"Cell Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
| Descriptor ID |
D002454
|
| MeSH Number(s) |
G04.152
|
| Concept/Terms |
Cell Differentiation- Cell Differentiation
- Differentiation, Cell
- Cell Differentiations
- Differentiations, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Differentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Differentiation".
This graph shows the total number of publications written about "Cell Differentiation" by people in this website by year, and whether "Cell Differentiation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 11 | 13 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 16 | 16 |
| 1999 | 0 | 10 | 10 |
| 2000 | 1 | 22 | 23 |
| 2001 | 3 | 25 | 28 |
| 2002 | 6 | 28 | 34 |
| 2003 | 4 | 30 | 34 |
| 2004 | 14 | 32 | 46 |
| 2005 | 10 | 24 | 34 |
| 2006 | 13 | 33 | 46 |
| 2007 | 8 | 40 | 48 |
| 2008 | 12 | 29 | 41 |
| 2009 | 16 | 31 | 47 |
| 2010 | 16 | 40 | 56 |
| 2011 | 26 | 41 | 67 |
| 2012 | 17 | 39 | 56 |
| 2013 | 25 | 60 | 85 |
| 2014 | 13 | 40 | 53 |
| 2015 | 20 | 60 | 80 |
| 2016 | 10 | 35 | 45 |
| 2017 | 18 | 44 | 62 |
| 2018 | 16 | 44 | 60 |
| 2019 | 16 | 34 | 50 |
| 2020 | 12 | 40 | 52 |
| 2021 | 14 | 42 | 56 |
| 2022 | 4 | 36 | 40 |
| 2023 | 0 | 38 | 38 |
| 2024 | 11 | 37 | 48 |
| 2025 | 12 | 30 | 42 |
| 2026 | 5 | 9 | 14 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cell Differentiation" by people in Profiles.
-
Mechanisms coordinating exit from the stem cell state in mammals. Genes Dev. 2026 07 01; 40(13-14):982-1011.
-
Coexpression of IL15 Promotes Effector Differentiation and Sustained Proliferative Capacity in ALPPL2-Specific Human CAR T Cells. Cancer Immunol Res. 2026 Jun 02; 14(6):933-943.
-
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs. Nat Genet. 2026 Jun; 58(6):1368-1382.
-
Targeting the IRE1a-XBP1 signaling axis impairs tumor growth and promotes myogenic differentiation in rhabdomyosarcoma. Commun Biol. 2026 May 06; 9(1).
-
Disordered differentiation and cellular senescence in pediatric Hodgkin Reed-Sternberg cells. Blood Adv. 2026 Apr 28; 10(8):2711-2726.
-
NOTCH1 acts as a tumor suppressor that induces early differentiation in head and neck cancer. JCI Insight. 2026 Jun 08; 11(11).
-
TAK1 is a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma. Oncogene. 2026 May; 45(18):1714-1728.
-
Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model. Nat Commun. 2026 Apr 01; 17(1).
-
Dominant clones leverage developmental epigenomic states to drive ependymoma. Nature. 2026 04; 652(8111):1027-1037.
-
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma. Nature. 2026 04; 652(8110):763-773.