT, Crowe JE. Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation. Haematologica. 2016 05; 101(5):e204-8. PMID: 26819055; PMCID: PMC5004357.
      Citations:    Fields:    Translation:HumansCells
    264. Flyak AI, Shen X, Murin CD, Turner HL, David JA, Fusco ML, Lampley R, Kose N, Ilinykh PA, Kuzmina N, Branchizio A, King H, Brown L, Bryan C, Davidson E, Doranz BJ, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Saphire EO, Ward AB, Bukreyev A, Crowe JE. Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection. Cell. 2016 Jan 28; 164(3):392-405. PMID: 26806128; PMCID: PMC4733404.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    265. Bates JT, Pickens JA, Schuster JE, Johnson M, Tollefson SJ, Williams JV, Davis NL, Johnston RE, Schultz-Darken N, Slaughter JC, Smith-House F, Crowe JE. Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates. Vaccine. 2016 Feb 10; 34(7):950-6. PMID: 26772634; PMCID: PMC4731299.
      Citations: 12     Fields:    Translation:AnimalsCells
    266. Alvarado G, Crowe JE. Development of Human Monoclonal Antibodies Against Respiratory Syncytial Virus Using a High Efficiency Human Hybridoma Technique. Methods Mol Biol. 2016; 1442:63-76. PMID: 27464688.
      Citations: 3     Fields:    Translation:HumansCells
    267. Hicar MD, Chen X, Kalams SA, Sojar H, Landucci G, Forthal DN, Spearman P, Crowe JE. Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations. Mol Immunol. 2016 Feb; 70:94-103. PMID: 26748387; PMCID: PMC4762738.
      Citations: 7     Fields:    Translation:HumansCells
    268. Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS. Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell. 2015 Nov 19; 163(5):1095-1107. PMID: 26553503; PMCID: PMC4659373.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    269. Smith SA, Nivarthi UK, de Alwis R, Kose N, Sapparapu G, Bombardi R, Kahle KM, Pfaff JM, Lieberman S, Doranz BJ, de Silva AM, Crowe JE. Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site. J Virol. 2016 01 15; 90(2):780-9. PMID: 26512092; PMCID: PMC4702676.
      Citations: 28     Fields:    Translation:HumansCells
    270. Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE, Diamond MS, Rossmann MG. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):13898-903. PMID: 26504196; PMCID: PMC4653152.
      Citations: 24     Fields:    Translation:HumansCells
    271. Gallichotte EN, Widman DG, Yount BL, Wahala WM, Durbin A, Whitehead S, Sariol CA, Crowe JE, de Silva AM, Baric RS. A new quaternary structure epitope on dengue virus serotype 2 is the target of durable type-specific neutralizing antibodies. mBio. 2015 Oct 13; 6(5):e01461-15. PMID: 26463165; PMCID: PMC4620467.
      Citations:    
    272. Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE. Erratum: Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus. Cell Host Microbe. 2015 Sep 09; 18(3):382. PMID: 39229368; PMCID: PMC11371358.
      Citations: 1     Fields:    
    273. Crowe JE, Koff WC. Deciphering the human immunome. Expert Rev Vaccines. 2015; 14(11):1421-5. PMID: 26485213.
      Citations: 5     Fields:    Translation:Humans
    274. Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE, de Silva AM, Ting JP. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1? Secretion: A Primary Human Monocyte Model. PLoS One. 2015; 10(8):e0136708. PMID: 26301593; PMCID: PMC4547738.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    275. Chukwuma VU, Hicar MD, Chen X, Nicholas KJ, Joyner A, Kalams SA, Landucci G, Forthal DN, Spearman PW, Crowe JE. Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein. PLoS One. 2015; 10(7):e0133509. PMID: 26226263; PMCID: PMC4520566.
      Citations:    Fields:    Translation:HumansCells
    276. Winarski KL, Thornburg NJ, Yu Y, Sapparapu G, Crowe JE, Spiller BW. Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):9346-51. PMID: 26170302; PMCID: PMC4522792.
      Citations: 15     Fields:    Translation:HumansCells
    277. Smith SA, Silva LA, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Khomadiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Dermody TS, Crowe JE, Fox JM, Pal P, Brien JD, Austin SK, Diamond MS. Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus. Cell Host Microbe. 2015 Jul 08; 18(1):86-95. PMID: 26159721; PMCID: PMC4501771.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    278. Sevy AM, Jacobs TM, Crowe JE, Meiler J. Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences. PLoS Comput Biol. 2015 Jul; 11(7):e1004300. PMID: 26147100; PMCID: PMC4493036.
      Citations: 19     Fields:    Translation:Cells
    279. Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JS, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM. DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science. 2015 Jul 03; 349(6243):88-91. PMID: 26138979; PMCID: PMC4672004.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    280. Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP. Spleen Tyrosine Kinase (Syk) Mediates IL-1? Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015 Jul 10; 290(28):17306-20. PMID: 26032420; PMCID: PMC4498069.
      Citations: 18     Fields:    Translation:HumansCells
    281. Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. J Clin Invest. 2015 Jun; 125(6):2523-31. PMID: 25985274; PMCID: PMC4497764.
      Citations: 17     Fields:    Translation:HumansCells
    282. DeVincenzo JP, Boeckh M, Bont L, Crowe JE, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ, Sim?es EA. Challenges and opportunities in developing respiratory syncytial virus therapeutics. J Infect Dis. 2015 Mar 15; 211 Suppl 1:S1-S20. PMID: 25713060; PMCID: PMC4345819.
      Citations: 44     Fields:    Translation:HumansCells
    283. Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE. Mechanism of human antibody-mediated neutralization of Marburg virus. Cell. 2015 Feb 26; 160(5):893-903. PMID: 25723164; PMCID: PMC4344968.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    284. Hashiguchi T, Fusco ML, Bornholdt ZA, Lee JE, Flyak AI, Matsuoka R, Kohda D, Yanagi Y, Crowe JE, Saphire EO, Hammel M. Structural basis for Marburg virus neutralization by a cross-reactive human antibody. Cell. 2015 Feb 26; 160(5):904-912. PMID: 25723165; PMCID: PMC4344967.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    285. Fibriansah G, Tan JL, Smith SA, de Alwis R, Ng TS, Kostyuchenko VA, Jadi RS, Kukkaro P, de Silva AM, Crowe JE, Lok SM. A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun. 2015 Feb 20; 6:6341. PMID: 25698059; PMCID: PMC4346626.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    286. Smith SA, Crowe JE. Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies. Microbiol Spectr. 2015 Feb; 3(1):AID-0027-2014. PMID: 26104564; PMCID: PMC8162739.
      Citations: 35     Fields:    Translation:HumansCells
    287. Hooper KA, Crowe JE, Bloom JD. Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice. J Virol. 2015 Apr; 89(7):3737-45. PMID: 25609803; PMCID: PMC4403400.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    288. Hotard AL, Lee S, Currier MG, Crowe JE, Sakamoto K, Newcomb DC, Peebles RS, Plemper RK, Moore ML. Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis. J Virol. 2015 Jan; 89(1):512-22. PMID: 25339762; PMCID: PMC4301159.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    289. de Alwis R, Williams KL, Schmid MA, Lai CY, Patel B, Smith SA, Crowe JE, Wang WK, Harris E, de Silva AM. Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera. PLoS Pathog. 2014 Oct; 10(10):e1004386. PMID: 25275316; PMCID: PMC4183589.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    290. Krause JC, Crowe JE. Committing the Oldest Sins in the Newest Kind of Ways-Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head. Microbiol Spectr. 2014 Oct; 2(5). PMID: 26104373.
      Citations: 7     Fields:    Translation:HumansCells
    291. Smith SA, de Alwis AR, Kose N, Jadi RS, de Silva AM, Crowe JE. Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones. J Virol. 2014 Nov; 88(21):12233-41. PMID: 25100837; PMCID: PMC4248927.
      Citations: 59     Fields:    Translation:HumansCells
    292. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE. Tissue-specific expressed antibody variable gene repertoires. PLoS One. 2014; 9(6):e100839. PMID: 24956460; PMCID: PMC4067404.
      Citations: 21     Fields:    Translation:HumansCells
    293. Dulek DE, Newcomb DC, Toki S, Goliniewska K, Cephus J, Reiss S, Bates JT, Crowe JE, Boyd KL, Moore ML, Zhou W, Peebles RS. STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge. J Virol. 2014 Sep 01; 88(17):9655-72. PMID: 24920804; PMCID: PMC4136353.
