Immunoglobulin Light-chain Amyloidosis
"Immunoglobulin Light-chain Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
| Descriptor ID |
D000075363
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| MeSH Number(s) |
C04.557.595.250 C18.452.845.500.550 C20.683.515.507 C20.683.780.565
|
| Concept/Terms |
Immunoglobulin Light-chain Amyloidosis- Immunoglobulin Light-chain Amyloidosis
- Immunoglobulin Light chain Amyloidosis
- Immunoglobulin Light-chain Amyloidoses
- Amyloidosis, Primary
- AL Amyloidosis
- AL Amyloidoses
- Primary Systemic Amyloidosis
- Amyloidoses, Primary Systemic
- Amyloidosis, Primary Systemic
- Primary Systemic Amyloidoses
- Systemic Amyloidoses, Primary
- Systemic Amyloidosis, Primary
- Amyloidosis, Immunoglobulin Light-chain
- Amyloidosis, Immunoglobulin Light chain
- Primary Amyloidosis
- Amyloidoses, Primary
- Primary Amyloidoses
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light-chain Amyloidosis".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light-chain Amyloidosis".
This graph shows the total number of publications written about "Immunoglobulin Light-chain Amyloidosis" by people in this website by year, and whether "Immunoglobulin Light-chain Amyloidosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Light-chain Amyloidosis" by people in Profiles.
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Multimodal Artificial Intelligence for Cardiac Amyloidosis Diagnosis: Integrating Echocardiography With Clinical and Laboratory Data for Improved Detection. Circ Cardiovasc Imaging. 2026 Jun; 19(6):e019610.
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Amyloidosis of the Heart and Kidney. Methodist Debakey Cardiovasc J. 2022; 18(4):27-33.
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Evaluating the incidence of engraftment syndrome with different melphalan formulations in adult multiple myeloma and immunoglobulin light chain amyloidosis patients undergoing autologous hematopoietic cell transplantation. J Oncol Pharm Pract. 2022 Mar; 28(2):274-281.
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A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis. Kidney Int. 2021 03; 99(3):707-715.
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Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713.
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Localized Lymph Node Light Chain Amyloidosis. Intern Med. 2020 Oct 01; 59(19):2415-2418.
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Incidence and characteristics of engraftment syndrome after autologous hematopoietic cell transplantation in light chain amyloidosis. Amyloid. 2019 Dec; 26(4):210-215.
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Orbital AL amyloid. Orbit. 2020 Feb; 39(1):68-70.
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Use of propylene glycol-free melphalan conditioning in light-chain amyloidosis patients undergoing autologous hematopoietic cell transplantation is well tolerated and effective. Bone Marrow Transplant. 2018 09; 53(9):1210-1213.
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Case report: isolated cardiac amyloidosis: an enigma unravelled. Methodist Debakey Cardiovasc J. 2015 Jan-Mar; 11(1):53-8.