Macrophage Activation Syndrome
"Macrophage Activation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of T-LYMPHOCYTES and MACROPHAGES. It is seen predominantly in children with systemic onset JUVENILE IDIOPATHIC ARTHRITIS.
| Descriptor ID |
D055501
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| MeSH Number(s) |
C20.683.515.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macrophage Activation Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation Syndrome".
This graph shows the total number of publications written about "Macrophage Activation Syndrome" by people in this website by year, and whether "Macrophage Activation Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 3 | 0 | 3 |
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Below are the most recent publications written about "Macrophage Activation Syndrome" by people in Profiles.
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Disease Course, Treatments, and Outcomes of Children With Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease. Arthritis Care Res (Hoboken). 2024 03; 76(3):328-339.
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The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). Ann Rheum Dis. 2023 10; 82(10):1271-1285.
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The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS). Arthritis Rheumatol. 2023 10; 75(10):1714-1732.
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Progressive, refractory macrophage activation syndrome as the initial presentation of anti-MDA5 antibody positive juvenile dermatomyositis: a case report and literature review. Pediatr Rheumatol Online J. 2022 Feb 22; 20(1):16.
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A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria. Front Immunol. 2021; 12:674808.
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A scoping review of the pathophysiology of COVID-19. Int J Immunopathol Pharmacol. 2021 Jan-Dec; 35:20587384211048026.
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Response to: 'Successful treatment of plasma exchange for refractory systemic juvenile idiopathic arthritis complicated with macrophage activation syndrome and severe lung disease' by Sato et al. Ann Rheum Dis. 2022 04; 81(4):e62.
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Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. J Clin Invest. 2020 04 01; 130(4):1669-1682.
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Fire behind the fury: IL-18 and MAS. Blood. 2018 03 29; 131(13):1393-1394.
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Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome. J Pediatr. 2017 10; 189:72-78.e3.