      Citations: 4     Fields:    Translation:AnimalsCells
    294. Almagro JC, Gilliland GL, Breden F, Scott JK, Sok D, Pauthner M, Reichert JM, Andrabi R, Mabry R, Voss JE, Abuqayyas L, Barghorn S, Ben-Jacob E, Crowe JE, Huston JS, Johnston SA, Krauland E, Lund-Johansen F, Marasco WA, Parren PW, Xu KY, Helguera G, Bl?ry M, Laur?n J. Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA. MAbs. 2014 May-Jun; 6(3):577-618. PMID: 24589717; PMCID: PMC4011904.
      Citations: 2     Fields:    Translation:HumansAnimals
    295. Bates JT, Keefer CJ, Slaughter JC, Kulp DW, Schief WR, Crowe JE. Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein. Virology. 2014 Apr; 454-455:139-44. PMID: 24725940; PMCID: PMC4004766.
      Citations: 15     Fields:    Translation:HumansCells
    296. Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE, Johnson PR, Schief WR, Correia BE. Proof of principle for epitope-focused vaccine design. Nature. 2014 Mar 13; 507(7491):201-6. PMID: 24499818; PMCID: PMC4260937.
      Citations: 230     Fields:    Translation:AnimalsCells
    297. Bisset GS, Crowe J. Diagnostic errors in interpretation of pediatric musculoskeletal radiographs at common injury sites. Pediatr Radiol. 2014 May; 44(5):552-7. PMID: 24445883.
      Citations: 5     Fields:    Translation:Humans
    298. Fibriansah G, Tan JL, Smith SA, de Alwis AR, Ng TS, Kostyuchenko VA, Ibarra KD, Wang J, Harris E, de Silva A, Crowe JE, Lok SM. A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface. EMBO Mol Med. 2014 03; 6(3):358-71. PMID: 24421336; PMCID: PMC3958310.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    299. Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS. Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1939-44. PMID: 24385585; PMCID: PMC3918811.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    300. Alonas E, Lifland AW, Gudheti M, Vanover D, Jung J, Zurla C, Kirschman J, Fiore VF, Douglas A, Barker TH, Yi H, Wright ER, Crowe JE, Santangelo PJ. Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. ACS Nano. 2014 Jan 28; 8(1):302-15. PMID: 24351207; PMCID: PMC3906890.
      Citations: 14     Fields:    Translation:HumansCells
    301. Smith SA, de Alwis AR, Kose N, Harris E, Ibarra KD, Kahle KM, Pfaff JM, Xiang X, Doranz BJ, de Silva AM, Austin SK, Sukupolvi-Petty S, Diamond MS, Crowe JE. The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein. mBio. 2013 Nov 19; 4(6):e00873-13. PMID: 24255124; PMCID: PMC3870244.
      Citations: 83     Fields:    Translation:HumansCells
    302. Sapparapu G, Sims AL, Aiyegbo MS, Shaikh FY, Harth EM, Crowe JE. Intracellular neutralization of a virus using a cell-penetrating molecular transporter. Nanomedicine (Lond). 2014 Aug; 9(11):1613-24. PMID: 24195674.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    303. Aiyegbo MS, Eli IM, Spiller BW, Williams DR, Kim R, Lee DE, Liu T, Li S, Stewart PL, Crowe JE. Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody. J Virol. 2014 Jan; 88(1):469-76. PMID: 24155406; PMCID: PMC3911710.
      Citations: 10     Fields:    Translation:Cells
    304. Finn JA, Crowe JE. Impact of new sequencing technologies on studies of the human B cell repertoire. Curr Opin Immunol. 2013 Oct; 25(5):613-8. PMID: 24161653; PMCID: PMC3882336.
      Citations: 17     Fields:    Translation:HumansCells
    305. Munden MM, Williams JL, Zhang W, Crowe JE, Munden RF, Cisek LJ. Intermittent testicular torsion in the pediatric patient: sonographic indicators of a difficult diagnosis. AJR Am J Roentgenol. 2013 Oct; 201(4):912-8. PMID: 24059384.
      Citations: 6     Fields:    Translation:Humans
    306. Hong M, Lee PS, Hoffman RM, Zhu X, Krause JC, Laursen NS, Yoon SI, Song L, Tussey L, Crowe JE, Ward AB, Wilson IA. Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. J Virol. 2013 Nov; 87(22):12471-80. PMID: 24027321; PMCID: PMC3807900.
      Citations: 85     Fields:    Translation:HumansCellsPHPublic Health
    307. Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE. Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J Clin Invest. 2013 Oct; 123(10):4405-9. PMID: 23999429; PMCID: PMC3784541.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    308. Crowe JE. Universal flu vaccines: primum non nocere. Sci Transl Med. 2013 Aug 28; 5(200):200fs34. PMID: 23986396.
      Citations: 12     Fields:    Translation:HumansCells
    309. Stone JW, Thornburg NJ, Blum DL, Kuhn SJ, Wright DW, Crowe JE. Gold nanorod vaccine for respiratory syncytial virus. Nanotechnology. 2013 Jul 26; 24(29):295102. PMID: 23799651; PMCID: PMC3754908.
      Citations: 25     Fields:    Translation:HumansCells
    310. Crowe JE. Immunology. Crowdsourcing immunity. Science. 2013 May 10; 340(6133):692-3. PMID: 23661747.
      Citations:    Fields:    Translation:HumansAnimalsCells
    311. Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL, Nannemann DP, Meiler J, Stewart PL, Crowe JE. Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. PLoS One. 2013; 8(5):e61101. PMID: 23671563; PMCID: PMC3650007.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    312. Willis JR, Briney BS, DeLuca SL, Crowe JE, Meiler J. Human germline antibody gene segments encode polyspecific antibodies. PLoS Comput Biol. 2013 Apr; 9(4):e1003045. PMID: 23637590; PMCID: PMC3636087.
      Citations: 36     Fields:    Translation:HumansCells
    313. Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Sette A, Schumacher TN, Link AJ, Joyce S, Buus S. Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest. 2013 May; 123(5):1976-87. PMID: 23543059; PMCID: PMC3635741.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    314. Smith SA, de Alwis R, Kose N, Durbin AP, Whitehead SS, de Silva AM, Crowe JE. Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics. J Infect Dis. 2013 Jun 15; 207(12):1898-908. PMID: 23526830; PMCID: PMC3654755.
      Citations: 46     Fields:    Translation:HumansCellsPHPublic Health
    315. Briney BS, Crowe JE. Secondary mechanisms of diversification in the human antibody repertoire. Front Immunol. 2013; 4:42. PMID: 23483107; PMCID: PMC3593266.
      Citations: 14     Fields:    
    316. Bates JT, Keefer CJ, Utley TJ, Correia BE, Schief WR, Crowe JE. Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency. J Immunol. 2013 Apr 01; 190(7):3732-9. PMID: 23455501; PMCID: PMC3608519.
      Citations: 11     Fields:    Translation:HumansCells
    317. Xu R, Krause JC, McBride R, Paulson JC, Crowe JE, Wilson IA. A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol. 2013 Mar; 20(3):363-70. PMID: 23396351; PMCID: PMC3594569.
      Citations: 84     Fields:    Translation:HumansCells
    318. Zeitlin L, Bohorov O, Bohorova N, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Barnard DL, Bates JT, Crowe JE, Piedra PA, Gilbert BE. Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs. 2013 Mar-Apr; 5(2):263-9. PMID: 23396091; PMCID: PMC3893236.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    319. Shaikh FY, Crowe JE. Molecular mechanisms driving respiratory syncytial virus assembly. Future Microbiol. 2013 Jan; 8(1):123-31. PMID: 23252497; PMCID: PMC3577052.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    320. Thornburg NJ, Hayward SL, Crowe JE. Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-?B. mBio. 2012 Dec 18; 3(6). PMID: 23249809; PMCID: PMC3529541.
      Citations: 47     Fields:    Translation:HumansCells
    321. Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. PLoS Pathog. 2012; 8(12):e1003067. PMID: 23236279; PMCID: PMC3516549.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    322. Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, Crotty S. Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. J Virol. 2013 Feb; 87(3):1569-85. PMID: 23152530; PMCID: PMC3554146.
