"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 3 | 5 |
| 2005 | 2 | 2 | 4 |
| 2006 | 3 | 1 | 4 |
| 2007 | 3 | 4 | 7 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 3 | 4 |
| 2010 | 2 | 5 | 7 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 3 | 7 | 10 |
| 2015 | 0 | 5 | 5 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 3 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 4 | 2 | 6 |
| 2020 | 5 | 2 | 7 |
| 2021 | 5 | 3 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 3 | 3 | 6 |
| 2024 | 3 | 2 | 5 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease. Arterioscler Thromb Vasc Biol. 2025 Mar; 45(3):372-385.
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Placentas From SARS-CoV-2 Infection During Pregnancy Exhibit Foci of Oxidative Stress and DNA Damage. Am J Reprod Immunol. 2025 Jan; 93(1):e70034.
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Senescence Biomarkers and Trajectories of Frailty and Physical Function After Kidney Transplantation. Clin Transplant. 2024 Nov; 38(11):e70022.
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CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia. Blood. 2024 09 12; 144(11):1168-1182.
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Single-cell total-RNA profiling unveils regulatory hubs of transcription factors. Nat Commun. 2024 Jul 15; 15(1):5941.
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TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25; 187(15):4030-4042.e13.
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IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy. Clin Cancer Res. 2024 Jun 03; 30(11):2558-2570.
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Human platelet lysate enhances in vivo activity of CAR-Vd2 T cells by reducing cellular senescence and apoptosis. Cytotherapy. 2024 Aug; 26(8):858-868.
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Tissue mosaicism following stem cell aging: blood as an exemplar. Nat Aging. 2024 Mar; 4(3):295-308.
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D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1?-driven pyroptotic uroepithelial cell shedding in the murine bladder. Dev Cell. 2024 Jan 08; 59(1):33-47.e5.