Interferon Regulatory Factors
"Interferon Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
| Descriptor ID |
D050835
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| MeSH Number(s) |
D12.644.360.024.302 D12.776.157.057.050 D12.776.260.504 D12.776.476.024.385 D12.776.930.332
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factors".
This graph shows the total number of publications written about "Interferon Regulatory Factors" by people in this website by year, and whether "Interferon Regulatory Factors" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factors" by people in Profiles.
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Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis. Nat Commun. 2023 02 24; 14(1):1069.
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Transcriptional Plasticity Drives Leukemia Immune Escape. Blood Cancer Discov. 2022 09 06; 3(5):394-409.
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MUM1/IRF4 is Highly Expressed in Dermatopathic Lymphadenopathy: Potential Utility in Diagnosis and Differential Diagnosis. Am J Surg Pathol. 2022 11 01; 46(11):1514-1523.
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IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. Blood Adv. 2022 04 12; 6(7):2254-2266.
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A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia. Genes Dev. 2022 03 01; 36(5-6):368-389.
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Predicting unrecognized enhancer-mediated genome topology by an ensemble machine learning model. Genome Res. 2020 12; 30(12):1835-1845.
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Consensus transcriptional regulatory networks of coronavirus-infected human cells. Sci Data. 2020 09 22; 7(1):314.
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PBX-WNT-P63-IRF6 pathway in nonsyndromic cleft lip and palate. Birth Defects Res. 2020 02 01; 112(3):234-244.
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Diffuse large B-cell lymphoma variants: an update. Pathology. 2020 Jan; 52(1):53-67.
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The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737.