"Bone Remodeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
| Descriptor ID |
D016723
|
| MeSH Number(s) |
G11.427.213 G16.762.150
|
| Concept/Terms |
Bone Remodeling- Bone Remodeling
- Remodeling, Bone
- Bone Turnover
- Bone Turnovers
- Turnover, Bone
- Turnovers, Bone
|
Below are MeSH descriptors whose meaning is more general than "Bone Remodeling".
Below are MeSH descriptors whose meaning is more specific than "Bone Remodeling".
This graph shows the total number of publications written about "Bone Remodeling" by people in this website by year, and whether "Bone Remodeling" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 4 | 1 | 5 |
| 2011 | 1 | 3 | 4 |
| 2013 | 5 | 1 | 6 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 3 | 2 | 5 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 3 | 0 | 3 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bone Remodeling" by people in Profiles.
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Update on the role of bone turnover markers in the diagnosis and management of osteoporosis: a consensus paper from The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), International Osteoporosis Foundation (IOF), and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). Osteoporos Int. 2025 Apr; 36(4):579-608.
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Clinically relevant doses of tiludronate do not affect bone remodelling in pasture-exercised horses. Equine Vet J. 2025 Mar; 57(2):513-521.
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Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells. Cancer Discov. 2023 02 06; 13(2):474-495.
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Hemoglobin A1c Threshold for Reduction in Bone Turnover in Men With Type 2 Diabetes Mellitus. Front Endocrinol (Lausanne). 2021; 12:788107.
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Testosterone Therapy Effects on Bone Mass and Turnover in Hypogonadal Men with Type 2 Diabetes. J Clin Endocrinol Metab. 2021 07 13; 106(8):e3058-e3068.
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In Men With Obesity, T2DM Is Associated With Poor Trabecular Microarchitecture and Bone Strength and Low Bone Turnover. J Clin Endocrinol Metab. 2021 04 23; 106(5):1362-1376.
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Exploiting bone niches: progression of disseminated tumor cells to metastasis. J Clin Invest. 2021 03 15; 131(6).
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Heme Oxygenase-1 Is a Pivotal Modulator of Bone Turnover and Remodeling: Molecular Implications for Prostate Cancer Bone Metastasis. Antioxid Redox Signal. 2020 06 10; 32(17):1243-1258.
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CApecitabine plus Radium-223 (Xofigo?) in breast cancer patients with BONe metastases (CARBON): study protocol for a phase IB/IIA randomised controlled trial. Trials. 2020 Jan 15; 21(1):89.
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Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020 01 07; 11(1):87.