"Leukemia, Hairy Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
| Descriptor ID |
D007943
|
| MeSH Number(s) |
C04.557.337.415 C15.604.515.553 C20.683.515.517
|
| Concept/Terms |
Leukemia, Hairy Cell- Leukemia, Hairy Cell
- Leukemic Reticuloendotheliosis
- Leukemic Reticuloendothelioses
- Reticuloendothelioses, Leukemic
- Reticuloendotheliosis, Leukemic
- Hairy Cell Leukemia
- Hairy Cell Leukemias
- Leukemias, Hairy Cell
|
Below are MeSH descriptors whose meaning is more general than "Leukemia, Hairy Cell".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Hairy Cell".
This graph shows the total number of publications written about "Leukemia, Hairy Cell" by people in this website by year, and whether "Leukemia, Hairy Cell" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia, Hairy Cell" by people in Profiles.
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Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Mol Cell. 2015 Aug 06; 59(3):345-358.
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Lymphomatous variant of hairy cell leukaemia: a distinctive presentation mimicking low-grade B-cell lymphoma. Histopathology. 2015 Nov; 67(5):740-5.
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Utility of quantitative flow cytometry immunophenotypic analysis of CD5 expression in small B-cell neoplasms. Arch Pathol Lab Med. 2014 Jul; 138(7):903-9.
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Update on the biology and treatment options for hairy cell leukemia. Curr Treat Options Oncol. 2014 Jun; 15(2):187-209.
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The bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) blocks hairy cell leukaemia survival, proliferation and B cell receptor signalling: a new therapeutic approach. Br J Haematol. 2014 Jul; 166(2):177-88.
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Treatment of hairy cell leukemia during pregnancy: are purine analogues and rituximab viable therapeutic options. Clin Lymphoma Myeloma Leuk. 2013 Feb; 13(1):86-9.
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Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay. Am J Clin Pathol. 2012 Jul; 138(1):153-6.
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The microenvironment in hairy cell leukemia: pathways and potential therapeutic targets. Leuk Lymphoma. 2011 Jun; 52 Suppl 2:94-8.
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Importance of minimal residual disease in hairy cell leukemia: monoclonal antibodies as a therapeutic strategy. Leuk Lymphoma. 2009 Oct; 50 Suppl 1:27-31.
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Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years. Cancer. 2008 Oct 01; 113(7 Suppl):1933-52.