"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
| Descriptor ID |
D000938
|
| MeSH Number(s) |
A11.066 A15.382.066
|
| Concept/Terms |
Antigen-Presenting Cells- Antigen-Presenting Cells
- Antigen Presenting Cells
- Antigen-Presenting Cell
- Cell, Antigen-Presenting
- Cells, Antigen-Presenting
- Accessory Cells, Immunologic
- Immunologic Accessory Cells
- Cells, Immunologic Accessory
- Immunologic Accessory Cell
- Accessory Cell, Immunologic
- Cell, Immunologic Accessory
|
Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".
Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".
This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 3 | 4 |
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 3 | 7 | 10 |
| 2005 | 0 | 1 | 1 |
| 2006 | 4 | 4 | 8 |
| 2007 | 4 | 2 | 6 |
| 2008 | 3 | 1 | 4 |
| 2009 | 2 | 4 | 6 |
| 2010 | 3 | 5 | 8 |
| 2011 | 3 | 3 | 6 |
| 2012 | 2 | 9 | 11 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 3 | 5 |
| 2015 | 0 | 3 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 3 | 4 |
| 2019 | 3 | 3 | 6 |
| 2020 | 0 | 4 | 4 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.
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Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma. Front Immunol. 2023; 14:1295218.
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Central tolerance is impaired in the middle-aged thymic environment. Aging Cell. 2022 06; 21(6):e13624.
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Age-Related Changes in Thymic Central Tolerance. Front Immunol. 2021; 12:676236.
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Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity. J Biol Chem. 2021 Jan-Jun; 296:100523.
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GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells. Front Immunol. 2021; 12:626098.
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IL-7 During Antigenic Stimulation Using Allogeneic Dendritic Cells Promotes Expansion of CD45RA-CD62L+CD4+ Invariant NKT Cells With Th-2 Biased Cytokine Production Profile. Front Immunol. 2020; 11:567406.
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Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer. JCI Insight. 2020 06 18; 5(12).
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ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids. EMBO Rep. 2020 06 04; 21(6):e48927.
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Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma. Cancer Discov. 2020 03; 10(3):440-459.
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Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. ACS Nano. 2019 10 22; 13(10):10939-10960.