      Citations: 14     Fields:    Translation:HumansCells
    323. Hotard AL, Shaikh FY, Lee S, Yan D, Teng MN, Plemper RK, Crowe JE, Moore ML. A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis. Virology. 2012 Dec 05; 434(1):129-36. PMID: 23062737; PMCID: PMC3492879.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    324. Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE, Barbas CF. A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase. Chembiochem. 2012 Oct 15; 13(15):2191-5. PMID: 22965667; PMCID: PMC3517015.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    325. Briney BS, Willis JR, Hicar MD, Thomas JW, Crowe JE. Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire. Immunology. 2012 Sep; 137(1):56-64. PMID: 22612413; PMCID: PMC3449247.
      Citations: 34     Fields:    Translation:HumansCells
    326. Engelhardt BG, Sengsayadeth SM, Jagasia M, Savani BN, Kassim AA, Lu P, Shyr Y, Yoder SM, Rock MT, Crowe JE. Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival. Exp Hematol. 2012 Dec; 40(12):974-982.e1. PMID: 22885125; PMCID: PMC3611587.
      Citations: 8     Fields:    Translation:HumansCells
    327. Crowe JE. Influenza virus resistance to human neutralizing antibodies. mBio. 2012; 3(4):e00213-12. PMID: 22851660; PMCID: PMC3419524.
      Citations: 1     Fields:    Translation:HumansCells
    328. Shaikh FY, Utley TJ, Craven RE, Rogers MC, Lapierre LA, Goldenring JR, Crowe JE. Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins. PLoS One. 2012; 7(7):e40826. PMID: 22808269; PMCID: PMC3396619.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    329. Briney BS, Willis JR, Crowe JE. Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity. Genes Immun. 2012 Oct; 13(7):523-9. PMID: 22717702; PMCID: PMC3449029.
      Citations:    
    330. Briney BS, Willis JR, McKinney BA, Crowe JE. High-throughput antibody sequencing reveals genetic evidence of global regulation of the na?ve and memory repertoires that extends across individuals. Genes Immun. 2012 Sep; 13(6):469-73. PMID: 22622198.
      Citations:    
    331. Lifland AW, Jung J, Alonas E, Zurla C, Crowe JE, Santangelo PJ. Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS. J Virol. 2012 Aug; 86(15):8245-58. PMID: 22623778; PMCID: PMC3421640.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    332. Briney BS, Willis JR, Crowe JE. Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes. PLoS One. 2012; 7(5):e36750. PMID: 22590602; PMCID: PMC3348910.
      Citations: 78     Fields:    Translation:HumansCellsCTClinical Trials
    333. de Alwis R, Smith SA, Olivarez NP, Messer WB, Huynh JP, Wahala WM, White LJ, Diamond MS, Baric RS, Crowe JE, de Silva AM. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7439-44. PMID: 22499787; PMCID: PMC3358852.
      Citations: 217     Fields:    Translation:HumansAnimalsCells
    334. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, Basler CF, Crowe JE, Garc?a-Sastre A. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol. 2012 Jun; 86(11):6334-40. PMID: 22457520; PMCID: PMC3372199.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    335. Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE, Jardetzky TS. Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol. 2012 Mar 04; 19(4):461-3. PMID: 22388735; PMCID: PMC3546531.
      Citations: 42     Fields:    Translation:HumansCells
    336. Shaikh FY, Cox RG, Lifland AW, Hotard AL, Williams JV, Moore ML, Santangelo PJ, Crowe JE. A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles. mBio. 2012; 3(1). PMID: 22318318; PMCID: PMC3280462.
      Citations: 34     Fields:    Translation:HumansCells
    337. Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Moore DJ, Yoder SM, Rock MT, Jagasia M, Weitkamp JH. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood. 2012 Mar 08; 119(10):2417-21. PMID: 22262764; PMCID: PMC3311262.
      Citations: 9     Fields:    Translation:HumansCells
    338. Dochow M, Krumm SA, Crowe JE, Moore ML, Plemper RK. Independent structural domains in paramyxovirus polymerase protein. J Biol Chem. 2012 Feb 24; 287(9):6878-91. PMID: 22215662; PMCID: PMC3307299.
      Citations: 34     Fields:    Translation:AnimalsCells
    339. Smith SA, Zhou Y, Olivarez NP, Broadwater AH, de Silva AM, Crowe JE. Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection. J Virol. 2012 Mar; 86(5):2665-75. PMID: 22171265; PMCID: PMC3302281.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    340. Zhang GL, Ansari HR, Bradley P, Cawley GC, Hertz T, Hu X, Jojic N, Kim Y, Kohlbacher O, Lund O, Lundegaard C, Magaret CA, Nielsen M, Papadopoulos H, Raghava GP, Tal VS, Xue LC, Yanover C, Zhu S, Rock MT, Crowe JE, Panayiotou C, Polycarpou MM, Duch W, Brusic V. Machine learning competition in immunology - Prediction of HLA class I binding peptides. J Immunol Methods. 2011 Nov 30; 374(1-2):1-4. PMID: 21986107.
      Citations: 32     Fields:    Translation:HumansCells
    341. Joyner AS, Willis JR, Crowe JE, Aiken C. Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog. 2011 Sep; 7(9):e1002234. PMID: 21931551; PMCID: PMC3169560.
      Citations: 30     Fields:    Translation:HumansCells
    342. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE. Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J Immunol. 2011 Oct 01; 187(7):3704-11. PMID: 21880983; PMCID: PMC3178754.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    343. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. J Virol. 2011 Oct; 85(20):10905-8. PMID: 21849447; PMCID: PMC3187471.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    344. Rock MT, McKinney BA, Yoder SM, Prudom CE, Wright DW, Crowe JE. Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. J Immunol Methods. 2011 Nov 30; 374(1-2):13-7. PMID: 21854782; PMCID: PMC3220792.
      Citations: 10     Fields:    Translation:HumansCells
    345. Lindquist ME, Mainou BA, Dermody TS, Crowe JE. Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Virology. 2011 Apr 25; 413(1):103-10. PMID: 21377708; PMCID: PMC3072468.
      Citations: 42     Fields:    Translation:HumansCells
    346. Schlesinger AE, Crowe JE. Sagittal orientation of ingested coins in the esophagus in children. AJR Am J Roentgenol. 2011 Mar; 196(3):670-2. PMID: 21343512.
      Citations: 5     Fields:    Translation:Humans
    347. Krause JC, Ekiert DC, Tumpey TM, Smith PB, Wilson IA, Crowe JE. An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. mBio. 2011; 2(1):e00345-10. PMID: 21304166; PMCID: PMC3037006.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    348. Pishchany G, McCoy AL, Torres VJ, Krause JC, Crowe JE, Fabry ME, Skaar EP. Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host Microbe. 2010 Dec 16; 8(6):544-50. PMID: 21147468; PMCID: PMC3032424.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    349. Monsalvo AC, Batalle JP, Lopez MF, Krause JC, Klemenc J, Hernandez JZ, Maskin B, Bugna J, Rubinstein C, Aguilar L, Dalurzo L, Libster R, Savy V, Baumeister E, Aguilar L, Cabral G, Font J, Solari L, Weller KP, Johnson J, Echavarria M, Edwards KM, Chappell JD, Crowe JE, Williams JV, Melendi GA, Polack FP. Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med. 2011 Feb; 17(2):195-9. PMID: 21131958; PMCID: PMC3034774.
      Citations: 131     Fields:    Translation:HumansCells
    350. Thornburg NJ, Shepherd B, Crowe JE. Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection. J Virol. 2010 Dec; 84(24):12895-902. PMID: 20926560; PMCID: PMC3004333.
      Citations: 27     Fields:    Translation:HumansCells
    351. Lindquist ME, Lifland AW, Utley TJ, Santangelo PJ, Crowe JE. Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. J Virol. 2010 Dec; 84(23):12274-84. PMID: 20844027; PMCID: PMC2976418.
      Citations: 93     Fields:    Translation:HumansCells
    352. Davis NA, Crowe JE, Pajewski NM, McKinney BA. Surfing a genetic association interaction network to identify modulators of antibody response to smallpox vaccine. Genes Immun. 2010 Dec; 11(8):630-6. PMID: 20613780; PMCID: PMC3001955.
      Citations:    
    353. Hicar MD, Chen X, Briney B, Hammonds J, Wang JJ, Kalams S, Spearman PW, Crowe JE. Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV. J Acquir Immune Defic Syndr. 2010 Jul; 54(3):223-35. PMID: 20531016; PMCID: PMC2930513.
