"Langerhans Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
| Descriptor ID |
D007801
|
| MeSH Number(s) |
A11.066.270.500 A11.436.270.545 A15.382.066.270.500 A15.382.812.260.500
|
| Concept/Terms |
Langerhans Cells- Langerhans Cells
- Cells, Langerhans
- Epidermal Dendritic Cells
- Dendritic Cells, Epidermal
- Cell, Epidermal Dendritic
- Cells, Epidermal Dendritic
- Dendritic Cell, Epidermal
- Epidermal Dendritic Cell
Skin Dendritic Cells- Skin Dendritic Cells
- Cell, Skin Dendritic
- Cells, Skin Dendritic
- Dendritic Cell, Skin
- Skin Dendritic Cell
- Dendritic Cells, Skin
Dermal Dendritic Cells- Dermal Dendritic Cells
- Cell, Dermal Dendritic
- Cells, Dermal Dendritic
- Dendritic Cell, Dermal
- Dermal Dendritic Cell
- Dendritic Cells, Dermal
|
Below are MeSH descriptors whose meaning is more general than "Langerhans Cells".
Below are MeSH descriptors whose meaning is more specific than "Langerhans Cells".
This graph shows the total number of publications written about "Langerhans Cells" by people in this website by year, and whether "Langerhans Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Langerhans Cells" by people in Profiles.
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MUM1/IRF4 is Highly Expressed in Dermatopathic Lymphadenopathy: Potential Utility in Diagnosis and Differential Diagnosis. Am J Surg Pathol. 2022 11 01; 46(11):1514-1523.
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BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology. Nat Med. 2021 05; 27(5):851-861.
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From the archives of MD Anderson Cancer Center: A case of concurrent follicular lymphoma and Langerhans cell sarcoma with a review of the literature. Ann Diagn Pathol. 2021 Jun; 52:151720.
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BRAFV 600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell-like histiocytosis in immune-deficient mice. Blood Adv. 2020 10 13; 4(19):4912-4917.
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The coming of age of Langerhans cell histiocytosis. Nat Immunol. 2020 01; 21(1):1-7.
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RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. J Exp Med. 2018 01 02; 215(1):319-336.
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Langerhans Cell Histiocytosis: Emerging Insights and Clinical Implications. Oncology (Williston Park). 2016 Feb; 30(2):122-32, 139.
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A case of indeterminate dendritic cell tumor presenting with leonine facies. J Cutan Pathol. 2016 Feb; 43(2):158-63.
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Histologic patterns of thymic involvement in Langerhans cell proliferations: a clinicopathologic study and review of the literature. Pediatr Dev Pathol. 2015 Mar-Apr; 18(2):127-38.
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Progress in understanding the pathogenesis of Langerhans cell histiocytosis: back to Histiocytosis X? Br J Haematol. 2015 Apr; 169(1):3-13.