Glomerulosclerosis, Focal Segmental
"Glomerulosclerosis, Focal Segmental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Descriptor ID |
D005923
|
| MeSH Number(s) |
C12.777.419.570.363.660 C13.351.968.419.570.363.640
|
| Concept/Terms |
Glomerulosclerosis, Focal Segmental- Glomerulosclerosis, Focal Segmental
- Segmental Glomerulosclerosis, Focal
- Glomerulosclerosis, Focal
- Focal Glomerulosclerosis
- Focal Segmental Glomerulosclerosis
- Glomerulonephritis, Focal Sclerosing
- Focal Sclerosing Glomerulonephritides
- Focal Sclerosing Glomerulonephritis
- Glomerulonephritides, Focal Sclerosing
- Sclerosing Glomerulonephritides, Focal
- Sclerosing Glomerulonephritis, Focal
Hyalinosis, Segmental Glomerular- Hyalinosis, Segmental Glomerular
- Glomerular Hyalinosis, Segmental
- Segmental Glomerular Hyalinosis
- Hyalinosis, Segmental
- Segmental Hyalinosis
|
Below are MeSH descriptors whose meaning is more general than "Glomerulosclerosis, Focal Segmental".
Below are MeSH descriptors whose meaning is more specific than "Glomerulosclerosis, Focal Segmental".
This graph shows the total number of publications written about "Glomerulosclerosis, Focal Segmental" by people in this website by year, and whether "Glomerulosclerosis, Focal Segmental" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 3 | 0 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glomerulosclerosis, Focal Segmental" by people in Profiles.
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Report of the ASFA Apheresis Registry Study on Focal Segmental Glomerulosclerosis. J Clin Apher. 2025 Aug; 40(4):e70041.
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Post-transplant recurrence of focal segmental glomerular sclerosis: consensus statements. Kidney Int. 2024 03; 105(3):450-463.
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Rapid Progression of Focal Segmental Glomerulosclerosis in Patients with High-Risk APOL1 Genotypes. Clin J Am Soc Nephrol. 2023 03 01; 18(3):344-355.
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Protecting glomerulus: role of angiotensin-II type 2 receptor. Clin Sci (Lond). 2022 10 28; 136(20):1467-1470.
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Good outcomes after pediatric intraperitoneal kidney transplant. Pediatr Transplant. 2022 09; 26(6):e14294.
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De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis. Am J Hum Genet. 2021 02 04; 108(2):357-367.
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LDL-apheresis-induced remission of focal segmental glomerulosclerosis recurrence in pediatric renal transplant recipients. Pediatr Nephrol. 2019 11; 34(11):2343-2350.
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CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease. Am J Kidney Dis. 2019 02; 73(2):218-229.
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Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings. Pediatr Nephrol. 2018 10; 33(10):1773-1780.
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Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing. PLoS One. 2016; 11(12):e0167467.