Immunoglobulin Light-chain Amyloidosis
"Immunoglobulin Light-chain Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
| Descriptor ID |
D000075363
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| MeSH Number(s) |
C04.557.595.250 C18.452.845.500.550 C20.683.515.507 C20.683.780.565
|
| Concept/Terms |
Immunoglobulin Light-chain Amyloidosis- Immunoglobulin Light-chain Amyloidosis
- Immunoglobulin Light chain Amyloidosis
- Immunoglobulin Light-chain Amyloidoses
- Amyloidosis, Primary
- AL Amyloidosis
- AL Amyloidoses
- Primary Systemic Amyloidosis
- Amyloidoses, Primary Systemic
- Amyloidosis, Primary Systemic
- Primary Systemic Amyloidoses
- Systemic Amyloidoses, Primary
- Systemic Amyloidosis, Primary
- Amyloidosis, Immunoglobulin Light-chain
- Amyloidosis, Immunoglobulin Light chain
- Primary Amyloidosis
- Amyloidoses, Primary
- Primary Amyloidoses
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light-chain Amyloidosis".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light-chain Amyloidosis".
This graph shows the total number of publications written about "Immunoglobulin Light-chain Amyloidosis" by people in this website by year, and whether "Immunoglobulin Light-chain Amyloidosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Light-chain Amyloidosis" by people in Profiles.
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Outcomes of t(11;14) light chain (AL) amyloidosis after autologous stem cell transplantation: benchmark for new therapies. Blood Cancer J. 2023 11 15; 13(1):170.
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Primary gastric amyloidosis associated with linitis plastica and delayed progression to systemic amyloidosis and multiple myeloma. BMJ Case Rep. 2023 May 29; 16(5).
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Report of consensus panel 1 from the 11th International Workshop on Waldenstrom's Macroglobulinemia on management of symptomatic, treatment-na?ve patients. Semin Hematol. 2023 03; 60(2):73-79.
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Amyloidosis of the Heart and Kidney. Methodist Debakey Cardiovasc J. 2022; 18(4):27-33.
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A second autologous hematopoietic cell transplantation is a safe and effective salvage therapy in select relapsed or refractory AL amyloidosis patients. Bone Marrow Transplant. 2022 02; 57(2):295-298.
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Evaluating the incidence of engraftment syndrome with different melphalan formulations in adult multiple myeloma and immunoglobulin light chain amyloidosis patients undergoing autologous hematopoietic cell transplantation. J Oncol Pharm Pract. 2022 Mar; 28(2):274-281.
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A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis. Kidney Int. 2021 03; 99(3):707-715.
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Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713.
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Time to Redefine Risk-Stratification and Response Criteria in Immunoglobulin Light Chain Amyloidosis? Clin Lymphoma Myeloma Leuk. 2020 10; 20(10):e769-e776.
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Incidence and characteristics of engraftment syndrome after autologous hematopoietic cell transplantation in light chain amyloidosis. Amyloid. 2019 Dec; 26(4):210-215.