Anti-Glomerular Basement Membrane Disease
"Anti-Glomerular Basement Membrane Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Descriptor ID |
D019867
|
| MeSH Number(s) |
C08.381.483.156 C12.777.419.570.363.304 C13.351.968.419.570.363.304 C20.111.190
|
| Concept/Terms |
Anti-Glomerular Basement Membrane Disease- Anti-Glomerular Basement Membrane Disease
- Anti Glomerular Basement Membrane Disease
- Anti-GBM Disease
- Anti GBM Disease
- Lung Purpura with Nephritis
- Goodpasture's Syndrome
- Goodpastures Syndrome
- Syndrome, Goodpasture's
- Goodpasture Syndrome
- Syndrome, Goodpasture
|
Below are MeSH descriptors whose meaning is more general than "Anti-Glomerular Basement Membrane Disease".
Below are MeSH descriptors whose meaning is more specific than "Anti-Glomerular Basement Membrane Disease".
This graph shows the total number of publications written about "Anti-Glomerular Basement Membrane Disease" by people in this website by year, and whether "Anti-Glomerular Basement Membrane Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
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Below are the most recent publications written about "Anti-Glomerular Basement Membrane Disease" by people in Profiles.
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Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. J Am Soc Nephrol. 2010 Sep; 21(9):1445-55.
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Urine proteome analysis in murine nephrotoxic serum nephritis. Am J Nephrol. 2009; 30(5):450-8.
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Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol. 2010 Feb; 298(2):F248-54.
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Anti-inflammatory and renal protective actions of stanniocalcin-1 in a model of anti-glomerular basement membrane glomerulonephritis. Am J Pathol. 2009 Apr; 174(4):1368-78.
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Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 2006 Mar 01; 107(5):1908-15.
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Nasal administration of recombinant rat alpha3(IV)NC1 prevents the development of experimental autoimmune glomerulonephritis in the WKY rat. J Am Soc Nephrol. 2005 May; 16(5):1350-9.
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An unusual case of pulmonary-renal syndrome associated with defects in type IV collagen composition and anti-glomerular basement membrane autoantibodies. Am J Kidney Dis. 2005 Apr; 45(4):743-8.
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Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease. Kidney Int. 2003 Nov; 64(5):1685-94.
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Antiglomerular basement membrane autoantibodies are nonpathogenic in Wegener's granulomatosis. Am J Med. 2003 Oct 01; 115(5):414-5.
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The importance of cell-mediated immunity in the course and severity of autoimmune anti-glomerular basement membrane disease in mice. FASEB J. 2003 May; 17(8):860-8.