"Neurofibroma, Plexiform" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestation of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131(5):678-82)
| Descriptor ID |
D018318
|
| MeSH Number(s) |
C04.557.580.600.580.585 C10.551.775.500.750.500 C10.668.829.725.500.600.500
|
| Concept/Terms |
Neurofibroma, Plexiform- Neurofibroma, Plexiform
- Neurofibromas, Plexiform
- Plexiform Neurofibroma
- Plexiform Neurofibromas
- Tumor Royale
- Pachydermatocele
- Pachydermatoceles
- Elephantiasis Neuromatosis
- Elephantiasis Neuromatoses
- Neuromas, Plexiform
- Neuroma, Plexiform
- Plexiform Neuroma
- Plexiform Neuromas
|
Below are MeSH descriptors whose meaning is more general than "Neurofibroma, Plexiform".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma, Plexiform".
This graph shows the total number of publications written about "Neurofibroma, Plexiform" by people in this website by year, and whether "Neurofibroma, Plexiform" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurofibroma, Plexiform" by people in Profiles.
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Clinical impact of selumetinib on pediatric elephantiasis neuromatosa. Pediatr Dermatol. 2022 Sep; 39(5):764-766.
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Image segmentation of plexiform neurofibromas from a deep neural network using multiple b-value diffusion data. Sci Rep. 2020 10 20; 10(1):17857.
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A molecular basis for neurofibroma-associated skeletal manifestations in NF1. Genet Med. 2020 11; 22(11):1786-1793.
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Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. Genet Med. 2019 04; 21(4):867-876.
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Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas. Pediatr Blood Cancer. 2014 Sep; 61(9):1598-602.
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Recurrent plexiform neurofibromatosis of the foot with extensive bone destruction. J Pediatr Orthop B. 2009 Jul; 18(4):176-8.
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Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas. J Clin Oncol. 2006 Jan 20; 24(3):507-16.