ZAP-70 Protein-Tyrosine Kinase
"ZAP-70 Protein-Tyrosine Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR function.
| Descriptor ID |
D051746
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.900 D12.776.476.950
|
| Concept/Terms |
ZAP-70 Protein-Tyrosine Kinase- ZAP-70 Protein-Tyrosine Kinase
- Protein-Tyrosine Kinase, ZAP-70
- ZAP 70 Protein Tyrosine Kinase
- ZAP-70 Kinase
- Kinase, ZAP-70
- ZAP 70 Kinase
- zeta-Chain Associated Protein Kinase (ZAP-70)
- 70 kDa Zeta-Associated Protein
- 70 kDa Zeta Associated Protein
- ZAP-70 Protein
- ZAP 70 Protein
- Syk-Related Tyrosine Kinase
- Syk Related Tyrosine Kinase
- Tyrosine Kinase, Syk-Related
|
Below are MeSH descriptors whose meaning is more general than "ZAP-70 Protein-Tyrosine Kinase".
Below are MeSH descriptors whose meaning is more specific than "ZAP-70 Protein-Tyrosine Kinase".
This graph shows the total number of publications written about "ZAP-70 Protein-Tyrosine Kinase" by people in this website by year, and whether "ZAP-70 Protein-Tyrosine Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "ZAP-70 Protein-Tyrosine Kinase" by people in Profiles.
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Combined immunodeficiency caused by pathogenic variants in the ZAP70 C-terminal SH2 domain. Front Immunol. 2023; 14:1155883.
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B-cell Receptor Signaling Regulates Metabolism in Chronic Lymphocytic Leukemia. Mol Cancer Res. 2017 12; 15(12):1692-1703.
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CD49d shows superior performance characteristics for flow cytometric prognostic testing in chronic lymphocytic leukemia/small lymphocytic lymphoma. Cytometry B Clin Cytom. 2018 01; 94(1):129-135.
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Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia. Cancer Res. 2014 May 01; 74(9):2520-32.
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Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. J Allergy Clin Immunol. 2014 Apr; 133(4):1109-15.
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Identification of a novel mutation in ZAP70 and prenatal diagnosis in a Turkish family with severe combined immunodeficiency disorder. Gene. 2013 Jan 10; 512(2):189-93.
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Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia. J Clin Oncol. 2011 Nov 01; 29(31):4088-95.
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Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features. Am J Clin Pathol. 2011 May; 135(5):686-96.
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CCL3 (MIP-1a) plasma levels and the risk for disease progression in chronic lymphocytic leukemia. Blood. 2011 Feb 03; 117(5):1662-9.
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High serum thymidine kinase 1 level predicts poorer survival in patients with chronic lymphocytic leukemia. Am J Clin Pathol. 2010 Sep; 134(3):472-7.