"Neurofibrosarcoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant tumor that arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei, hypocellular areas, and areas featuring organized whorls of fibroblastic proliferation. The most common primary sites are the extremities, retroperitoneum, and trunk. These tumors tend to present in childhood, often in association with NEUROFIBROMATOSIS 1. (From DeVita et al., Cancer: Principles & Practice of Oncology, 5th ed, p1662; Mayo Clin Proc 1990 Feb;65(2):164-72)
| Descriptor ID |
D018319
|
| MeSH Number(s) |
C04.557.450.565.590.350.590 C04.557.450.795.350.590 C04.557.580.600.580.795 C10.551.775.500.750.750 C10.668.829.725.500.600.600
|
| Concept/Terms |
Neurofibrosarcoma- Neurofibrosarcoma
- Neurofibrosarcomas
- Sarcoma, Neurogenic
- Neurogenic Sarcoma
- Neurogenic Sarcomas
- Sarcomas, Neurogenic
|
Below are MeSH descriptors whose meaning is more general than "Neurofibrosarcoma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibrosarcoma".
This graph shows the total number of publications written about "Neurofibrosarcoma" by people in this website by year, and whether "Neurofibrosarcoma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Neurofibrosarcoma" by people in Profiles.
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Loss of dimethylated H3K27 (H3K27me2) expression is not a specific marker of malignant peripheral nerve sheath tumor (MPNST): An immunohistochemical study of 137 cases, with emphasis on MPNST and melanocytic tumors. Ann Diagn Pathol. 2022 Aug; 59:151967.
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Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor. Lab Invest. 2022 06; 102(6):658-666.
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Not So Benign Bell's Palsy: Malignant Peripheral Nerve Sheath Tumor of the Facial Nerve Involving the Temporal Bone. J Gen Intern Med. 2021 04; 36(4):1102-1105.
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Radiation-associated sarcomas other than malignant peripheral nerve sheath tumours demonstrate loss of histone H3K27 trimethylation?. Histopathology. 2021 Jan; 78(2):321-326.
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ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study. Cancer. 2020 12 15; 126(24):5303-5310.
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BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor. Mod Pathol. 2019 03; 32(3):338-345.
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Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis: Impact of Family History. J Pediatr Hematol Oncol. 2018 08; 40(6):e359-e363.
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Malignant Peripheral Nerve Sheath Tumors: A Single Institution's Experience Using Combined Surgery and Radiation Therapy. Am J Clin Oncol. 2018 05; 41(5):465-470.
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Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers. J Neurosurg. 2018 09; 129(3):805-814.
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Hemisacrectomy with preservation of the contralateral sacral nerve roots and sacroiliac joint for pelvic neurofibrosarcoma in a 7-year-old child: case report with 2-year follow-up. J Neurosurg Pediatr. 2017 Jan; 19(1):102-107.