      Citations: 26     Fields:    Translation:HumansCells
    354. Williams JV, Edwards KM, Weinberg GA, Griffin MR, Hall CB, Zhu Y, Szilagyi PG, Wang CK, Yang CF, Silva D, Ye D, Spaete RR, Crowe JE. Population-based incidence of human metapneumovirus infection among hospitalized children. J Infect Dis. 2010 Jun 15; 201(12):1890-8. PMID: 20446850; PMCID: PMC2873123.
      Citations: 51     Fields:    Translation:HumansCells
    355. Engelhardt BG, Jagasia M, Savani BN, Bratcher NL, Greer JP, Jiang A, Kassim AA, Lu P, Schuening F, Yoder SM, Rock MT, Crowe JE. Regulatory T cell expression of CLA or a(4)?(7) and skin or gut acute GVHD outcomes. Bone Marrow Transplant. 2011 Mar; 46(3):436-42. PMID: 20577222; PMCID: PMC3217583.
      Citations:    
    356. Hicar MD, Kalams SA, Spearman PW, Crowe JE. Emerging studies of human HIV-specific antibody repertoires. Vaccine. 2010 May 26; 28 Suppl 2:B18-23. PMID: 20510738; PMCID: PMC2879399.
      Citations: 7     Fields:    Translation:HumansCells
    357. Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE, Wilson IA. Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science. 2010 Apr 16; 328(5976):357-60. PMID: 20339031; PMCID: PMC2897825.
      Citations: 330     Fields:    Translation:HumansCellsPHPublic Health
    358. Engelhardt BG, Crowe JE. Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells. Curr Top Microbiol Immunol. 2010; 341:121-46. PMID: 20563712; PMCID: PMC3793903.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    359. Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE. Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. J Virol. 2010 Mar; 84(6):3127-30. PMID: 20042511; PMCID: PMC2826039.
      Citations: 56     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    360. Crowe JE. Recent advances in the study of human antibody responses to influenza virus using optimized human hybridoma approaches. Vaccine. 2009 Dec 30; 27 Suppl 6:G47-51. PMID: 20006140; PMCID: PMC2835990.
      Citations: 9     Fields:    Translation:HumansCells
    361. Williams JV, Blum DL, LaFleur BJ, Crowe JE, Weitkamp JH. The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol Immunol. 2009 Dec; 47(2-3):407-14. PMID: 19804909; PMCID: PMC2788105.
      Citations: 21     Fields:    Translation:HumansCells
    362. Yang CF, Wang CK, Tollefson SJ, Piyaratna R, Lintao LD, Chu M, Liem A, Mark M, Spaete RR, Crowe JE, Williams JV. Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. Virol J. 2009 Sep 09; 6:138. PMID: 19740442; PMCID: PMC2753315.
      Citations: 39     Fields:    Translation:HumansCells
    363. Talbot HK, Shepherd BE, Crowe JE, Griffin MR, Edwards KM, Podsiad AB, Tollefson SJ, Wright PF, Williams JV. The pediatric burden of human coronaviruses evaluated for twenty years. Pediatr Infect Dis J. 2009 Aug; 28(8):682-7. PMID: 19633513; PMCID: PMC2765860.
      Citations: 42     Fields:    Translation:HumansCells
    364. Talbot HK, Crowe JE, Edwards KM, Griffin MR, Zhu Y, Weinberg GA, Szilagyi PG, Hall CB, Podsiad AB, Iwane M, Williams JV, New Vaccine Surveillance Network. Coronavirus infection and hospitalizations for acute respiratory illness in young children. J Med Virol. 2009 May; 81(5):853-6. PMID: 19319948; PMCID: PMC2767383.
      Citations: 37     Fields:    Translation:HumansCellsPHPublic Health
    365. Santangelo PJ, Lifland AW, Curt P, Sasaki Y, Bassell GJ, Lindquist ME, Crowe JE. Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods. 2009 May; 6(5):347-9. PMID: 19349979; PMCID: PMC4297622.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    366. McKinney BA, Crowe JE, Guo J, Tian D. Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet. 2009 Mar; 5(3):e1000432. PMID: 19300503; PMCID: PMC2653647.
      Citations: 53     Fields:    Translation:Humans
    367. Moore ML, Chi MH, Luongo C, Lukacs NW, Polosukhin VV, Huckabee MM, Newcomb DC, Buchholz UJ, Crowe JE, Goleniewska K, Williams JV, Collins PL, Peebles RS. A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction. J Virol. 2009 May; 83(9):4185-94. PMID: 19211758; PMCID: PMC2668460.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    368. Nam KT, Lee HJ, Mok H, Romero-Gallo J, Crowe JE, Peek RM, Goldenring JR. Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology. 2009 Apr; 136(4):1288-96. PMID: 19230855; PMCID: PMC2844775.
      Citations: 37     Fields:    Translation:Animals
    369. Derdowski A, Peters TR, Glover N, Qian R, Utley TJ, Burnett A, Williams JV, Spearman P, Crowe JE. Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation. J Gen Virol. 2008 Nov; 89(Pt 11):2698-2708. PMID: 18931065; PMCID: PMC2876975.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    370. Reif DM, Motsinger-Reif AA, McKinney BA, Rock MT, Crowe JE, Moore JH. Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination. Genes Immun. 2009 Mar; 10(2):112-9. PMID: 18923431; PMCID: PMC2692715.
      Citations:    
    371. Mok H, Tollefson SJ, Podsiad AB, Shepherd BE, Polosukhin VV, Johnston RE, Williams JV, Crowe JE. An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. J Virol. 2008 Nov; 82(22):11410-8. PMID: 18786987; PMCID: PMC2573258.
      Citations: 26     Fields:    Translation:AnimalsCells
    372. Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, Crowe JE. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 2008 Sep 25; 455(7212):532-6. PMID: 18716625; PMCID: PMC2848880.
      Citations: 185     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    373. Mok H, Lee S, Wright DW, Crowe JE. Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope. Vaccine. 2008 Sep 02; 26(37):4775-82. PMID: 18662734; PMCID: PMC2561208.
      Citations: 9     Fields:    Translation:AnimalsCells
    374. Utley TJ, Ducharme NA, Varthakavi V, Shepherd BE, Santangelo PJ, Lindquist ME, Goldenring JR, Crowe JE. Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10209-14. PMID: 18621683; PMCID: PMC2481327.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    375. Reif DM, McKinney BA, Motsinger AA, Chanock SJ, Edwards KM, Rock MT, Moore JH, Crowe JE. Genetic basis for adverse events after smallpox vaccination. J Infect Dis. 2008 Jul 01; 198(1):16-22. PMID: 18454680; PMCID: PMC2746083.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    376. Yu X, McGraw PA, House FS, Crowe JE. An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods. 2008 Jul 31; 336(2):142-51. PMID: 18514220; PMCID: PMC2519117.
      Citations: 70     Fields:    Translation:HumansCells
    377. Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE. Functional maturation of the human antibody response to rotavirus. J Immunol. 2008 Mar 15; 180(6):3980-9. PMID: 18322207.
      Citations: 19     Fields:    Translation:HumansCells
    378. Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE. Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones. J Immunol. 2008 Mar 01; 180(5):3279-88. PMID: 18292552.
      Citations: 30     Fields:    Translation:HumansCells
    379. Mok H, Lee S, Utley TJ, Shepherd BE, Polosukhin VV, Collier ML, Davis NL, Johnston RE, Crowe JE. Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. J Virol. 2007 Dec; 81(24):13710-22. PMID: 17928349; PMCID: PMC2168850.
      Citations: 43     Fields:    Translation:AnimalsCellsPHPublic Health
    380. McKinney BA, Kallewaard NL, Crowe JE, Meiler J. Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site. Immunome Res. 2007 Sep 18; 3:8. PMID: 17877819; PMCID: PMC2042970.
      Citations: 9     
    381. McKinney BA, Reif DM, White BC, Crowe JE, Moore JH. Evaporative cooling feature selection for genotypic data involving interactions. Bioinformatics. 2007 Aug 15; 23(16):2113-20. PMID: 17586549; PMCID: PMC3988427.
