"Succinate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
| Descriptor ID |
D013385
|
| MeSH Number(s) |
D05.500.562.750.249.500 D08.811.600.250.500.750.500 D08.811.600.250.875.249.500 D08.811.682.660.385.500 D08.811.682.830.249.500 D12.776.157.427.374.375.909.500 D12.776.331.199.750.500 D12.776.543.277.500.750.500 D12.776.543.277.875.249.500 D12.776.556.579.374.375.141.500
|
| Concept/Terms |
Succinate Dehydrogenase- Succinate Dehydrogenase
- Dehydrogenase, Succinate
- Succinic Dehydrogenase
- Dehydrogenase, Succinic
- Succinic Oxidase
- Oxidase, Succinic
- Fumarate Reductase
- Reductase, Fumarate
|
Below are MeSH descriptors whose meaning is more general than "Succinate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate Dehydrogenase".
This graph shows the total number of publications written about "Succinate Dehydrogenase" by people in this website by year, and whether "Succinate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Succinate Dehydrogenase" by people in Profiles.
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SDHB-Associated Pheochromocytomas: What is Their Clinical Behavior? Ann Surg Oncol. 2024 Dec; 31(13):9007-9013.
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Management of phaeochromocytoma and paraganglioma in patients with germline SDHB pathogenic variants: an international expert Consensus statement. Nat Rev Endocrinol. 2024 Mar; 20(3):168-184.
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Succinate Dehydrogenase Mutations as Familial Pheochromocytoma Syndromes. Surg Oncol Clin N Am. 2023 04; 32(2):289-301.
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Clinical consensus guideline on the management of phaeochromocytoma and paraganglioma in patients harbouring germline SDHD pathogenic variants. Lancet Diabetes Endocrinol. 2023 05; 11(5):345-361.
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SDHx mutations and temozolomide in malignant pheochromocytoma and paraganglioma. Endocr Relat Cancer. 2022 09 01; 29(9):533-544.
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International consensus on initial screening and follow-up of asymptomatic SDHx mutation carriers. Nat Rev Endocrinol. 2021 07; 17(7):435-444.
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Ancestry-specific predisposing germline variants in cancer. Genome Med. 2020 05 29; 12(1):51.
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Cardiac paragangliomas: A case series with clinicopathologic features and succinate dehydrogenase B immunostaining. Ann Diagn Pathol. 2020 Apr; 45:151477.
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Tumor-specific prognosis of mutation-positive patients with head and neck paragangliomas. J Vasc Surg. 2020 05; 71(5):1602-1612.e2.
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Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma. Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4187-4195.