Histiocytosis, Langerhans-Cell
"Histiocytosis, Langerhans-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
| Descriptor ID |
D006646
|
| MeSH Number(s) |
C08.381.483.375 C15.604.250.400
|
| Concept/Terms |
Histiocytosis, Langerhans-Cell- Histiocytosis, Langerhans-Cell
- Histiocytosis, Langerhans Cell
- Hand-Schueller-Christian Syndrome
- Hand Schueller Christian Syndrome
- Syndrome, Hand-Schueller-Christian
- Hand-Schüller-Christian Disease
- Disease, Hand-Schüller-Christian
- Hand Schüller Christian Disease
- Hand-Schüller-Christian Syndrome
- Hand Schüller Christian Syndrome
- Syndrome, Hand-Schüller-Christian
- Histiocytosis X
- Histiocytosis, Generalized
- Generalized Histiocytoses
- Generalized Histiocytosis
- Histiocytoses, Generalized
- Histiocytosis-X
- Langerhans Cell Histiocytosis
- Cell Histiocytoses, Langerhans
- Cell Histiocytosis, Langerhans
- Histiocytoses, Langerhans Cell
- Langerhans Cell Histiocytoses
- Langerhans-Cell Granulomatosis
- Granulomatosis, Langerhans-Cell
- Langerhans-Cell Histiocytosis
- Letterer-Siwe Disease
- Disease, Letterer-Siwe
- Letterer Siwe Disease
- Non-Lipid Reticuloendotheliosis
- Non Lipid Reticuloendotheliosis
- Non-Lipid Reticuloendothelioses
- Reticuloendothelioses, Non-Lipid
- Reticuloendotheliosis, Non-Lipid
- Schueller-Christian Disease
- Disease, Schueller-Christian
- Schueller Christian Disease
- Systemic Aleukemic Reticuloendotheliosis
- Aleukemic Reticuloendothelioses, Systemic
- Aleukemic Reticuloendotheliosis, Systemic
- Reticuloendothelioses, Systemic Aleukemic
- Reticuloendotheliosis, Systemic Aleukemic
- Systemic Aleukemic Reticuloendothelioses
- Type 2 Histiocytosis
- Histiocytoses, Type 2
- Histiocytosis, Type 2
- Type 2 Histiocytoses
- Langerhans Cell Granulomatosis
- Cell Granulomatoses, Langerhans
- Cell Granulomatosis, Langerhans
- Granulomatoses, Langerhans Cell
- Granulomatosis, Langerhans Cell
- Langerhans Cell Granulomatoses
- Hand-Schueller-Christian Disease
- Disease, Hand-Schueller-Christian
- Hand Schueller Christian Disease
Pulmonary Histiocytosis X- Pulmonary Histiocytosis X
- Histiocytosis X, Pulmonary
- Pulmonary Langerhans Cell Granulomatosis
- Langerhans Cell Granulomatosis, Pulmonary
|
Below are MeSH descriptors whose meaning is more general than "Histiocytosis, Langerhans-Cell".
Below are MeSH descriptors whose meaning is more specific than "Histiocytosis, Langerhans-Cell".
This graph shows the total number of publications written about "Histiocytosis, Langerhans-Cell" by people in this website by year, and whether "Histiocytosis, Langerhans-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 4 | 0 | 4 |
| 2004 | 4 | 0 | 4 |
| 2005 | 4 | 0 | 4 |
| 2007 | 4 | 0 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 4 | 0 | 4 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 5 | 0 | 5 |
| 2014 | 8 | 0 | 8 |
| 2015 | 8 | 0 | 8 |
| 2016 | 6 | 0 | 6 |
| 2017 | 7 | 0 | 7 |
| 2018 | 6 | 0 | 6 |
| 2019 | 3 | 1 | 4 |
| 2020 | 5 | 1 | 6 |
| 2021 | 7 | 0 | 7 |
| 2022 | 5 | 0 | 5 |
| 2023 | 6 | 0 | 6 |
| 2024 | 5 | 1 | 6 |
| 2025 | 3 | 0 | 3 |
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click here.
Below are the most recent publications written about "Histiocytosis, Langerhans-Cell" by people in Profiles.
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BRAF V600E-positive mononuclear cells in blood at diagnosis portend treatment failure and neurodegeneration in pediatric LCH. Blood. 2025 Jul 10; 146(2):206-218.
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Approach to the Patient: From Endocrinopathy to the Diagnosis of a Histiocytic Disorder. J Clin Endocrinol Metab. 2025 May 19; 110(6):1756-1766.
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Genomic Alterations in Langerhans Cell Histiocytosis. Hematol Oncol Clin North Am. 2025 Jun; 39(3):491-511.
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Langerhans cell histiocytosis in children born after assisted reproductive technology. Reprod Biomed Online. 2024 12; 49(6):104379.
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Mixed histiocytic disorders: Nature versus nurture? Br J Haematol. 2024 Jul; 205(1):20-21.
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Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures. Cancer. 2024 Jul 15; 130(14):2416-2439.
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From mutation to management: Advancing Langerhans cell histiocytosis treatment through combination therapies. Br J Haematol. 2024 May; 204(5):1588-1589.
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Clofarabine monotherapy in aggressive, relapsed and refractory Langerhans cell histiocytosis. Br J Haematol. 2024 May; 204(5):1888-1893.
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Clinical, radiological and molecular responses to combination chemotherapy with MAPK pathway inhibition in relapsed and refractory Langerhans cell histiocytosis. Br J Haematol. 2024 May; 204(5):1882-1887.
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Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders. Immunity. 2023 12 12; 56(12):2790-2802.e6.