      Citations:    
    382. Crowe JE. Genetic predisposition for adverse events after vaccination. J Infect Dis. 2007 Jul 15; 196(2):176-7. PMID: 17570102.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    383. Williams JV, Chen Z, Cseke G, Wright DW, Keefer CJ, Tollefson SJ, Hessell A, Podsiad A, Shepherd BE, Sanna PP, Burton DR, Crowe JE, Williamson RA. A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J Virol. 2007 Aug; 81(15):8315-24. PMID: 17522220; PMCID: PMC1951312.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    384. Greenbaum JA, Andersen PH, Blythe M, Bui HH, Cachau RE, Crowe J, Davies M, Kolaskar AS, Lund O, Morrison S, Mumey B, Ofran Y, Pellequer JL, Pinilla C, Ponomarenko JV, Raghava GP, van Regenmortel MH, Roggen EL, Sette A, Schlessinger A, Sollner J, Zand M, Peters B. Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools. J Mol Recognit. 2007 Mar-Apr; 20(2):75-82. PMID: 17205610.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    385. Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE. Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human na?ve and memory B cells. Mol Immunol. 2007 Mar; 44(9):2173-83. PMID: 17196657; PMCID: PMC1859862.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    386. Lee S, Miller SA, Wright DW, Rock MT, Crowe JE. Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. J Virol. 2007 Mar; 81(5):2349-58. PMID: 17182672; PMCID: PMC1865932.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    387. Cseke G, Wright DW, Tollefson SJ, Johnson JE, Crowe JE, Williams JV. Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol. 2007 Jan; 81(2):698-707. PMID: 17050599; PMCID: PMC1797435.
      Citations: 37     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    388. Miller SA, Tollefson S, Crowe JE, Williams JV, Wright DW. Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region. J Virol. 2007 Jan; 81(1):141-9. PMID: 17035305; PMCID: PMC1797239.
      Citations: 17     Fields:    Translation:Cells
    389. McKinney BA, Reif DM, Rock MT, Edwards KM, Kingsmore SF, Moore JH, Crowe JE. Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis. 2006 Aug 15; 194(4):444-53. PMID: 16845627; PMCID: PMC1620015.
      Citations: 25     Fields:    Translation:HumansCells
    390. Rock MT, Yoder SM, Talbot TR, Edwards KM, Crowe JE. Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine. J Infect Dis. 2006 Aug 15; 194(4):435-43. PMID: 16845626.
      Citations: 11     Fields:    Translation:HumansCells
    391. Tian C, Kron GK, Dischert KM, Higginbotham JN, Crowe JE. Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells. Immunology. 2006 Sep; 119(1):54-62. PMID: 16764687; PMCID: PMC1782340.
      Citations: 10     Fields:    Translation:HumansCells
    392. Venkataraman S, Allison DP, Qi H, Morrell-Falvey JL, Kallewaard NL, Crowe JE, Doktycz MJ. Automated image analysis of atomic force microscopy images of rotavirus particles. Ultramicroscopy. 2006 Jun-Jul; 106(8-9):829-37. PMID: 16730407.
      Citations:    
    393. Lafleur BJ, Crowe JE, Weitkamp JH. Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells. Hum Immunol. 2006 Jan-Feb; 67(1-2):33-42. PMID: 16698423.
      Citations: 9     Fields:    Translation:HumansCells
    394. Bowen AL, Tian C, LaFleur BJ, Crowe JE. Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth. Hum Immunol. 2006 Jan-Feb; 67(1-2):43-6. PMID: 16698424.
      Citations: 4     Fields:    Translation:HumansCells
    395. McKinney BA, Crowe JE, Voss HU, Crooke PS, Barney N, Moore JH. Hybrid grammar-based approach to nonlinear dynamical system identification from biological time series. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Feb; 73(2 Pt 1):021912. PMID: 16605367.
      Citations:    
    396. Williams JV, Wang CK, Yang CF, Tollefson SJ, House FS, Heck JM, Chu M, Brown JB, Lintao LD, Quinto JD, Chu D, Spaete RR, Edwards KM, Wright PF, Crowe JE. The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J Infect Dis. 2006 Feb 01; 193(3):387-95. PMID: 16388486; PMCID: PMC1586246.
      Citations: 108     Fields:    Translation:HumansCellsPHPublic Health
    397. Martino R, Rabella N, Williams JV, Margall N, Labeaga R, Crowe JE, Coll P, Sierra J, Porras RP, R?mila E. Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies. Biol Blood Marrow Transplant. 2005 Oct; 11(10):781-96. PMID: 16182179; PMCID: PMC3347977.
      Citations: 88     Fields:    Translation:HumansCellsPHPublic Health
    398. Brock SC, Heck JM, McGraw PA, Crowe JE. The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence. J Virol. 2005 Oct; 79(19):12528-35. PMID: 16160180; PMCID: PMC1211512.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    399. Williams JV, Tollefson SJ, Johnson JE, Crowe JE. The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol. 2005 Sep; 79(17):10944-51. PMID: 16103146; PMCID: PMC1193579.
      Citations: 59     Fields:    Translation:AnimalsCells
    400. Williams JV, Crowe JE, Enriquez R, Minton P, Peebles RS, Hamilton RG, Higgins S, Griffin M, Hartert TV. Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis. 2005 Oct 01; 192(7):1149-53. PMID: 16136455; PMCID: PMC1476781.
      Citations: 67     Fields:    Translation:HumansCells
    401. Williams JV, Martino R, Otegui M, Parody R, Heck JM, Crowe JE, Rabella N. A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis. 2005 Sep 15; 192(6):1061-5. PMID: 16107960; PMCID: PMC1483060.
      Citations: 80     Fields:    Translation:HumansCells
    402. Rutigliano JA, Rock MT, Johnson AK, Crowe JE, Graham BS. Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Virology. 2005 Jul 05; 337(2):335-43. PMID: 15916793.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    403. Williams JV, Tollefson SJ, Heymann PW, Carper HT, Patrie J, Crowe JE. Human metapneumovirus infection in children hospitalized for wheezing. J Allergy Clin Immunol. 2005 Jun; 115(6):1311-2. PMID: 15940152; PMCID: PMC1476700.
      Citations: 38     Fields:    Translation:HumansCells
    404. Lafleur BJ, Greenberg HB, Crowe JE, Weitkamp JH. Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes. Hum Immunol. 2005 Jun; 66(6):666-76. PMID: 15993712.
      Citations: 17     Fields:    Translation:HumansCells
    405. Chen X, Rock MT, Hammonds J, Tartaglia J, Shintani A, Currier J, Slike B, Crowe JE, Marovich M, Spearman P. Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses. J Virol. 2005 May; 79(9):5537-47. PMID: 15827168; PMCID: PMC1082749.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    406. Bentzen EL, House F, Utley TJ, Crowe JE, Wright DW. Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes. Nano Lett. 2005 Apr; 5(4):591-5. PMID: 15826092.
      Citations: 26     Fields:    Translation:HumansCells
    407. Kallewaard NL, Bowen AL, Lafleur BJ, Greenberg HB, Crowe JE, Weitkamp JH. VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7. J Immunol. 2005 Mar 15; 174(6):3454-60. PMID: 15749880.
      Citations: 25     Fields:    Translation:HumansCells
    408. Rock MT, Yoder SM, Wright PF, Talbot TR, Edwards KM, Crowe JE. Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization. J Immunol. 2005 Mar 15; 174(6):3757-64. PMID: 15749916.
      Citations: 25     Fields:    Translation:HumansCells
    409. Tai JH, Williams JV, Edwards KM, Wright PF, Crowe JE, Dermody TS. Prevalence of reovirus-specific antibodies in young children in Nashville, Tennessee. J Infect Dis. 2005 Apr 15; 191(8):1221-4. PMID: 15776366; PMCID: PMC7109872.
      Citations: 59     Fields:    Translation:HumansCells
    410. Shaklee JF, Talbot TR, Muldowney JA, Vaughan DE, Butler J, House F, Crowe JE, Smith LH, Edwards KM. Smallpox vaccination does not elevate systemic levels of prothrombotic proteins associated with ischemic cardiac events. J Infect Dis. 2005 Mar 01; 191(5):724-30. PMID: 15688286.
      Citations: 2     Fields:    Translation:Humans
    411. Kallewaard NL, Bowen AL, Crowe JE. Cooperativity of actin and microtubule elements during replication of respiratory syncytial virus. Virology. 2005 Jan 05; 331(1):73-81. PMID: 15582654.
      Citations: 55     Fields:    Translation:HumansCells
    412. Crowe JE. Human metapneumovirus as a major cause of human respiratory tract disease. Pediatr Infect Dis J. 2004 Nov; 23(11 Suppl):S215-21. PMID: 15577576.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    413. Talbot TR, Stapleton JT, Brady RC, Winokur PL, Bernstein DI, Germanson T, Yoder SM, Rock MT, Crowe JE, Edwards KM. Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial. JAMA. 2004 Sep 08; 292(10):1205-12. PMID: 15353533.
