Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
| Descriptor ID |
D048868
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| MeSH Number(s) |
D12.644.360.024 D12.776.157.057 D12.776.476.024
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 3 | 5 |
| 2001 | 5 | 2 | 7 |
| 2002 | 4 | 6 | 10 |
| 2003 | 3 | 7 | 10 |
| 2004 | 4 | 11 | 15 |
| 2005 | 2 | 9 | 11 |
| 2006 | 1 | 7 | 8 |
| 2007 | 7 | 8 | 15 |
| 2008 | 1 | 7 | 8 |
| 2009 | 8 | 4 | 12 |
| 2010 | 10 | 14 | 24 |
| 2011 | 8 | 11 | 19 |
| 2012 | 4 | 10 | 14 |
| 2013 | 10 | 9 | 19 |
| 2014 | 14 | 9 | 23 |
| 2015 | 17 | 13 | 30 |
| 2016 | 13 | 8 | 21 |
| 2017 | 8 | 14 | 22 |
| 2018 | 5 | 8 | 13 |
| 2019 | 7 | 7 | 14 |
| 2020 | 9 | 4 | 13 |
| 2021 | 4 | 5 | 9 |
| 2022 | 1 | 9 | 10 |
| 2023 | 1 | 5 | 6 |
| 2024 | 4 | 5 | 9 |
| 2025 | 2 | 2 | 4 |
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Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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?-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
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Maternal loss of mouse Nlrp2 alters the transcriptome and DNA methylome in GV oocytes and impairs zygotic genome activation in embryos. Clin Epigenetics. 2025 Jun 03; 17(1):92.
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Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition. Nat Commun. 2025 Mar 18; 16(1):2641.
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2420961122.
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Anaplastic meningioma in a 6-year-old with somatic YAP1::MAML2 fusion and multiple endocrine neoplasia type 4 (MEN4) syndrome. Cancer Genet. 2025 Apr; 292-293:106-110.
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Genetic Variants in Severe Hypertriglyceridemia Among Taiwanese Participants - Insights From Genome-Wide Association and Whole-Exome Sequencing Analyses. Circ J. 2025 Feb 25; 89(3):331-339.
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HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Lett. 2025 Feb 01; 610:217354.
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Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation. Commun Biol. 2024 Nov 21; 7(1):1554.
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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The RNA receptor RIG-I binding synthetic oligodeoxynucleotide promotes pneumonia survival. JCI Insight. 2024 Nov 08; 9(21).