"Cyclins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
| Descriptor ID |
D016213
|
| MeSH Number(s) |
D12.644.360.262 D12.776.167.218 D12.776.476.262
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclins".
Below are MeSH descriptors whose meaning is more specific than "Cyclins".
This graph shows the total number of publications written about "Cyclins" by people in this website by year, and whether "Cyclins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 2 | 5 |
| 1997 | 2 | 1 | 3 |
| 1998 | 1 | 1 | 2 |
| 1999 | 6 | 3 | 9 |
| 2000 | 0 | 4 | 4 |
| 2001 | 1 | 1 | 2 |
| 2002 | 5 | 2 | 7 |
| 2003 | 4 | 6 | 10 |
| 2004 | 5 | 7 | 12 |
| 2005 | 1 | 1 | 2 |
| 2006 | 3 | 0 | 3 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclins" by people in Profiles.
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Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt. Mol Cell Biol. 2020 03 30; 40(8).
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Subversion of Cell Cycle Regulatory Mechanisms by HIV. Cell Host Microbe. 2015 Jun 10; 17(6):736-40.
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P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 01; 307(11):G1073-87.
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New structural insights into phosphorylation-free mechanism for full cyclin-dependent kinase (CDK)-cyclin activity and substrate recognition. J Biol Chem. 2013 Oct 18; 288(42):30682-30692.
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Too many breaks (brakes): pancreatic ?-cell senescence leads to diabetes. Cell Cycle. 2011 Aug 01; 10(15):2471-84.
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Expression of the Argonaute protein PiwiL2 and piRNAs in adult mouse mesenchymal stem cells. Biochem Biophys Res Commun. 2010 Jun 11; 396(4):915-20.
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GSK3beta-cyclin D3-CUGBP1-eIF2 pathway in aging and in myotonic dystrophy. Cell Cycle. 2009 Aug; 8(15):2356-9.
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Nuclear cyclin B1 is overexpressed in low-malignant-potential ovarian tumors but not in epithelial ovarian cancer. Am J Obstet Gynecol. 2009 Oct; 201(4):367.e1-6.
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Dysregulation of positive transcription elongation factor B and myocardial hypertrophy. Circ Res. 2009 Jun 19; 104(12):1327-9.
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The age-associated decline of glycogen synthase kinase 3beta plays a critical role in the inhibition of liver regeneration. Mol Cell Biol. 2009 Jul; 29(14):3867-80.