Cell Transdifferentiation
"Cell Transdifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring phenomenon where terminally differentiated cells dedifferentiate to the point where they can switch CELL LINEAGES. The cells then differentiate into other cell types.
| Descriptor ID |
D054338
|
| MeSH Number(s) |
G04.356
|
| Concept/Terms |
Cell Transdifferentiation- Cell Transdifferentiation
- Cell Transdifferentiations
- Transdifferentiations, Cell
- Transdifferentiation, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Transdifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Transdifferentiation".
This graph shows the total number of publications written about "Cell Transdifferentiation" by people in this website by year, and whether "Cell Transdifferentiation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 4 | 1 | 5 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 4 | 5 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cell Transdifferentiation" by people in Profiles.
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Macrophages in the infarcted heart acquire a fibrogenic phenotype, expressing matricellular proteins, but do not undergo fibroblast conversion. J Mol Cell Cardiol. 2024 Nov; 196:152-167.
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The clinical utility and diagnostic implementation of human subject cell transdifferentiation followed by RNA sequencing. Am J Hum Genet. 2024 05 02; 111(5):841-862.
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Recent advances and future prospects in direct cardiac reprogramming. Nat Cardiovasc Res. 2023 12; 2(12):1148-1158.
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Active DNA demethylation promotes cell fate specification and the DNA damage response. Science. 2022 12 02; 378(6623):983-989.
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Hippo Pathway Effector Tead1 Induces Cardiac Fibroblast to Cardiomyocyte Reprogramming. J Am Heart Assoc. 2021 12 21; 10(24):e022659.
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Fibroblast transition to an endothelial "trans" state improves cell reprogramming efficiency. Sci Rep. 2021 11 19; 11(1):22605.
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Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Dev Cell. 2021 09 13; 56(17):2471-2485.e5.
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Glucagon blockade restores functional ?-cell mass in type 1 diabetic mice and enhances function of human islets. Proc Natl Acad Sci U S A. 2021 03 02; 118(9).
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From the archives of MD Anderson Cancer Center: A case of concurrent follicular lymphoma and Langerhans cell sarcoma with a review of the literature. Ann Diagn Pathol. 2021 Jun; 52:151720.
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Cellular plasticity at the nexus of development and disease. Development. 2021 02 05; 148(3).