      Citations: 15     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    414. Rock MT, Yoder SM, Talbot TR, Edwards KM, Crowe JE. Adverse events after smallpox immunizations are associated with alterations in systemic cytokine levels. J Infect Dis. 2004 Apr 15; 189(8):1401-10. PMID: 15073677.
      Citations: 26     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    415. Suara RO, Crowe JE. Effect of zinc salts on respiratory syncytial virus replication. Antimicrob Agents Chemother. 2004 Mar; 48(3):783-90. PMID: 14982765; PMCID: PMC353050.
      Citations: 66     Fields:    Translation:HumansCells
    416. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingsterhaus JM, Edwards KM, Wright PF, Crowe JE. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med. 2004 Jan 29; 350(5):443-50. PMID: 14749452; PMCID: PMC1831873.
      Citations: 384     Fields:    Translation:HumansCells
    417. Brock SC, Goldenring JR, Crowe JE. Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15143-8. PMID: 14630951; PMCID: PMC299925.
      Citations: 63     Fields:    Translation:AnimalsCells
    418. Kallewaard N, Kusuhara K, Bures E, Williams JV, LaFleur B, Greenberg HB, Crowe JE, Weitkamp JH. Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol. 2003 Nov 01; 171(9):4680-8. PMID: 14568943.
      Citations: 34     Fields:    Translation:HumansCells
    419. Halasa NB, Whitlock JA, McCurley TL, Smith JA, Zhu Q, Ochs H, Dermody TS, Crowe JE. Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein. Clin Infect Dis. 2003 Nov 15; 37(10):e136-41. PMID: 14583885.
      Citations: 6     Fields:    Translation:HumansCells
    420. Barrett S, Collins M, Kenny C, Ryan E, Keane CO, Crowe J. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. J Med Virol. 2003 Oct; 71(2):212-8. PMID: 12938195.
      Citations:    
    421. Venter M, Rock M, Puren AJ, Tiemessen CT, Crowe JE. Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol. 2003 Jul; 77(13):7319-29. PMID: 12805430; PMCID: PMC164818.
      Citations: 21     Fields:    Translation:HumansCellsPHPublic Health
    422. Crowe JE, Williams JV. Immunology of viral respiratory tract infection in infancy. Paediatr Respir Rev. 2003 Jun; 4(2):112-9. PMID: 12758048.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    423. Crowe JE, Sannella EC, Pfeiffer S, Zorn GL, Azimzadeh A, Newman R, Miller GG, Pierson RN. CD154 regulates primate humoral immunity to influenza. Am J Transplant. 2003 Jun; 3(6):680-8. PMID: 12780559.
      Citations: 6     Fields:    Translation:Animals
    424. Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE, Weitkamp JH. Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods. 2003 Apr 01; 275(1-2):223-37. PMID: 12667686.
      Citations: 33     Fields:    Translation:HumansCells
    425. Rock MT, Crowe JE. Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology. 2003 Apr; 108(4):474-80. PMID: 12667209; PMCID: PMC1782928.
      Citations: 26     Fields:    Translation:HumansCells
    426. Coughlan B, Sheehan J, Carr A, Crowe J. An investigation of the psychosocial impact of a Compensation Tribunal on women with latrogenic hepatitis C infection. Ir Med J. 2003 Mar; 96(3):73-7. PMID: 12722782.
      Citations: 1     Fields:    Translation:Humans
    427. Bruzzi JF, O'Connell MJ, Thakore H, O'Keane C, Crowe J, Murray JG. Transjugular liver biopsy: assessment of safety and efficacy of the Quick-Core biopsy needle. Abdom Imaging. 2002 Nov-Dec; 27(6):711-5. PMID: 12395261.
      Citations: 12     Fields:    Translation:Humans
    428. Brock SC, McGraw PA, Wright PF, Crowe JE. The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun. 2002 Sep; 70(9):5091-5. PMID: 12183558; PMCID: PMC128237.
      Citations: 15     Fields:    Translation:HumansCells
    429. Peters TR, Jennings MT, Crowe JE. Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol. 2002 Mar; 19(2):141-3. PMID: 11881789.
      Citations:    Fields:    Translation:Humans
    430. Crowe JE. Respiratory syncytial virus vaccine development. Vaccine. 2001 Oct 15; 20 Suppl 1:S32-7. PMID: 11587807.
      Citations: 21     Fields:    Translation:HumansAnimals
    431. Crowe JE. Influence of maternal antibodies on neonatal immunization against respiratory viruses. Clin Infect Dis. 2001 Nov 15; 33(10):1720-7. PMID: 11595986.
      Citations: 33     Fields:    Translation:HumansCellsPHPublic Health
    432. Crowe JE, Firestone CY, Murphy BR. Passively acquired antibodies suppress humoral but not cell-mediated immunity in mice immunized with live attenuated respiratory syncytial virus vaccines. J Immunol. 2001 Oct 01; 167(7):3910-8. PMID: 11564809.
      Citations: 49     Fields:    Translation:AnimalsCells
    433. Weitkamp JH, Crowe JE. Blood donor leukocyte reduction filters as a source of human B lymphocytes. Biotechniques. 2001 Sep; 31(3):464, 466. PMID: 11570486.
      Citations: 6     Fields:    Translation:HumansCells
    434. Barrett S, Goh J, Coughlan B, Ryan E, Stewart S, Cockram A, O'Keane JC, Crowe J. The natural course of hepatitis C virus infection after 22 years in a unique homogenous cohort: spontaneous viral clearance and chronic HCV infection. Gut. 2001 Sep; 49(3):423-30. PMID: 11511566; PMCID: PMC1728443.
      Citations: 39     Fields:    Translation:HumansCells
    435. Crowe JE, Suara RO, Brock S, Kallewaard N, House F, Weitkamp JH. Genetic and structural determinants of virus neutralizing antibodies. Immunol Res. 2001; 23(2-3):135-45. PMID: 11444379.
      Citations: 6     Fields:    Translation:HumansCells
    436. Pierson RN, Crowe JE, Pfeiffer S, Atkinson J, Azimzadeh A, Miller GG. CD40-ligand in primate cardiac allograft and viral immunity. Immunol Res. 2001; 23(2-3):253-62. PMID: 11444390.
      Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    437. Peters M, Crowe J, Piéri JF, Quartero H, Hayes-Gill B, James D, Stinstra J, Shakespeare S, Pi?ri JF. Monitoring the fetal heart non-invasively: a review of methods. J Perinat Med. 2001; 29(5):408-16. PMID: 11723842.
      Citations: 35     Fields:    Translation:Humans
    438. Weitkamp JH, Tang YW, Haas DW, Midha NK, Crowe JE. Recurrent Achromobacter xylosoxidans bacteremia associated with persistent lymph node infection in a patient with hyper-immunoglobulin M syndrome. Clin Infect Dis. 2000 Nov; 31(5):1183-7. PMID: 11073750.
      Citations: 20     Fields:    Translation:HumansCells
    439. Peters TR, Brumbaugh DE, Lawton AR, Crowe JE. Recurrent pneumococcal arthritis as the presenting manifestation of X-linked agammaglobulinemia. Clin Infect Dis. 2000 Nov; 31(5):1287-8. PMID: 11073766.
      Citations: 4     Fields:    Translation:HumansCells
    440. Wright PF, Karron RA, Belshe RB, Thompson J, Crowe JE, Boyce TG, Halburnt LL, Reed GW, Whitehead SS, Anderson EL, Wittek AE, Casey R, Eichelberger M, Thumar B, Randolph VB, Udem SA, Chanock RM, Murphy BR. Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy. J Infect Dis. 2000 Nov; 182(5):1331-42. PMID: 11010838.
      Citations: 119     Fields:    Translation:HumansCellsPHPublic Health
    441. Cooper HA, Crowe J, Butler MG. SPONASTRIME dysplasia: report of an 11-year-old boy and review of the literature. Am J Med Genet. 2000 May 01; 92(1):33-9. PMID: 10797420; PMCID: PMC5237388.
      Citations: 4     Fields:    Translation:Humans
    442. Pastey MK, Gower TL, Spearman PW, Crowe JE, Graham BS. A RhoA-derived peptide inhibits syncytium formation induced by respiratory syncytial virus and parainfluenza virus type 3. Nat Med. 2000 Jan; 6(1):35-40. PMID: 10613821; PMCID: PMC7095870.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    443. Hegamin-Younger C, Piven ML, Buckwalter KC, Schacht E, Brems CS, Hradek E, Keen P, Morris W, Crowe JE. Use of the Iowa Self-Assessment Inventory with older hospitalized patients. J Gerontol Nurs. 1999 Nov; 25(11):44-9. PMID: 10776162.
