Transcriptional Elongation Factors
"Transcriptional Elongation Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcription factors whose primary function is to regulate the rate in which RNA is transcribed.
| Descriptor ID |
D035602
|
| MeSH Number(s) |
D12.776.930.955
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Transcriptional Elongation Factors".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Elongation Factors".
This graph shows the total number of publications written about "Transcriptional Elongation Factors" by people in this website by year, and whether "Transcriptional Elongation Factors" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transcriptional Elongation Factors" by people in Profiles.
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Genomic analyses in Cornelia de Lange Syndrome and related diagnoses: Novel candidate genes, genotype-phenotype correlations and common mechanisms. Am J Med Genet A. 2023 08; 191(8):2113-2131.
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The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder. Biochem Soc Trans. 2023 02 27; 51(1):125-135.
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Tandem Affinity Purification and Mass-Spectrometric Analysis of FACT and Associated Proteins. Methods Mol Biol. 2023; 2701:209-227.
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A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth. J Hematol Oncol. 2022 04 08; 15(1):41.
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A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science. 2021 Nov 26; 374(6571):1113-1121.
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Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth. Theranostics. 2021; 11(17):8172-8184.
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Variants in the degron of AFF3 are associated with intellectual disability, mesomelic dysplasia, horseshoe kidney, and epileptic encephalopathy. Am J Hum Genet. 2021 05 06; 108(5):857-873.
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Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription. Mol Cell Biol. 2021 03 24; 41(4).
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Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol. 2020 04 07; 3(1):165.
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Germline Elongator mutations in Sonic Hedgehog medulloblastoma. Nature. 2020 04; 580(7803):396-401.