"Succinate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
| Descriptor ID |
D013385
|
| MeSH Number(s) |
D05.500.562.750.249.500 D08.811.600.250.500.750.500 D08.811.600.250.875.249.500 D08.811.682.660.385.500 D08.811.682.830.249.500 D12.776.157.427.374.375.909.500 D12.776.331.199.750.500 D12.776.543.277.500.750.500 D12.776.543.277.875.249.500 D12.776.556.579.374.375.141.500
|
| Concept/Terms |
Succinate Dehydrogenase- Succinate Dehydrogenase
- Dehydrogenase, Succinate
- Succinic Dehydrogenase
- Dehydrogenase, Succinic
- Succinic Oxidase
- Oxidase, Succinic
- Fumarate Reductase
- Reductase, Fumarate
|
Below are MeSH descriptors whose meaning is more general than "Succinate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate Dehydrogenase".
This graph shows the total number of publications written about "Succinate Dehydrogenase" by people in this website by year, and whether "Succinate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Succinate Dehydrogenase" by people in Profiles.
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Mitochondrial complex II orchestrates divergent effects in CD4+ and CD8+ T cells. J Clin Invest. 2025 Dec 15; 135(24).
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Update on Tumor Surveillance for Children with Hereditary Pheochromocytoma/Paraganglioma Syndromes. Clin Cancer Res. 2025 Aug 14; 31(16):3368-3376.
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Ancestry-specific predisposing germline variants in cancer. Genome Med. 2020 05 29; 12(1):51.
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Tumor-specific prognosis of mutation-positive patients with head and neck paragangliomas. J Vasc Surg. 2020 05; 71(5):1602-1612.e2.
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The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons. Immunity. 2019 01 15; 50(1):64-76.e4.
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Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism. Oncol Rep. 2017 Apr; 37(4):1971-1979.
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Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis. J Biol Chem. 2011 Sep 16; 286(37):32843-53.
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Novel germline SDHD mutation: diagnosis and implications to the patient. Fam Cancer. 2011 Jun; 10(2):365-71.
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Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry. 2010 Jan 19; 49(2):304-11.
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Influence of Ramadan-type fasting on enzymes of carbohydrate metabolism and brush border membrane in small intestine and liver of rat used as a model. Br J Nutr. 2006 Dec; 96(6):1087-94.