      Citations:    Fields:    Translation:HumansPHPublic Health
    444. Fisher RG, Crowe JE, Johnson TR, Tang YW, Graham BS. Passive IgA monoclonal antibody is no more effective than IgG at protecting mice from mucosal challenge with respiratory syncytial virus. J Infect Dis. 1999 Oct; 180(4):1324-7. PMID: 10479165.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    445. Pastey MK, Crowe JE, Graham BS. RhoA interacts with the fusion glycoprotein of respiratory syncytial virus and facilitates virus-induced syncytium formation. J Virol. 1999 Sep; 73(9):7262-70. PMID: 10438814; PMCID: PMC104251.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    446. Goh J, Coughlan B, Quinn J, O'Keane JC, Crowe J. Fatigue does not correlate with the degree of hepatitis or the presence of autoimmune disorders in chronic hepatitis C infection. Eur J Gastroenterol Hepatol. 1999 Aug; 11(8):833-8. PMID: 10514113.
      Citations: 25     Translation:HumansCells
    447. Barrett S, Ryan E, Crowe J. Association of the HLA-DRB1*01 allele with spontaneous viral clearance in an Irish cohort infected with hepatitis C virus via contaminated anti-D immunoglobulin. J Hepatol. 1999 Jun; 30(6):979-83. PMID: 10406173.
      Citations: 21     Fields:    Translation:HumansCellsPHPublic Health
    448. Sakurai H, Williamson RA, Crowe JE, Beeler JA, Poignard P, Bastidas RB, Chanock RM, Burton DR. Human antibody responses to mature and immature forms of viral envelope in respiratory syncytial virus infection: significance for subunit vaccines. J Virol. 1999 Apr; 73(4):2956-62. PMID: 10074145; PMCID: PMC104055.
      Citations: 21     Fields:    Translation:HumansCells
    449. Whitehead SS, Firestone CY, Karron RA, Crowe JE, Elkins WR, Collins PL, Murphy BR. Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity. J Virol. 1999 Feb; 73(2):871-7. PMID: 9882287; PMCID: PMC103906.
      Citations: 27     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    450. Crowe JE, Randolph V, Murphy BR. The live attenuated subgroup B respiratory syncytial virus vaccine candidate RSV 2B33F is attenuated and immunogenic in chimpanzees, but exhibits partial loss of the ts phenotype following replication in vivo. Virus Res. 1999 Jan; 59(1):13-22. PMID: 10854162.
      Citations: 4     Fields:    Translation:AnimalsCells
    451. Clarke G, Ryan E, Crowe J, O'Keane JC, MacMathúna P, MacMath?na P. Immunohistochemical detection of mutant p53 protein in regional lymph nodes is associated with adverse outcome in stage II colorectal cancer. Eur J Histochem. 1999; 43(4):311-6. PMID: 10682269.
      Citations: 4     Fields:    Translation:Humans
    452. Crowe JE. Host responses to respiratory virus infection and immunization. Curr Top Microbiol Immunol. 1999; 236:191-214. PMID: 9893361.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    453. Crowe JE, Firestone CY, Crim R, Beeler JA, Coelingh KL, Barbas CF, Burton DR, Chanock RM, Murphy BR. Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein. Virology. 1998 Dec 20; 252(2):373-5. PMID: 9878616.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    454. Crowe JE. Immune responses of infants to infection with respiratory viruses and live attenuated respiratory virus candidate vaccines. Vaccine. 1998 Aug-Sep; 16(14-15):1423-32. PMID: 9711783.
      Citations: 8     Fields:    Translation:HumansCells
    455. Crowe JE, Gilmour PS, Murphy BR, Chanock RM, Duan L, Pomerantz RJ, Pilkington GR. Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivo. J Infect Dis. 1998 Apr; 177(4):1073-6. PMID: 9534985.
      Citations: 9     Fields:    Translation:AnimalsCells
    456. Karron RA, Wright PF, Crowe JE, Clements-Mann ML, Thompson J, Makhene M, Casey R, Murphy BR. Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children. J Infect Dis. 1997 Dec; 176(6):1428-36. PMID: 9395351.
      Citations: 67     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    457. Juhasz K, Whitehead SS, Bui PT, Biggs JM, Crowe JE, Boulanger CA, Collins PL, Murphy BR. The temperature-sensitive (ts) phenotype of a cold-passaged (cp) live attenuated respiratory syncytial virus vaccine candidate, designated cpts530, results from a single amino acid substitution in the L protein. J Virol. 1997 Aug; 71(8):5814-9. PMID: 9223470; PMCID: PMC191836.
      Citations: 20     Fields:    Translation:Cells
    458. Clarke G, MacMathuna P, Fenlon H, Callagy G, O'Keane JC, Carney D, Crowe J. Primary hepatic lymphoma in a man with chronic hepatitis C. Eur J Gastroenterol Hepatol. 1997 Jan; 9(1):87-90. PMID: 9031906.
      Citations: 1     Translation:HumansCells
    459. Firestone CY, Whitehead SS, Collins PL, Murphy BR, Crowe JE. Nucleotide sequence analysis of the respiratory syncytial virus subgroup A cold-passaged (cp) temperature sensitive (ts) cpts-248/404 live attenuated virus vaccine candidate. Virology. 1996 Nov 15; 225(2):419-22. PMID: 8918930.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    460. Crowe JE, Bui PT, Firestone CY, Connors M, Elkins WR, Chanock RM, Murphy BR. Live subgroup B respiratory syncytial virus vaccines that are attenuated, genetically stable, and immunogenic in rodents and nonhuman primates. J Infect Dis. 1996 Apr; 173(4):829-39. PMID: 8603960.
      Citations: 22     Fields:    Translation:AnimalsCells
    461. Crowe J, Masone BS, Ribbe J. One-step purification of recombinant proteins with the 6xHis tag and Ni-NTA resin. Methods Mol Biol. 1996; 58:491-510. PMID: 8713899.
      Citations: 16     Fields:    Translation:Cells
    462. Crowe JE, Firestone CY, Whitehead SS, Collins PL, Murphy BR. Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respiratory syncytial virus vaccine candidate results from the acquisition of a single mutation in the polymerase (L) gene. Virus Genes. 1996; 13(3):269-73. PMID: 9035372.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    463. Crowe JE, Bui PT, Siber GR, Elkins WR, Chanock RM, Murphy BR. Cold-passaged, temperature-sensitive mutants of human respiratory syncytial virus (RSV) are highly attenuated, immunogenic, and protective in seronegative chimpanzees, even when RSV antibodies are infused shortly before immunization. Vaccine. 1995 Jun; 13(9):847-55. PMID: 7483808.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    464. Connors M, Crowe JE, Firestone CY, Murphy BR, Collins PL. A cold-passaged, attenuated strain of human respiratory syncytial virus contains mutations in the F and L genes. Virology. 1995 Apr 20; 208(2):478-84. PMID: 7747420.
      Citations: 20     Fields:    Translation:HumansCells
    465. Hsu KH, Crowe JE, Lubeck MD, Davis AR, Hung PP, Chanock RM, Murphy BR. Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus. Vaccine. 1995 Apr; 13(5):509-15. PMID: 7543716.
      Citations: 4     Fields:    Translation:AnimalsCells
    466. Crowe JE. Current approaches to the development of vaccines against disease caused by respiratory syncytial virus (RSV) and parainfluenza virus (PIV). A meeting report of the WHO Programme for Vaccine Development. Vaccine. 1995 Mar; 13(4):415-21. PMID: 7793140.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    467. Kulkarni AB, Collins PL, Bacik I, Yewdell JW, Bennink JR, Crowe JE, Murphy BR. Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia virus. J Virol. 1995 Feb; 69(2):1261-4. PMID: 7815502; PMCID: PMC188700.
