"Neurofibroma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Descriptor ID |
D009455
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| MeSH Number(s) |
C04.557.580.600.580 C10.551.775.500.750 C10.668.829.725.500.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Neurofibroma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma".
This graph shows the total number of publications written about "Neurofibroma" by people in this website by year, and whether "Neurofibroma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 3 | 0 | 3 |
| 1999 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neurofibroma" by people in Profiles.
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TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3. Hum Pathol. 2024 09; 151:105632.
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A molecular basis for neurofibroma-associated skeletal manifestations in NF1. Genet Med. 2020 11; 22(11):1786-1793.
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Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers. J Neurosurg. 2018 09; 129(3):805-814.
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The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours. Histopathology. 2017 May; 70(6):946-953.
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Myxoid Dermatofibrosarcoma Protuberans of the Vulva: Case Report of a Rare Variant in an Unusual Location, With Unusual Morphologic and Immunohistochemical Features. Am J Dermatopathol. 2016 Mar; 38(3):226-30.
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Neurofibromas of the Phrenic Nerve: A Case Report and Review of the Literature. World Neurosurg. 2016 Apr; 88:237-242.
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Myxoid neurofibroma treated with Mohs micrographic surgery. Dermatol Surg. 2015 Jan; 41(1):166-8.
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Hybrid neurofibroma-schwannoma of the orbit. Orbit. 2008; 27(3):223-5.
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Metastatic acinic cell carcinoma in a neurofibroma mistaken for carcinosarcoma. Head Neck. 2005 Jan; 27(1):76-80.
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Case studies for illustration and discussion: peripheral nerve tumors. Neurosurg Clin N Am. 2004 Apr; 15(2):241-9, viii.