Anti-Glomerular Basement Membrane Disease
"Anti-Glomerular Basement Membrane Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Descriptor ID |
D019867
|
| MeSH Number(s) |
C08.381.483.156 C12.777.419.570.363.304 C13.351.968.419.570.363.304 C20.111.190
|
| Concept/Terms |
Anti-Glomerular Basement Membrane Disease- Anti-Glomerular Basement Membrane Disease
- Anti Glomerular Basement Membrane Disease
- Anti-GBM Disease
- Anti GBM Disease
- Lung Purpura with Nephritis
- Goodpasture's Syndrome
- Goodpastures Syndrome
- Syndrome, Goodpasture's
- Goodpasture Syndrome
- Syndrome, Goodpasture
|
Below are MeSH descriptors whose meaning is more general than "Anti-Glomerular Basement Membrane Disease".
Below are MeSH descriptors whose meaning is more specific than "Anti-Glomerular Basement Membrane Disease".
This graph shows the total number of publications written about "Anti-Glomerular Basement Membrane Disease" by people in this website by year, and whether "Anti-Glomerular Basement Membrane Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 0 | 1 |
| 1996 | 5 | 0 | 5 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 4 | 0 | 4 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 0 | 3 |
| 2005 | 3 | 0 | 3 |
| 2007 | 2 | 0 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 1 | 2 |
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Below are the most recent publications written about "Anti-Glomerular Basement Membrane Disease" by people in Profiles.
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Kallikrein transduced mesenchymal stem cells protect against anti-GBM disease and lupus nephritis by ameliorating inflammation and oxidative stress. PLoS One. 2013; 8(7):e67790.
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The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis. Kidney Int. 2011 Sep; 80(6):601-11.
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Osteopontin overproduction is associated with progression of glomerular fibrosis in a rat model of anti-glomerular basement membrane glomerulonephritis. Am J Nephrol. 2010; 32(3):262-271.
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Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. J Am Soc Nephrol. 2010 Sep; 21(9):1445-55.
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Superoxide dismutase mimetic drug tempol aggravates anti-GBM antibody-induced glomerulonephritis in mice. Am J Physiol Renal Physiol. 2010 Aug; 299(2):F445-52.
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The tissue's the issue. Am J Med. 2010 May; 123(5):420-2.
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Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis. J Immunol. 2010 Feb 15; 184(4):2183-93.
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Urine proteome analysis in murine nephrotoxic serum nephritis. Am J Nephrol. 2009; 30(5):450-8.
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Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol. 2010 Feb; 298(2):F248-54.
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Anti-inflammatory and renal protective actions of stanniocalcin-1 in a model of anti-glomerular basement membrane glomerulonephritis. Am J Pathol. 2009 Apr; 174(4):1368-78.