      Citations: 38     Fields:    Translation:AnimalsCellsPHPublic Health
    468. Crowe JE, Cheung PY, Wallace EF, Chanock RM, Larrick JW, Murphy BR, Fry K. Isolation and characterization of a chimpanzee monoclonal antibody to the G glycoprotein of human respiratory syncytial virus. Clin Diagn Lab Immunol. 1994 Nov; 1(6):701-6. PMID: 8556524; PMCID: PMC368396.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    469. Crowe JE, Bui PT, Davis AR, Chanock RM, Murphy BR. A further attenuated derivative of a cold-passaged temperature-sensitive mutant of human respiratory syncytial virus retains immunogenicity and protective efficacy against wild-type challenge in seronegative chimpanzees. Vaccine. 1994 Jul; 12(9):783-90. PMID: 7975856.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    470. Crowe JE, Bui PT, London WT, Davis AR, Hung PP, Chanock RM, Murphy BR. Satisfactorily attenuated and protective mutants derived from a partially attenuated cold-passaged respiratory syncytial virus mutant by introduction of additional attenuating mutations during chemical mutagenesis. Vaccine. 1994 Jun; 12(8):691-9. PMID: 8091846.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    471. Murphy BR, Hall SL, Kulkarni AB, Crowe JE, Collins PL, Connors M, Karron RA, Chanock RM. An update on approaches to the development of respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) vaccines. Virus Res. 1994 Apr; 32(1):13-36. PMID: 8030364.
      Citations: 38     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    472. Crowe JE, Murphy BR, Chanock RM, Williamson RA, Barbas CF, Burton DR. Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1386-90. PMID: 8108420; PMCID: PMC43163.
      Citations: 30     Fields:    Translation:HumansAnimals
    473. Crowe J, Döbeli H, Gentz R, Hochuli E, Stüber D, Henco K, D?beli H, St?ber D. 6xHis-Ni-NTA chromatography as a superior technique in recombinant protein expression/purification. Methods Mol Biol. 1994; 31:371-87. PMID: 7921034.
      Citations: 67     Fields:    Translation:Cells
    474. Crowe JE, Collins PL, London WT, Chanock RM, Murphy BR. A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respiratory syncytial virus (RSV) temperature-sensitive mutant vaccines and vaccinia virus recombinants that express the surface glycoproteins of RSV. Vaccine. 1993 Nov; 11(14):1395-404. PMID: 8310760.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    475. Chanock RM, Crowe JE, Murphy BR, Burton DR. Human monoclonal antibody Fab fragments cloned from combinatorial libraries: potential usefulness in prevention and/or treatment of major human viral diseases. Infect Agents Dis. 1993 Jun; 2(3):118-31. PMID: 8173784.
      Citations: 14     Fields:    Translation:HumansCells
    476. Engeler CE, Olson PN, Engeler CM, Carpenter BL, Crowe JE, Day DL, Hertz MI, Bolman RM. Shifting pneumothorax after heart-lung transplantation. Radiology. 1992 Dec; 185(3):715-7. PMID: 1438751.
      Citations: 2     Fields:    Translation:Humans
    477. Barbas CF, Crowe JE, Cababa D, Jones TM, Zebedee SL, Murphy BR, Chanock RM, Burton DR. Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity. Proc Natl Acad Sci U S A. 1992 Nov 01; 89(21):10164-8. PMID: 1279672; PMCID: PMC50298.
      Citations: 49     Fields:    Translation:HumansCells
    478. Franceschi D, Crowe J, Zollinger R, Duchesneau R, Shenk R, Stefanek G, Shuck JM. Biopsy of the breast for mammographically detected lesions. Surg Gynecol Obstet. 1990 Dec; 171(6):449-55. PMID: 2244276.
      Citations: 6     Fields:    Translation:Humans
    479. Franceschi D, Crowe J, Zollinger R, Duchesneau R, Shenk R, Stefanek G, Shuck JM. Breast biopsy for calcifications in nonpalpable breast lesions. A prospective study. Arch Surg. 1990 Feb; 125(2):170-3. PMID: 2154171.
      Citations: 5     Fields:    Translation:Humans
    480. Bulger K, Griffin M, Dervan P, Lennon J, Crowe J. Coeliac disease in association with inflammatory bowel disease. Postgrad Med J. 1988 Apr; 64(750):336. PMID: 3186585; PMCID: PMC2428489.
      Citations: 6     Fields:    Translation:Humans
    481. Bulger K, Griffin M, O'Brien M, Crowe J. Lymphoma in the mesenteric lymph node cavitation syndrome. Gastroenterology. 1988 Feb; 94(2):553. PMID: 3335328.
      Citations: 1     Fields:    Translation:Humans
    482. Christensen E, Neuberger J, Crowe J, Portmann B, Williams R, Altman DG, Popper H, Doniach D, Ranek L, Tygstrup N. Azathioprine and prognosis in primary biliary cirrhosis. Gastroenterology. 1986 Feb; 90(2):508-9. PMID: 3510149.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    483. Christensen E, Neuberger J, Crowe J, Altman DG, Popper H, Portmann B, Doniach D, Ranek L, Tygstrup N, Williams R. Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial. Gastroenterology. 1985 Nov; 89(5):1084-91. PMID: 3899841.
      Citations: 58     Fields:    Translation:HumansCTClinical Trials
    484. Shanahan F, Crowe J. Cimetidine and the control of pain in chronic relapsing pancreatitis. N Engl J Med. 1981 Sep 10; 305(11):644. PMID: 7266594.
      Citations:    Fields:    Translation:Humans
    485. Sumner TE, Crowe JE, Klein A, McKone RC, Weaver RL. Intrapericardial teratoma in infancy. Pediatr Radiol. 1980 Sep; 10(1):51-3. PMID: 7422393.
      Citations: 5     Fields:    Translation:Humans
    486. Crowe J, Christensen E, Smith M, Cochrane M, Ranek L, Watkinson G, Doniach D, Popper H, Tygstrup N, Williams R. Azathioprine in primary biliary cirrhosis: a preliminary report of an international trial. Gastroenterology. 1980 May; 78(5 Pt 1):1005-10. PMID: 6991353.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    487. Sumner TE, Crowe JE, Parker MD, White JP. Solitary spinal metastasis from Wilms' tumor. Pediatr Radiol. 1980 Apr; 9(3):175-6. PMID: 6248834.
      Citations: 3     Fields:    Translation:Humans
    488. Christensen E, Crowe J, Doniach D, Popper H, Ranek L, Rodés J, Tygstrup N, Williams R, Rod?s J. Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients. Gastroenterology. 1980 Feb; 78(2):236-46. PMID: 7350046.
      Citations: 42     Fields:    Translation:HumansCTClinical Trials
    489. Sumner TE, Phelps CR, Crowe JE, Poolos SP, Shaffner LD. Pulmonary blastoma in a child. AJR Am J Roentgenol. 1979 Jul; 133(1):147-8. PMID: 110053.
      Citations: 3     Fields:    Translation:Humans
    490. Brasch RC, Royal S, Ammann AJ, Crowe J. Pseudolymphoma in two immunodeficient children. AJR Am J Roentgenol. 1979 May; 132(5):844-7. PMID: 107763.
      Citations: 3     Fields:    Translation:Humans
    491. Sumner T, Friedland GW, Parker B, Thomas J, Crowe J, Resnick M. Preoperative diagnosis of unilateral multicystic kidney with hydropelvis. Urology. 1978 May; 11(5):519-22. PMID: 675913.
      Citations: 1     Fields:    Translation:Humans
    492. Crowe JE, Sumner TE. Combined esophageal and duodenal atresia without tracheoesophageal fustula: characteristic radiographic changes. AJR Am J Roentgenol. 1978 Jan; 130(1):167-8. PMID: 413406.
      Citations:    Fields:    Translation:Humans
    493. Swischuk LE, Crowe JE, Mewborne EJ. Large vein of Galen aneurysms in the neonate. A constellation of diagnostic chest and neck radiologic findings. Pediatr Radiol. 1977 Jul 25; 6(1):4-9. PMID: 142234.
      Citations: 3     Fields:    Translation:Humans
    494. Crowe JE, Swischuk LE. Acute bowing fractures of the forearm in children: a frequently missed injury. AJR Am J Roentgenol. 1977 Jun; 128(6):981-4. PMID: 414566.
      Citations: 15     Fields:    Translation:Humans
    495. Crowe JE. Removal of blunt esophageal foreign bodies: Foley catheter technique. N C Med J. 1976 Aug; 37(8):431-2. PMID: 1067479.
      Citations:    Fields:    Translation:Humans
    496. Chang SH, Morrison L, Shaffner L, Crowe JE. Intrathoracic gastrogenic cysts and hemoptysis. J Pediatr. 1976 Apr; 88(4 Pt 1):594-6. PMID: 1255319.
      Citations:    Fields:    Translation:Humans
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