Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
| Descriptor ID |
D048868
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| MeSH Number(s) |
D12.644.360.024 D12.776.157.057 D12.776.476.024
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1995 | 1 | 0 | 1 |
| 1996 | 3 | 1 | 4 |
| 1997 | 5 | 5 | 10 |
| 1998 | 8 | 6 | 14 |
| 1999 | 8 | 5 | 13 |
| 2000 | 8 | 8 | 16 |
| 2001 | 11 | 10 | 21 |
| 2002 | 10 | 20 | 30 |
| 2003 | 12 | 24 | 36 |
| 2004 | 12 | 28 | 40 |
| 2005 | 5 | 20 | 25 |
| 2006 | 14 | 25 | 39 |
| 2007 | 13 | 20 | 33 |
| 2008 | 14 | 26 | 40 |
| 2009 | 22 | 21 | 43 |
| 2010 | 18 | 29 | 47 |
| 2011 | 23 | 29 | 52 |
| 2012 | 14 | 25 | 39 |
| 2013 | 23 | 19 | 42 |
| 2014 | 24 | 15 | 39 |
| 2015 | 32 | 23 | 55 |
| 2016 | 19 | 15 | 34 |
| 2017 | 17 | 18 | 35 |
| 2018 | 15 | 12 | 27 |
| 2019 | 15 | 13 | 28 |
| 2020 | 14 | 6 | 20 |
| 2021 | 9 | 12 | 21 |
| 2022 | 3 | 11 | 14 |
| 2023 | 1 | 9 | 10 |
| 2024 | 8 | 10 | 18 |
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Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Lett. 2025 Feb 01; 610:217354.
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Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation. Commun Biol. 2024 Nov 21; 7(1):1554.
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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The RNA receptor RIG-I binding synthetic oligodeoxynucleotide promotes pneumonia survival. JCI Insight. 2024 Nov 08; 9(21).
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YAP1 Status Defines Two Intrinsic Subtypes of LCNEC with Distinct Molecular Features and Therapeutic Vulnerabilities. Clin Cancer Res. 2024 Oct 15; 30(20):4743-4754.
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Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.
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Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk. Cancer Discov. 2024 Oct 04; 14(10):1838-1859.
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Optimal Humanized Scg3-Neutralizing Antibodies for Anti-Angiogenic Therapy of Diabetic Retinopathy. Int J Mol Sci. 2024 Sep 01; 25(17).
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Exploring the PDZ, DUF, and LIM Domains of Pdlim5 in Dendrite Branching. Int J Mol Sci. 2024 Jul 30; 25(15).
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A Potential Role for MAGI-1 in the Bi-Directional Relationship Between Major Depressive Disorder and Cardiovascular Disease. Curr Atheroscler Rep. 2024 Sep; 26(9):463-483.